Females' Knowledge and Use of Isotretinoin (Roaccutane) in the Western Region of Saudi Arabia

Bakheet, Kholoud Mohammed A; Alghanemi, Rand G; Alsiyoufi, Alya M; Abduljabbar, Mohammed H; Hariri, Jehad

doi:10.7759/cureus.12148

Cited by 11 publications

(24 citation statements)

References 16 publications

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“…Dryness of the skin, eyes, and lips were the top three side effects identified by the respondents, followed by nose dryness and bleeding. These results are similar to those reported in several cross-sectional studies [24,25,27], where the dryness of the eyes, lips, and skin were the most common side effects. On the other hand, the least experienced side effect was depression; this result is consistent with what was observed in previous studies [13,28].…”

Section: Resultssupporting

confidence: 91%

“…Another explanation would be the source of information regarding Isotretinoin, with 50% of the respondents relying on relatives/friends or social media as a source of information. Nonetheless, our results are also consistent with those reported in another crosssectional study in Western Saudi Arabia which showed even lower knowledge regarding the teratogenic effect of Isotretinoin [25]. The similarity in knowledge can be explained by the similarities in the demographic characteristics (marital status and age), particularly the lower age of the included participants.…”

Section: Resultssupporting

confidence: 91%

“…It has also been suggested that a contraceptive information sheet can significantly improve the knowledge of the patients regarding contraception and may prevent isotretinoininduced congenital disabilities [33]. The knowledge regarding the side effects of Isotretinoin was significantly higher in users than non-users previously reported in the literature [12,25]. With so many patients taking medicines for a variety of ailments, it's critical for doctors to know what prescriptions their patients are taking, why they're taking them, and if they're suffering any adverse effects.…”

Section: Resultsmentioning

confidence: 99%

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The Prevalence of using Prescribed & Unprescribed “Roaccutane (Isotretinoin)” among Females Riyadh, Saudi Arabia: A Cross Sectional Study

Mahmoud

Almohaini

Assiri

et al. 2021

JPRI

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Aims: To determine the prevalence of using prescribed and unprescribed Isotretinoin and to assess knowledge of its adverse effects among females in Riyadh, SA. Study design: cross-sectional study. Place and Duration of Study: online questionnaire collected throughout two months by distributing the questionnaire via. social media platforms. Methodology: We included 385 female patients (age range 15-45 years) use Roaccutane (Isotretinoin) with or without prescribed. Statistical analysis was performed using Rv 3.6.3. Counts and percentages was used to summarize the distribution of categorical variables and data. Chi-square test was used to estimate the association between categorical variables. Hypothesis testing was performed at a 5% level of significance. Results: 568 respondents completed the questionnaire. Of these, 440 were from Riyadh. The majority of respondents were aged 15 – 20 (46.4%) and 21 – 25 (35.2%). Knowledge regarding some side effects of Roaccutane was significantly higher in respondents who reported using Roaccutane than those who did not. Knowledge of dry and cracked lips as a side effect was significantly higher in users (91.9%) than non-users (73.1%). Similarly, knowledge regarding dry eyes, depression, continuous thirst, nose dryness, bleeds, and effect of Roaccutane on liver biochemical profile, lipid profile, and bones was higher in users than non-users, regarding the teratogenic effect of Roaccutane was insignificantly different between groups. Conclusion: Females in Riyadh are aware of the side effects of isotretinoin, particularly dryness of the skin, eyes, and lips. Yet there is insufficient knowledge regarding its teratogenic effect. Based on the reported results, a few participants obtained Roaccutane without a prescription from the doctor, and some obtained their information from unreliable sources (i.e., friends/relatives). Our results suggest good practice towards the prescription of isotretinoin.

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Section: Resultssupporting

confidence: 91%

Section: Resultssupporting

confidence: 91%

Section: Resultsmentioning

confidence: 99%

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The Prevalence of using Prescribed & Unprescribed “Roaccutane (Isotretinoin)” among Females Riyadh, Saudi Arabia: A Cross Sectional Study

Mahmoud

Almohaini

Assiri

et al. 2021

JPRI

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“…Younis and Al- Harbi, 2019;Bakheet et al, 2020;Ibrahim et al, 2021;Al-Mekhlafi et al, 2021). As shown in this study, public awareness of topical retinoid contraindications was inadequate; this is linked to the importance of taking topical retinoids only after consulting a doctor or pharmacist to avoid teratogenicity and other side effects.Furthermore, educate the public about it.…”

mentioning

confidence: 87%

“…Some 84.6% of users were informed of the drug's side effects. However, this study included females only, and 82.7% of the population were from Jeddah (Bakheet et al, 2020). However, no study was done about the use of topical retinoids in Saudi population.…”

Section: Introductionmentioning

confidence: 99%

Prevalence, knowledge, attitude and practice of using topical retinoids among Saudi population, Saudi Arabia

Alsharif¹,

Alosaimi²,

Aldoobi³

et al. 2022

Medical Science

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Background: Vitamin A (all-trans-retinol) derivatives are collectively referred to as retinoids. It is FDA approved to treat acne. We aimed to assess the prevalence, knowledge, attitude, and practice of using topical retinoids among all the region's populations. Methods: A cross-sectional study was carried out in all Saudi Arabian regions from October 2021 to November 2021 through a verified electronic-based self-administered questionnaire. Results: The survey questionnaire was completed by a total of 1,139 people. In Saudi Arabia, the frequency of acne among males and females is approximately 73.2 percent. The subject's knowledge of topical retinoids contraindicates is spread out between 44.6 percent and 77.5 percent. Approximately half of the study participants took topical retinoids without a prescription. Conclusion: In this study, the most commonly reported effect after using topical retinoids was a reduction in acne formation. This indicates that topical retinoids have a very good effect in the treatment of acne. The other preferable outcomes to use retinoids include preventing wrinkles and facial lines, as well as enhancing skin brightness. The majority did not seek a medical prescription for topical retinoids and did not utilize them properly, which lowered their satisfaction with the benefits of topical retinoids.

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Awareness of isotretinoin use and safety in Saudi Arabia: A nationwide cross-sectional study

Alshehri,

Althobaiti,

Khawagi

et al. 2023

Saudi Pharmaceutical Journal

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Females' Knowledge and Use of Isotretinoin (Roaccutane) in the Western Region of Saudi Arabia

Cited by 11 publications

References 16 publications

The Prevalence of using Prescribed & Unprescribed “Roaccutane (Isotretinoin)” among Females Riyadh, Saudi Arabia: A Cross Sectional Study

The Prevalence of using Prescribed & Unprescribed “Roaccutane (Isotretinoin)” among Females Riyadh, Saudi Arabia: A Cross Sectional Study

Prevalence, knowledge, attitude and practice of using topical retinoids among Saudi population, Saudi Arabia

Awareness of isotretinoin use and safety in Saudi Arabia: A nationwide cross-sectional study

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