Fermented black barley ameliorates lung injury induced by cooking oil fumes via antioxidant activity and regulation of the intestinal microbiome in mice

XianBin, Ding; Yang, Li; Qi, Guijun; Zeng, Hui; Song, Chenwei; Wu, Jiayi; Liu, Song

doi:10.1016/j.ecoenv.2020.110473

Cited by 15 publications

(2 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of this study are compelling because they go against what has been previously reported in the literature [30,31,[36][37][38]. As mentioned above, fermentation should increase the flavonoid content of a plant because the process per se converts bound flavonoids into free form [27].…”

Section: Resultssupporting

confidence: 55%

Comparison of the contents of total polyphenol, total flavonoid, and flavonoid derivatives in unfermented and fermented barley sprouts

Uy,

Lee,

Byun

et al. 2023

JABC

View full text Add to dashboard Cite

Barley (Hordeum vulgare) belongs to the Poaceae family. This study compared the polyphenol and flavonoid levels of unfermented and fermented barley sprouts using spectrophotometric assays. The findings indicated that fermentation greatly boosted the flavonoid content but caused only a slight increase in the polyphenol content. However, this does not imply that fermentation has no effects whatsoever on the polyphenol content of barley sprouts. This was due to the fact that some flavonoids cannot be detected by the wavelength used to calculate the overall polyphenol concentration. Both samples were subjected to high-performance liquid chromatography analysis and detected the flavonoids lutonarin, saponarin, isoorientin, isovitexin, and tricin-all of which have bioactive properties-most notably known for their antioxidant activity. These results augment the ongoing phytochemical profiling research and can possibly valorize the already thriving barley industry.

show abstract

Section: Resultssupporting

confidence: 55%

Comparison of the contents of total polyphenol, total flavonoid, and flavonoid derivatives in unfermented and fermented barley sprouts

Uy,

Lee,

Byun

et al. 2023

JABC

View full text Add to dashboard Cite

show abstract

“…We also observed increases in potentially beneficial gut bacteria after inhalation exposure. The presence of certain bacteria known to function in maintaining host immunomodulatory balance such as Lactobacillus, Enterococcus faecalis, Streptococcus, and Bifidobacterium indicates a potential adaptive mechanism of the gut microbiome [ 88 – 90 ]. Overall, this indicates that inhalation co-exposure imbalances gut microbial composition toward a potential adaptive/homeostatic change.…”

Section: Discussionmentioning

confidence: 99%

Lung-gut axis of microbiome alterations following co-exposure to ultrafine carbon black and ozone

et al. 2023

View full text Add to dashboard Cite

Background Microbial dysbiosis is a potential mediator of air pollution-induced adverse outcomes. However, a systemic comparison of the lung and gut microbiome alterations and lung-gut axis following air pollution exposure is scant. In this study, we exposed male C57BL/6J mice to inhaled air, CB (10 mg/m3), O3 (2 ppm) or CB + O3 mixture for 3 h/day for either one day or four consecutive days and were euthanized 24 h post last exposure. The lung and gut microbiome were quantified by 16 s sequencing. Results Multiple CB + O3 exposures induced an increase in the lung inflammatory cells (neutrophils, eosinophils and B lymphocytes), reduced absolute bacterial load in the lungs and increased load in the gut. CB + O3 exposure was more potent as it decreased lung microbiome alpha diversity just after a single exposure. CB + O3 co-exposure uniquely increased Clostridiaceae and Prevotellaceae in the lungs. Serum short chain fatty acids (SCFA) (acetate and propionate) were increased significantly only after CB + O3 co-exposure. A significant increase in SCFA producing bacterial families (Ruminococcaceae, Lachnospiraceae, and Eubacterium) were also observed in the gut after multiple exposures. Co-exposure induced significant alterations in the gut derived metabolite receptors/mediator (Gcg, Glp-1r, Cck) mRNA expression. Oxidative stress related mRNA expression in lungs, and oxidant levels in the BALF, serum and gut significantly increased after CB + O3 exposures. Conclusion Our study confirms distinct gut and lung microbiome alterations after CB + O3 inhalation co-exposure and indicate a potential homeostatic shift in the gut microbiome to counter deleterious impacts of environmental exposures on metabolic system.

show abstract

A systematic review of the carcinogenicity of rats and mice by sex due to exposure to phenyl compounds

Rim

2024

Mol. Cell. Toxicol.

View full text Add to dashboard Cite

Fermented black barley ameliorates lung injury induced by cooking oil fumes via antioxidant activity and regulation of the intestinal microbiome in mice

Cited by 15 publications

References 41 publications

Comparison of the contents of total polyphenol, total flavonoid, and flavonoid derivatives in unfermented and fermented barley sprouts

Comparison of the contents of total polyphenol, total flavonoid, and flavonoid derivatives in unfermented and fermented barley sprouts

Lung-gut axis of microbiome alterations following co-exposure to ultrafine carbon black and ozone

A systematic review of the carcinogenicity of rats and mice by sex due to exposure to phenyl compounds

Contact Info

Product

Resources

About