Fermented soybean meal extract improves oxidative stress factors in the lung of inflammation/infection animal model

Miri, Saba; Hajihosseini, Reza; Saedi, Hamed; Vaseghi, Maryam; Rasooli, Azadeh

doi:10.1007/s13213-019-01534-y

Cited by 14 publications

(7 citation statements)

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“…Additionally, peptides produced by Lactobacillus spp.-mediated soy milk fermentation exhibited antioxidant activity by enhancing the abovementioned activity-related factors [140][141][142][143][144]. Peptides produced by fermentation based on Lactobacillus spp.-mediated soybean meal extract [145] and Chryseobacterium sp.-mediated SPI [146] exhibited significant antioxidant activity.…”

Section: Antioxidative Propertiesmentioning

confidence: 98%

Beneficial Effects of Soybean-Derived Bioactive Peptides

Kim

Yang²,

Kim

2021

IJMS

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Peptides present in foods are involved in nutritional functions by supplying amino acids; sensory functions related to taste or solubility, emulsification, etc.; and bioregulatory functions in various physiological activities. In particular, peptides have a wide range of physiological functions, including as anticancer agents and in lowering blood pressure and serum cholesterol levels, enhancing immunity, and promoting calcium absorption. Soy protein can be partially hydrolyzed enzymatically to physiologically active soy (or soybean) peptides (SPs), which not only exert physiological functions but also help amino acid absorption in the body and reduce bitterness by hydrolyzing hydrophobic amino acids from the C- or N-terminus of soy proteins. They also possess significant gel-forming, emulsifying, and foaming abilities. SPs are expected to be able to prevent and treat atherosclerosis by inhibiting the reabsorption of bile acids in the digestive system, thereby reducing blood cholesterol, low-density lipoprotein, and fat levels. In addition, soy contains blood pressure-lowering peptides that inhibit angiotensin-I converting enzyme activity and antithrombotic peptides that inhibit platelet aggregation, as well as anticancer, antioxidative, antimicrobial, immunoregulatory, opiate-like, hypocholesterolemic, and antihypertensive activities. In animal models, neuroprotective and cognitive capacity as well as cardiovascular activity have been reported. SPs also inhibit chronic kidney disease and tumor cell growth by regulating the expression of genes associated with apoptosis, inflammation, cell cycle arrest, invasion, and metastasis. Recently, various functions of soybeans, including their physiologically active functions, have been applied to health-oriented foods, functional foods, pharmaceuticals, and cosmetics. This review introduces some current results on the role of bioactive peptides found in soybeans related to health functions.

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Section: Antioxidative Propertiesmentioning

confidence: 98%

Beneficial Effects of Soybean-Derived Bioactive Peptides

Kim

Yang²,

Kim

2021

IJMS

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“…The nature of the process has a significant impact on the biofunctionality of peptides; therefore, proper selection of a method for the generation of active amino acids based on size, charge, and hydrophobicity is vital [ 6 ]. Various methods such as enzymatic hydrolysis [ 39 , 40 ], gastrointestinal digestion [ 39 ], microbial fermentation [ 6 , 12 , 39 , 41 , 42 ], germination [ 13 , 18 , 43 , 44 ], chemical modification [ 15 , 17 ], and membrane filtration [ 37 , 45 , 46 , 47 ] are employed to produce soy peptides or their mixtures. These methods help to produce enormous amounts of small peptides with antioxidant properties from soy protein [ 11 , 40 ].…”

Section: Production Characterization and Health Impact Of Soybeamentioning

confidence: 99%

“…Similarly, Nwachukwu and Aluko reported the considerable hydroxyl radical-scavenging ability of soybean protein hydrolysates and peptide fractions with a higher degree of hydrolysis (low molecular weight) [ 37 ]. In addition, the enhanced effect of fermented soybean meal, soy foods, and soymilk [ 41 , 48 , 49 , 50 ] against oxidative stress has been reported.…”

Section: Production Characterization and Health Impact Of Soybeamentioning

confidence: 99%

Health Benefits of Antioxidative Peptides Derived from Legume Proteins with a High Amino Acid Score

2021

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Legumes such as soybean, chickpea, lentil, cowpea, and mung bean, are valuable sources of protein with a high amino acid score and can provide bioactive peptides. This manuscript presents a review on legume-derived peptides, focusing on in vitro and in vivo studies on the potential antioxidative activities of protein hydrolysates and their characterization, amino acid sequences, or purified/novel peptides. The health implications of legume-derived antioxidative peptides in reducing the risks of cancer and cardiovascular diseases are linked with their potent action against oxidation and inflammation. The molecular weight profiles and amino acid sequences of purified and characterized legume-derived antioxidant peptides are not well established. Therefore, further exploration of legume protein hydrolysates is necessary for assessing the potential applications of antioxidant-derived peptides in the functional food industry.

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“…plantarum NJAU-01 strain significantly lowered protein carbonyl content in fermented sausage, as fermentation increased the antioxidant activity ( Hunaefi et al, 2013 ). Miri, Hajihosseini, Saedi, Vaseghi, and Rasooli (2019) reported the oxidation stress reduction of fermented soybean meal extract by Lactobacillus plantarum , through the increase in antioxidant activity.…”

Section: Resultsmentioning

confidence: 99%