Ferric hydroxide nanocage triggered Fenton-like reaction to improve amperometric immunosensor

Meng, Xuanze; Xu, Yang; Zhang, Nana; Ma, Bochen; Ma, Zhanfang; Han, Hongliang

doi:10.1016/j.snb.2021.129840

Cited by 12 publications

(3 citation statements)

References 34 publications

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Section: Type Of Peroxidase-active Nanozymesmentioning

confidence: 99%

“…Since it is an ionic compound with an incompact surface, molecule accessibility endowed it with excellent analytical performance including a wide linear range from 0.00001 to 100 U mL −1 and an ultralow detection limit of 0.785 U mL −1 . 81 Besides the representative iron-based oxygenated compounds mentioned above, other copper-based nanozymes including cuprous oxide, cuprous peroxide and copper hydroxide have also been reported to have peroxidase-like activity. [82][83][84] Li and co-workers have proposed a novel immunoprobe with excellent catalytic activity towards H 2 O 2 , which adopted cuprous oxidase as the framework and modified it with titanium dioxide and platinum-copper nanoparticles in sequence.…”

Section: Metal-based Oxygenated Compoundsmentioning

confidence: 99%

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Recent advances of peroxidase-active nanozymes in electrochemical immunoassays

Feng

yao

2023

Sens. Diagn.

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Section: Type Of Peroxidase-active Nanozymesmentioning

confidence: 99%

Section: Metal-based Oxygenated Compoundsmentioning

confidence: 99%

Recent advances of peroxidase-active nanozymes in electrochemical immunoassays

Feng

yao

2023

Sens. Diagn.

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“…The label-free electrochemical immunosensor is a newly developed novel detection method [ 13 , 14 , 15 , 16 ]. This type of immunosensor does not require the complex labeling of antigens or antibodies.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Immunoassay for Tumor Marker CA19-9 Detection Based on Self-Assembled Monolayer

et al. 2022

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A CA19-9 electrochemical immunosensor was constructed using a hybrid self-assembled membrane modified with a gold electrode and applied to detect real samples. Hybrid self-assembled membranes were selected for electrode modification and used to detect antigens. First, the pretreated working electrodes were placed in a 3-mercaptopropionic acid (MPA)/β-mercaptoethanol (ME) mixture for 24 h for self-assembly. The electrodes were then placed in an EDC/NHS mixture for 1 h. Layer modification was performed by stepwise dropwise addition of CA19-9 antibody, BSA, and antigen. Differential pulse voltammetry was used to characterize this immunosensor preparation process. The assembled electrochemical immunosensor enables linear detection in the concentration range of 0.05–500 U/mL of CA19-9, and the detection limit was calculated as 0.01 U/mL. The results of the specificity measurement test showed that the signal change of the interfering substance was much lower than the response value of the detected antigen, indicating that the sensor has good specificity and strong anti-interference ability. The repeatability test results showed that the relative standard deviations were less than 5%, showing good accuracy and precision. The CA19-9 electrochemical immunosensor was used for the actual sample detection, and the experimental results of the standard serum addition method showed that the RSD values of the test concentrations were all less than 10%. The recoveries were 102.4–115.0%, indicating that the assay has high precision, good accuracy, and high potential application value.

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In situ growth of electroactive polymers via ATRP to construct a biosensing interface for tumor marker

Wang

Han

et al. 2021

Microchim Acta

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Ferric hydroxide nanocage triggered Fenton-like reaction to improve amperometric immunosensor

Cited by 12 publications

References 34 publications

Recent advances of peroxidase-active nanozymes in electrochemical immunoassays

Recent advances of peroxidase-active nanozymes in electrochemical immunoassays

Electrochemical Immunoassay for Tumor Marker CA19-9 Detection Based on Self-Assembled Monolayer

In situ growth of electroactive polymers via ATRP to construct a biosensing interface for tumor marker

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