Ferrocenium Ion Confinement in Polyelectrolyte for Electrochemical Nitric Oxide Sensor

Abstract

Manuscript reports on ferrocenium ion entangled in polyelectrolyte matrix as a redox platform for oxidative and reductive sensing of nitric oxide (NO). It was prepared by oxidation of ferrocene in diethyl ether followed by extraction with polystyrene sulfonic acid (PSS) and Nafion® solution. The presence of stable ferrocenium cation was confirmed by FT-IR, UV-visible spectra, 1 HNMR and XRD. It results into a stable cyclic voltammogram in 100 mM Phosphate buffer, pH 7 solution with Ag/AgCl reference and Pt wire counter electrodes. The electrode sensitivity towards NO was confirmed through the increase in oxidative current at + 750 mV and reductive current at À 800 mV by the addition of 100 μL saturated NO solution. The chronoamperometric response for NO oxidation followed linearity in the concentration range of 200 nM to 3.5 μM. The lower detection limit and sensitivity were found to be 200 nM and be 33.29 μA/μM/cm 2 respectively. The reductive response also followed a linear trend in the concentration range of 100 μM to 1.2 mM with 15.15 μA/μM/cm 2 sensitivity and 100 μM detection limit. It indicates ferrocenium ion entanglement within polyelectrolyte matrix and its viability as a redox platform for oxidative as well as reductive sensing of nitric oxide.

Ferrocene Decorated N‐doped Carbon Modified Electrode with Enhanced Electrocatalytic Activity towards Non‐enzymatic Glucose Detection

“…The additional diffraction peak at 16.3° for FC‐S‐NDCN may due to the incorporation of FC into NDCN. Because of very trace amount of ferrocene content on NDCN surface to resolve the phase from observed peaks, the FC‐S‐NDCN material show low crystallinity behaviour (Figure 1) [29]. The morphology of FC‐S‐NDCN was analysed by HR‐TEM and SEM (Figure 2 & S1).…”

“…Herein, we have adopted a simple flame synthetic method to synthesise nitrogen doped carbon nanoparticles (NDCN) having high surface area as well as high porosity [28,29]. We have also established a novel synthetic route to prepare ferrocene decorated nitrogen doped carbon nanoparticles (FC-S-NDCN) without alkali treatment.…”

Polyelectrolytes Assembly: A Powerful Tool for Electrochemical Sensing Application

“…The above-mentioned suspension was placed on the surface of a GCE, and the prepared electrode was used for the amperometric determination of ascorbic acid. The stabilization of ferrocenium ions in various PE matrixes by ionic interaction and its application in NO detection was reported by Mathi et al [94]. The ferrocenium ions were prepared by the oxidation of ferrocene in diethyl ether, followed by extraction with a polystyrene sulphonic acid (PSS) or a Nafion ® solution.…”

“…The stabilization of ferrocenium ions in various PE matrixes by ionic interaction and its application in NO detection was reported by Mathi et al [94]. The ferrocenium ions were prepared by the oxidation of ferrocene in diethyl ether, followed by extraction with a polystyrene sulphonic acid (PSS) or a Nafion ® solution.…”

Recent Progress of Layer‐by‐layer Assembly, Free‐Standing Film and Hydrogel Based on Polyelectrolytes

“…The incorporation of redox molecules, such as ferrocene, into the polystyrene sulfonic acid matrix, allows nitric oxide redox detection. [ 71 ]…”