Fetal Doppler reference values in women with a normal body mass index

Abstract

Umbilical artery pulsatility index (UA PI), Middle cerebral artery pulsatility index (MCA PI), Cerebroplacental ratio (CPR), Body mass index (BMI)

Fetal cerebral blood‐flow redistribution: analysis of Doppler reference charts and association of different thresholds with adverse perinatal outcome

“…and of Arduini and Rizzo 19 . The chart of Dias et al 27 . had far higher CPR values (or lower UCR values) in the earlier gestational‐age range of 24–30 weeks, as compared with the other charts.…”

“…Figure 2b shows the median UCR values for all reference charts. There were two outliers: the charts of Dias et al 27 . and of Arduini and Rizzo 19 .…”

“…The OR values for an abnormal UCR or CPR varied from 1.7 to 2.7. However, the AUC of a ROC graph with the predicted probability for the composite adverse outcome was similar for all charts (0.71 to 0.73) 19,27 .…”

“…Three studies contained an algorithm for the median [22][23][24] . For four other studies gestational age dependent algorithms for the median were calculated from the published table data of the median [25][26][27][28] . Two studies published an algorithm for percentiles 2 2 , 2 4 .…”

“…All charts had a polynomial profile, except the Arduini chart which had a linear profile 19 . When Dias 27 and Arduini 19 charts were excluded, the range between the median values of UCR in the remaining eight charts was less than 0.1. Figure 4 shows a plot of the median values of CPR.…”