Few biomedical applications of carbon nanotubes

Yadav, Neelam; Tyagi, Manshi; Wadhwa, Shikha; Mathur, Ashish; Narang, Jagriti

doi:10.1016/bs.mie.2019.11.005

Cited by 17 publications

(4 citation statements)

References 43 publications

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“…CNTs are single or multi-layered seamless nanotube structures composed of carbon atoms that are classified into single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) according to the number of layers of carbon atoms [ 31 ]. The carbon atoms in CNTs mainly adopt sp 2 hybridization conferring excellent mechanical strength [ 32 ].…”

Section: Carbon Nanomaterialsmentioning

confidence: 99%

Multifunctional carbon nanomaterials for diagnostic applications in infectious diseases and tumors

et al. 2022

Materials Today Bio

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Section: Carbon Nanomaterialsmentioning

confidence: 99%

Multifunctional carbon nanomaterials for diagnostic applications in infectious diseases and tumors

et al. 2022

Materials Today Bio

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“…The adsorption method involves only a phase transfer of pollutants without degradation, the chemical oxidation method is unable to mineralize all organic substances, and biological treatment methods feature slow reaction rates and require the disposal of activated sludge. [9][10][11][12] Advanced oxidation processes (AOPs) have been widely used as an effective and environmentally friendly method to treat wastewater containing insecticides. In fact, radicals and intermediates such as OH • , O • À 2 , O • À , etc: À Á lead to the degradation of pollutants in the environment in this method via breaking chemical bonds based on matching their energy.…”

Section: Introductionmentioning

confidence: 99%

“…Each of the traditional wastewater treatment techniques, such as activated carbon adsorption, chemical oxidation, biological treatments, and so forth has limitations and disadvantages. The adsorption method involves only a phase transfer of pollutants without degradation, the chemical oxidation method is unable to mineralize all organic substances, and biological treatment methods feature slow reaction rates and require the disposal of activated sludge 9–12 . Advanced oxidation processes (AOPs) have been widely used as an effective and environmentally friendly method to treat wastewater containing insecticides.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a hybrid advanced oxidation process for removal of pirimicarb insecticide in aqueous media: Statistical optimization and estimation of electrical energy consumption

Ghavi,

Bagherian,

Rezaei‐Vahidian

2024

Env Prog and Sustain Energy

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In this paper, the role of periodate and persulfate as inorganic oxidants were studied in presence of ultraviolet radiation and titanium dioxide nanoparticles as a hybrid advanced oxidation photocatalytic processes for degradation and mineralization of the pirimicarb insecticide in aqueous media. The effects of several factors such as the ultraviolet irradiation, initial oxidant concentration, titanium dioxide nanoparticles dosage, and pH on the process performance were investigated. The process optimization was performed by the central composite design as a tools of response surface methodology for 30 mg L−1 of the insecticide initial concentration at 25°C and 10 min of degradation process. A degradation efficiency of about 86% and 85% have been obtained for the persulfate and periodate processes, respectively, in the optimum conditions. The mineralization efficiency of the process using persulfate and periodate were about 35% and 46% after 60 min, respectively. The kinetic studies show that both processes follow a pseudo‐first‐order kinetic model and the rate constants were 0.1483 min−1 for the persulfate and 0.1152 min−1 for the periodate process. Generally, it can be concluded that this method is suitable for the degradation and mineralization of toxic aromatic compounds.

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“…[ 16–19 ] Multiwalled carbon nanotubes (MWCNTs) are a class of CNTs that have been used widely in biomedical applications. [ 20–24 ] Since the size of MWCNTs is smaller than cellular organelles, they can enter the organelles. Hence, it is required to determine their toxicity before using them in biomedical applications.…”

Section: Introductionmentioning

confidence: 99%

In vitro comparative cytotoxic assessment of pristine and carboxylic functionalized multiwalled carbon nanotubes on LN18 cells

Vijayalakshmi

Sadanandan

Raghu

2022

J Biochem & Molecular Tox

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Multiwalled carbon nanotubes (MWCNTs) have been used in biomedical applications due to their ability to enter the cells. Carboxylic functionalization of MWCNT (MWCNT-COOH) is used to mitigate the toxicity of MWCNTs. Our study focuses on comparing the toxicity of MWCNT and MWCNT-COOH on the neuronal cells, LN18. Concentrations of 5, 10, 20, and 40 µg ml −1 were used for the study, and cytotoxicity was determined at 0, 1, 3, 6, 12, 24, and 48 h of incubation. Cell viability was assessed by Trypan Blue, MTT, and Live dead cell assays, and the oxidative stress produced was determined by reactive oxygen species (ROS) and Lipid peroxidation assays. MWCNT-COOH showed higher cell viability than MWCNT for 20 and 40 µg ml −1 at 24 and 48 h. This was also visually observed in the live dead cell imaging. However, at 48 h, the morphology of the cells appeared more stretched for all the concentrations of MWCNT and MWCNT-COOH in comparison to the control. A significant amount of ROS production can also be observed at the same concentration and time. Viability and oxidative stress results together revealed that MWCNT-COOH is less toxic when compared to MWCNT at longer incubation periods and higher concentrations. However, otherwise, the effect of both are comparable. A concentration of 5-10 µg ml −1 is ideal while using MWCNT and MWCNT-COOH as the toxicity is negligible. These findings can further be extended to various functionalizations of MWCNT for wider applications.

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Few biomedical applications of carbon nanotubes

Cited by 17 publications

References 43 publications

Multifunctional carbon nanomaterials for diagnostic applications in infectious diseases and tumors

Multifunctional carbon nanomaterials for diagnostic applications in infectious diseases and tumors

Evaluation of a hybrid advanced oxidation process for removal of pirimicarb insecticide in aqueous media: Statistical optimization and estimation of electrical energy consumption

In vitro comparative cytotoxic assessment of pristine and carboxylic functionalized multiwalled carbon nanotubes on LN18 cells

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