Fibres as functional foods and the effects on gut hormones: The example of β-glucans in a single arm pilot study

Baldassano, Sara; Accardi, Giulia; Aiello, Anna; Buscemi, Silvio; Miceli, Giuseppe Di; Galimberti, Damiano; Candore, Giuseppina; Ruisi, Paolo; Caruso, Calogero; Vasto, Sonya

doi:10.1016/j.jff.2018.05.059

Cited by 14 publications

(14 citation statements)

References 39 publications

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“…In a recent study, pasta enriched with 3% of Opuntia ficus-indica (OFI) extract, a plant known for its antioxidant and anti-inflammatory properties, was given to volunteers and beneficial effects were observed [64]. Similarly, pasta with beta-glucans as functional food has been investigated in a pilot study, demonstrating that its consumption could help in the prevention of age-related metabolic disorders [65].…”

Section: Discussionmentioning

confidence: 99%

Heat-Resistant Aphanizomenon flos-aquae (AFA) Extract (Klamin®) as a Functional Ingredient in Food Strategy for Prevention of Oxidative Stress

Nuzzo

Contardi

Kossyvaki

et al. 2019

Oxidative Medicine and Cellular Longevity

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Microalgae are generally considered an excellent source of vitamins, minerals, and bioactive molecules that make them suitable to be introduced in cosmetics, pharmaceuticals, and food industries. Aphanizomenon flos-aquae (AFA), an edible microalga, contains numerous biomolecules potentially able to prevent some pathologies including age-related disorders. With the aim to include an AFA extract (Klamin®) as a functional ingredient in baked products, we investigated if its bioactive molecules are destroyed or inactivated after standard cooking temperature. The AFA extract was exposed to heat stress (AFA-HS), and no significant decrease in pigment, polyphenol, and carotenoid content was detected by spectroscopic analysis. Thermal stability of AFA-HS extract was demonstrated by thermogravimetric analysis (TGA), and no change in the morphology of the granules of the powder was noticed by SEM microscopic observation. By Folin-Ciocalteu, ORAC, and ABTS assays, no change in the antioxidant activity and polyphenol contents was found after high-temperature exposition. When added in cell culture, solubilized AFA-HS lost neither its scavenging ability against ROS generation nor its protective role against Abeta, the main peptide involved in Alzheimer's disease. Prebiotic and antioxidant activities of AFA extract that are not lost after thermal stress were verified on E. coli bacteria. Finally, AFA-HS cookies, containing the extract as one of their ingredients, showed increased polyphenols. Here, we evaluate the possibility to use the AFA extract to produce functional food and prevent metabolic and age-related diseases.

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Section: Discussionmentioning

confidence: 99%

Heat-Resistant Aphanizomenon flos-aquae (AFA) Extract (Klamin®) as a Functional Ingredient in Food Strategy for Prevention of Oxidative Stress

Nuzzo

Contardi

Kossyvaki

et al. 2019

Oxidative Medicine and Cellular Longevity

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“…Inclusion and exclusion criteria are summarized in Table 1 . Briefly, during the first visit, the participants underwent anthropometric measurement and completed a habitual dietary intake assessment [ 20 ]. Before starting the activity, a blood sample (BASE) was collected; the second sample of blood was collected at the end of the 20 weeks (W20) ( Figure 1 ).…”

Section: Methodsmentioning

confidence: 99%

Is the Secret in the Gut? SuperJump Activity Improves Bone Remodeling and Glucose Homeostasis by GLP-1 and GIP Peptides in Eumenorrheic Women

Vasto

Amato

Proia

et al. 2022

Biology

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We showed that twenty weeks of SuperJump activity, an innovative workout training performed on an elastic minitrampoline, reduced bone resorption and increased bone formation in eumenorrheic women acting on the key points of the regulation of bone metabolism. The present study analyzed whether the gastrointestinal hormones are involved in the mechanism of action and if it has an impact on glucose homeostasis. The control group was composed of twelve women, similar to the exercise group that performed SuperJump activity for twenty weeks. The analysis was performed on blood samples and investigated GLP-1, GIP, GLP-2, PYY, ghrelin, glucose, insulin, insulin resistance, β-cell function, and insulin sensitivity. The results showed that the activity contributes to raising the GLP-1and GIP levels, and not on GLP-2, PYY, and ghrelin, which did not change. Moreover, SuperJump activity significantly reduced fasting insulin, glucose, insulin resistance, and increased insulin sensitivity but did not affect beta cell function. These data suggest that GLP-1, and GIP are involved in the mechanism of action that improves bone and glucose homeostasis following 20 weeks of SuperJump activity in eumenorrheic women.

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“…The latter, because osteopenia and osteoporosis during adulthood, seem to be related to the degree of bone mineralization during childhood and adolescence [ 10 ]. Adequate physical activity [ 11 ] and dietary habits with the supply of health-promoting substances is the basis of a healthy diet [ 12 , 13 ]. Therefore, correct dietary habits could be useful to maintain body weight and consequently improve body self-acceptance.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Body Perception, Preworkout Meal Habits and Bone Resorption in Child Gymnasts

Amato

Proia

Caldara

et al. 2021

IJERPH

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The beneficial effects of physical activity on body image perception and bone are debated among artistic gymnasts. Gymnasts seem to be at greater risk of developing body dissatisfaction, eating disorders and osteoporosis due to inadequate nutrition and attention to the appearance of the body. The objective of this work was to investigate the association between the artistic gymnast and a more favorable body image compared to their sedentary peers and if a preworkout high-carbohydrate meal (HCM; 300 kcal, 88% carbohydrates, 9% protein, 3% fat) or high-protein meal (HPM; 300 kcal, 55% carbohydrates, 31% protein, 13% fat) is able to attenuate bone resorption in young rhythmic gymnasts. Twenty-eight preadolescent female gymnasts were examined. Self-esteem tests were used to analyze body image perception. Preworkout eating habits were examined by short food frequency questions (FFQ) validated for children. The biomarker of the bone resorption C-terminal telopeptide region of collagen type 1 (CTX) was measured in the urine (fasting, postmeal and postworkout). Gymnasts reported higher satisfaction with their body appearance compared to sedentary peers. Of the gymnasts, 30% did not have a preworkout meal regularly, and the timing of the consumption was variable. Bone resorption was decreased by the HCM, consumed 90 min before the training, with respect to the HPM. The study suggests that playing artistic gymnastics is associated with a positive body self-perception in a child. The variability in preworkout meal frequency and timing need attention to prevent inadequate eating habits in light of the ability of the HCM to reduce acute bone resorption.

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Fibres as functional foods and the effects on gut hormones: The example of β-glucans in a single arm pilot study

Cited by 14 publications

References 39 publications

Heat-Resistant Aphanizomenon flos-aquae (AFA) Extract (Klamin®) as a Functional Ingredient in Food Strategy for Prevention of Oxidative Stress

Heat-Resistant Aphanizomenon flos-aquae (AFA) Extract (Klamin®) as a Functional Ingredient in Food Strategy for Prevention of Oxidative Stress

Is the Secret in the Gut? SuperJump Activity Improves Bone Remodeling and Glucose Homeostasis by GLP-1 and GIP Peptides in Eumenorrheic Women

Analysis of Body Perception, Preworkout Meal Habits and Bone Resorption in Child Gymnasts

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