1990
DOI: 10.1046/j.1537-2995.1990.30891020337.x
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Fibrin glue: the perfect operative sealant?

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Cited by 249 publications
(126 citation statements)
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“…The rate of FG degradation can be regulated by modulating the concentration of fibrinogen or adding aprotinin. For these reasons, FG is an excellent supporting material for seed cells in tissue engineering, [39][40][41] and particularly for ANFH, which may require added support for transplanted BMSCs. When HGF-transgenic BMSCs are mixed with FG in an appropriate proportion, the gel structure formed also functions as a sponge-like drug vehicle that could release secreted HGF protein slowly and maintain a desired local concentration.…”
Section: Discussionmentioning
confidence: 99%
“…The rate of FG degradation can be regulated by modulating the concentration of fibrinogen or adding aprotinin. For these reasons, FG is an excellent supporting material for seed cells in tissue engineering, [39][40][41] and particularly for ANFH, which may require added support for transplanted BMSCs. When HGF-transgenic BMSCs are mixed with FG in an appropriate proportion, the gel structure formed also functions as a sponge-like drug vehicle that could release secreted HGF protein slowly and maintain a desired local concentration.…”
Section: Discussionmentioning
confidence: 99%
“…Two transplants were sometimes needed to cover the entire surface of a large defect. The graft was fixed with fibrin glue (Tissucol R , Immuno, Vienna) [14]. The perichondrial graft was placed on the subchondral bone with the chondral side facing the joint; it was firmly pressed to the underlying bone with a wet gauze for one minute, and the knee then moved to assess its fixation.…”
Section: Operative Techniquementioning
confidence: 99%
“…Karaciğer ve dalak cerrahisinde kullanımının kanama kontrolündeki etkisi gösteril-miştir. [9][10][11][12][13] Ankaferd Blood Stopper ® (ABS) son yıllarda klinik kullanıma giren, bitkisel kökenli, topikal hemostatik ajandır. Hemostazı, kanama pıhtılaşma faktörle-rinden bağımsız olarak, enkapsüle protein ağı ile fokal eritrosit agregasyonunu sağlayarak gerçekleştirir.…”
Section: Resultsunclassified
“…Ameliyat süresinin kısalması için, kanamanın kontrolünde topikal hemostatiklerin kullanımı da cerraha avantaj sağlayabilir Günümüz-de Japonya'da topikal hemostatiklerin karaciğer cerrahisinde standart bir endikasyon olmadan kullanımı %60'a kadar çıkmıştır. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] Bu ajanların seçiminde cerrahın tercihi kadar, hemostatik materyalin yapısı, kanamanın ciddiyeti, acil ya da elektif cerrahi yaklaşımlar gibi faktörler oynar. Fiyat, uygulama kolaylığı ve muhafaza edilme özellikleri de seçimi etkilemektedir.…”
Section: Discussionunclassified