Fibrin Sealant in Pediatric Surgery

Gdanietz, K; Gutsche, I.

doi:10.1007/978-3-642-85101-8_21

Cited by 3 publications

(4 citation statements)

References 5 publications

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“…Its spectrum of indications has increased steadily since then. Its applications have also been gradually augmented in various surgical areas, including trauma, minimally invasive surgery, urological, plastic and reconstructive, neurological, thoracic, gastrointestinal, and head and neck surgery, and as an adjuvant in treating burns in children [13,14,[18][19][20][21][22][23].…”

Section: Discussionmentioning

confidence: 99%

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Role of Fibrin Glue in the Prevention of Cervical Leakage and Strictures After Esophageal Reconstruction of Caustic Injury

et al. 2009

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Section: Discussionmentioning

confidence: 99%

“…Fibrin sealant was introduced into pediatric surgery in 1981 to seal spleen ruptures, and most indications are related to its recognized hemostatic function [21]. Its spectrum of indications has increased steadily since then.…”

Section: Discussionmentioning

confidence: 99%

Role of Fibrin Glue in the Prevention of Cervical Leakage and Strictures After Esophageal Reconstruction of Caustic Injury

et al. 2009

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“…Biological glues that are concentrates of coagulation factors are well known not only for their adhesion and coagulation properties, but also for their ability to promote healing and to attenuate the virulence of pathogens. They are regularly used in most surgical specialties, in both adults (4–6) and children (7).…”

Section: Discussionmentioning

confidence: 99%

Fibrin Glue is Useful in Preventing Early Dialysate Leakage in Children on Chronic Peritoneal Dialysis

et al. 2004

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Objective To assess if application of fibrin glue sealant to the peritoneal cuff suture is useful in the prevention of early dialysate leakage in children with end-stage renal disease on chronic peritoneal dialysis (CPD). Design Single-center, open-label, prospective randomized study. Setting University Pediatric Hospital. Methods 52 catheters were implanted in 45 children (mean age 6.2 ± 4.5 years). Catheters were randomly assigned to either the control group or the sealant group. In the latter group, 1 mL of fibrin glue sealant was applied to the peritoneal cuff suture. 18 catheters were used for the first time within 5 days after implantation (early-used catheters). Leakage, exit-site or tunnel infection, peritonitis, and adverse secondary effects were evaluated during the initial 60 days after implantation. Results No adverse secondary effects were seen after the application of the fibrin glue sealant. The incidence of exit/tunnel infection and peritonitis was similar in the two groups. The incidence of leakage was significantly lower in the sealant group ( p < 0.02). In the early-used catheters, leakage was detected in 9% of the catheters in the sealant group and in 57% of the control group ( p < 0.05). Conclusions The application of 1 mL of fibrin glue to the peritoneal cuff suture prevented early dialysate leakage without secondary adverse effects in children on CPD.

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“…Since then, the spectrum of indications has been gradually enlarged. Today it is commonly used in pediatric urology for hypospadias surgery and ureteropelvic junction operation (4). The goal of our study is to compare the testicular histological changes caused by fibrin glue and other suture materials in prepubertal rats undergoing transparenchymal fixation.…”

Section: Introductionmentioning

confidence: 99%

Testis Fixation in Prepubertal Rats: Fibrin Glue Versus Transparenchymal Sutures Reduces Testicular Damage

Şencan

Genç²,

Günşar³

et al. 2004

Eur J Pediatr Surg

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Experimental studies have shown that different suture materials used in testis fixation cause some degree of inflammation in the testis. This study was planned to compare the histological changes that were caused by fibrin glue which is a tissue sealant and by silk and polypropylene for transparenchymal testis fixation. 28 prepubertal rats were divided into 4 groups. Testis was fixed to the tunica vaginalis by fibrin glue in group 1, by silk in group 2 and by polypropylene in group 3. Group 4 was planned as a control. Testicular inflammation and seminiferous tubular diameter were evaluated for histological changes. The least inflammation was observed in the fibrin glue group, while the most inflammation occurred in the silk group. Seminiferous tubular diameter was 241.55 +/- 45.90 in the fibrin glue group, 151.90 +/- 8.34 in the silk group and 161.36 +/- 9.96 in the polypropylene group. In conclusion, fibrin glue, when used for testis fixation, causes less inflammation and less destruction of seminiferous tubular diameter compared with silk and polypropylene.

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Fibrin Sealant in Pediatric Surgery

Cited by 3 publications

References 5 publications

Role of Fibrin Glue in the Prevention of Cervical Leakage and Strictures After Esophageal Reconstruction of Caustic Injury

Role of Fibrin Glue in the Prevention of Cervical Leakage and Strictures After Esophageal Reconstruction of Caustic Injury

Fibrin Glue is Useful in Preventing Early Dialysate Leakage in Children on Chronic Peritoneal Dialysis

Testis Fixation in Prepubertal Rats: Fibrin Glue Versus Transparenchymal Sutures Reduces Testicular Damage

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