Fibromatosis of the breast: A pictorial review of the imaging and histopathology findings

Ebrahim, Lamya; Parry, Jeremy; Taylor, Donna

doi:10.1016/j.crad.2014.05.105

Cited by 43 publications

(47 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Fibromatosis in the breast parenchyma manifests as a spiculated mass and is rarely accompanied by calcification [1,4,10,18]. However, implant-associated fibromatosis is reported to have a different appearance from breast parenchymal fibromatosis.…”

Section: Discussionmentioning

confidence: 94%

Breast fibromatosis associated with breast implants

et al. 2015

View full text Add to dashboard Cite

Fibromatosis refers to an extra-abdominal desmoid tumor or aggressive fibromatosis. Breast fibromatosis can develop in association with the capsule around a breast implant, although reports of cases of fibromatosis associated with breast implants are rare. As the demand for breast augmentation has increased, it is important to understand the diseases associated with breast implants. In the present report, we describe a case of breast fibromatosis that developed adjacent to a breast implant and demonstrated a relatively well-defined border even though it invaded the surrounding structures. We also explore the specific imaging features for diagnosing breast fibromatosis in association with implants by reviewing previous literature.

show abstract

Section: Discussionmentioning

confidence: 94%

Breast fibromatosis associated with breast implants

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Pain is often a finding in advanced disease when the chest wall is involved. Core needle biopsy can be used to support the diagnosis; however, the finding of a spindle cell proliferation may be very nondiagnostic, often yielding indeterminate or unclear spindle cell pathologies . This often leads to high positive margin rate with preoperative diagnosis such as a fibroadenoma, myofibroblastoma, or spindle cell lesion; thus, wide margins were not planned for at the initial operation.…”

Section: Resultsmentioning

confidence: 99%

“…This often leads to high positive margin rate with preoperative diagnosis such as a fibroadenoma, myofibroblastoma, or spindle cell lesion; thus, wide margins were not planned for at the initial operation. Breast MRI or CT scan of the chest is useful imaging modalities for preoperative planning and to understand the extent of chest wall involvement (Figure ). Fibromatosis should also be considered in cases of an atypical abscess, as it is the great mimicker; ultrasound features of a heterogeneous echoic mass with an internal anechoic area should prompt further evaluation …”

Section: Resultsmentioning

confidence: 99%

“…As far as medical treatment of fibromatosis, this should be reserved for those with unresectable disease or the presence of persistently positive margins. Hormonal therapy with tamoxifen has been described with some success in several series (up to 20% of tumors responding) . There has also been some success with tyrosine kinase inhibitors such as imatinib .…”

Section: Resultsmentioning

confidence: 99%

“…Hormonal therapy with tamoxifen has been described with some success in several series (up to 20% of tumors responding) . There has also been some success with tyrosine kinase inhibitors such as imatinib . However, these treatments have limited efficacy and take several months for the tumor to have a response .…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Breast fibromatosis: Making the case for primary vs secondary subtypes

et al. 2019

View full text Add to dashboard Cite

Fibromatosis of the breast is a rare condition that can be locally aggressive. The mainstay of treatment remains wide local excision, with varied adjuvant therapy as needed. The authors describe their experience in the treatment of a series of patients and propose the classification of primary and secondary breast fibromatosis. A single‐institution retrospective analysis of patients treated for breast fibromatosis from 2003 to 2017 was completed. Demographic data, pertinent past medical history, and treatment modalities were reviewed. Primary breast fibromatosis was defined as arising in the absence of previous surgery or radiation therapy to the ipsilateral breast. Secondary breast fibromatosis was defined as arising in the setting of previous surgery or radiation therapy to the ipsilateral breast. A total of 16 patients were included with the median age 40 (28‐64) years. The average size of the lesion was 6.37 cm (range of 1.5‐15 cm). Mean follow‐up time was 65 months. Surgical excision was completed in 14 patients, with two recurrences. There were no recurrences in patients with surgical margins >1 cm. Two patients were treated nonsurgically. There were seven patients with primary fibromatosis of the breast and nine patients with secondary fibromatosis of the breast. Fibromatosis of the breast is difficult to diagnose prior to surgical excision. We advocate for the multi‐disciplinary treatment of this disease process with an aggressive surgical approach to achieve margins >1 cm.

show abstract

Ultrasound characteristics of breast fibromatosis mimicking carcinoma

Su,

Huang,

et al. 2023

J of Clinical Ultrasound

View full text Add to dashboard Cite

PurposeTo explore the value of ultrasound (US) characteristics in diagnosing breast fibromatosis (BF) and evaluate their differences from breast carcinoma.MethodsA total of 121 patients with BF (n = 24, 29 lesions) or invasive ductal carcinoma (IDC) (n = 97, 102 lesions) of the breast were included. Their clinical and US findings were recorded and analyzed.ResultsThe mean age of BF was younger than that of IDC (28.75 ± 5.55 vs. 50.19 ± 9.87, p < 0.001). The mean size of the BF was smaller than that of IDC (2.09 ± 0.91 vs. 2.71 ± 1.20, p = 0.011). Compared to IDC, BF had more frequency of posterior echo attenuation (p < 0.001), less frequency of peripheral hyperechoic halo (p = 0.002), calcification (p = 0.001), US reported axillary lymph node positive (p = 0.025), and grade 2–3 vascularity (p < 0.001). The Breast Imaging Reporting and Data System categorized BF at a lower level than IDC (p < 0.001). After adjusting for age, the peripheral hyperechoic halo, posterior echo feature, and vascularity could independently identify the differences between these two entities.ConclusionSome differences were observed between BF and IDC in terms of patient age, lesion size, and US characteristics.

show abstract

Fibromatosis of the breast: A pictorial review of the imaging and histopathology findings

Cited by 43 publications

References 19 publications

Breast fibromatosis associated with breast implants

Breast fibromatosis associated with breast implants

Breast fibromatosis: Making the case for primary vs secondary subtypes

Ultrasound characteristics of breast fibromatosis mimicking carcinoma

Contact Info

Product

Resources

About