Fibrossarcoma epitelióide esclerosante: relato de caso.

Borba, P; Fiod, Nelson Jabour; Gouveia, Gustavo; Nascimento, Marilene F.; Rezende, José Francisco de

doi:10.32635/2176-9745.rbc.2003v49n4.2075

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…Pelas análises macro e microscópicas do caso relatado e dos estudos acerca do fibrossarcoma é possível sugerir que o paciente em questão apresentava uma forma primária desta patologia, provavelmente aderida ao periósteo, de acordo com a localização anatômica em que a massa foi identificada (Borba et al, 2003). Macroscopicamente, apresenta coloração branco acinzentado, semelhante a descrição feita por Thomson (1990).…”

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Fibrosarcoma in Rottweiler dog: case report

Carneiro¹,

Quintana²,

Andrade³

et al. 2020

Pubvet

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The present study aims to report a case of fibrosarcoma in an elderly canine patient who underwent necroscopic examination in June 2018 after natural death. Macroscopic and microscopic analyzes of the pathological findings were performed by organ visualization and histopathological processing of the collected samples. Macroscopically, a pelvic tumor mass of approximately 15 cm, cardiac hypertrophy with parasites in the ventricular lumen, congested and nodular lungs, hepatomegaly and renal atrophy were observed. Histological analysis of the primary tumor mass was compatible with a fibrosarcoma, with most cells of fusiform morphology, with foci of hemorrhage and necrosis in the center of the tumor, alternating with regions of desmoplastic reaction, nuclear atypia and prominent nucleoli. Also, microscopy revealed swollen pulmonary parenchyma with diffuse hemorrhage, vascular congestion, thickening of the alveolar septa and pulmonary nodules suggestive of metastatic lesions, as well as liver with congested sinus capillaries and diffuse hemorrhage in the hepatic parenchyma with foci of coagulation necrosis. Fibrosarcoma is a tumor of mesenchymal origin, composed of transformed fibroblasts, in a collagen background. It occurs in all species, but is more common in dogs and cats. In dogs, it usually manifests in solitary form and in older individuals, with a mean age of 9.7 years. Most pathologists describe the histological picture of fibrosarcoma as a fishbone pattern. It is usually a very invasive tumor, making surgical treatment difficult because it does not allow a wide margin of excision, and its clinic manifests itself late, making diagnosis and treatment even more difficult, as in the case reported here, in which the patient suddenly died. Thus, histopathological and cytopathological analysis remain the gold standard among the initial diagnostic methods to confirm the presence of the tumor, highlighting the importance of applying these study methods in determining the morphological characteristics of different types of lesions, as well as their forms, whose diagnosis can be confirmed with other diagnostic methods.

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Section: Discussionunclassified

Fibrosarcoma in Rottweiler dog: case report

Carneiro¹,

Quintana²,

Andrade³

et al. 2020

Pubvet

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Nodular fasciitis on the zygomatic region: a rare presentation

Souza¹,

Rochael

Farias

et al. 2013

An. Bras. Dermatol.

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Nodular fasciitis is a benign tumor, resulting from reactive proliferation composed of fibroblastic/myofibroblastic cells. Due to its rapid growth and high cellularity it may be mistaken for sarcoma. Despite the possibility of spontaneous regression, excision is the treatment of choice. A 24-year-old female patient presented with a nodule on the zygomatic region with 3 months of evolution. Excisional biopsy was performed. Histopathological examination associated with immunohistochemical markers HHF35, AML and Ki-67 allowed diagnostic confirmation. The main relevance of the case presented is its rare location, suggesting its inclusion among the differential diagnoses of tumor lesions on the face.

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Fibrossarcoma epitelióide esclerosante: relato de caso.

Cited by 2 publications

References 5 publications

Fibrosarcoma in Rottweiler dog: case report

Fibrosarcoma in Rottweiler dog: case report

Nodular fasciitis on the zygomatic region: a rare presentation

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