Fibrous cephalic plaques in tuberous sclerosis complex

Abstract

Two-fifths of FCPs presented on the forehead, with most of the remainder in other locations on the face and scalp. Better recognition of these lesions may lead to earlier diagnosis of TSC.

The cutaneous manifestations of tuberous sclerosis complex

“…These plaques can also be found in other craniofacial areas. Oyerinde et al (2018) demonstrated in an observational cohort study that 39% of FCPs were found on the forehead, 31% on the scalp, 27% on the face (non-forehead), and 3% on the neck. These characteristic lesions are found in approximately 25% of TSC patients (Jóźwiak et al, 1998;Webb et al, 1996).…”

“…As FCPs are histologically similar to angiofibromas, these lesions are considered as a single major criterion for TSC Roach et al, 1998). Oyerinde et al (2018) demonstrated in an observational cohort study that 39% of FCPs were found on the forehead, 31% on the scalp, 27% on the face (non-forehead), and 3% on the neck. FCPs typically occur on the forehead of TSC patients (Oyerinde et al, 2018).…”

“…Furthermore, FCPs are a major feature of the TSC criteria in light that these lesions may represent the most specific skin finding of TSC. FCPs typically occur on the forehead of TSC patients (Oyerinde et al, 2018). These plaques can also be found in other craniofacial areas.…”

Participation of a Primary Pediatrician in the Early Diagnostics and Treatment of Tuberous Sclerosis in Children

“…Фиброзные бляшки имеют бежевый цвет, они шероховатые на ощупь и несколько выступают над окружающей кожей. Размер и число бляшек может варьировать [3,4,14,15,18].…”

“…Количество участков «шагреневой кожи» вариабельно, но чаще они бывают единичными. Размер их колеблется от 1 до 10 см и более [3,4,14,15,18].…”