Fibrous hamartoma of infancy

Maung, Raymond; Lindsay, Richard; Trevenen, Cynthia; Hwang, Wen-Zern

doi:10.1016/s0046-8177(87)80367-2

Cited by 19 publications

(16 citation statements)

References 8 publications

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“…5 Although the shoulder girdle area and upper arm are the favored locations, FH may occur anywhere in the body. [6][7][8] The most common site of the lesion in our series, as in others 5,9 was the upper arm (Fig 1). Most of the lesions are usually small, although masses as large as 10 cm have been reported.…”

Section: Discussionsupporting

confidence: 62%

“…Generally no other radiologic investigations are recommended. 8 The main diagnostic problem for these lesions concerns the differential diagnosis with other soft tissue masses, which require a different clinical and therapeutic approach. Fine-needle aspiration biopsy may be an useful tool in recognizing the myofibroblastic nature of the lesion, 12 but only histology can disclose the typical organoid pattern that is a clue to the diagnosis, together with the immature mesenchymal component (Fig 2).…”

Section: Discussionmentioning

confidence: 99%

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Fibrous hamartoma of infancy: An Italian multi-institutional experience

Carretto

Dall’Igna

Alaggio

et al. 2006

Journal of the American Academy of Dermatology

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Section: Discussionsupporting

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Fibrous hamartoma of infancy: An Italian multi-institutional experience

Carretto

Dall’Igna

Alaggio

et al. 2006

Journal of the American Academy of Dermatology

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“…Lesions up to 20 cm in diameter have been reported [6], however more commonly they range from 1 to 8 cm. The lesion is most frequently singular, however synchronous and metachronous lesions have been reported [8,10,15]. Surgical excision is the treatment of choice with cure being achieved by a combination of sub-total and repeat excisions as necessary to avoid disfiguring surgeries [2].…”

Section: Discussionmentioning

confidence: 99%

Benign fibrous hamartoma of infancy: a case of MR imaging paralleling histologic findings

2014

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Fibrous hamartoma of infancy is a rare fibrous tumor of the subcutaneous tissue in infants. While most case reports focus on the unique histologic appearance, which has traditionally been relied upon for diagnosis, there are few reports in the radiology literature of its appearance at MR imaging. In this report, the authors present the case of a 9-month-old male who presented with a soft tissue mass on the shoulder. The MRI findings in benign fibrous hamartoma of infancy parallel the three components of the lesion seen histologically, with an organized arrangement of fat interspersed among heterogeneous soft tissue bands composed of mesenchymal and fibrous tissue. When present, this characteristic appearance may allow the diagnosis to be suggested preoperatively.

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“…Table II, Table IV and Table V. 12,13,[22][23][24][25][26][27][28][29] Table IV and Table V outline the clinical and histologic features that can be used to differentiate among FHI, IMF, and soft tissue sarcomas, namely fibrosarcoma. It should be noted that generalized IMF is a unique subtype of multicentric IMF with visceral involvement.…”

Section: Discussion and Review Of The Literaturementioning

confidence: 99%

“…It should be noted that generalized IMF is a unique subtype of multicentric IMF with visceral involvement. 12,13,[22][23][24][25] No clear familial or syndromic association has been reported with FHI 2 ; however, genetic linkage to Williams syndrome (WS) has been reported. WS is a developmental disorder involving the cardiovascular and central nervous systems.…”

Section: Discussion and Review Of The Literaturementioning

confidence: 99%