Fibrous poly(chitosan-g-dl-lactic acid) scaffolds prepared via electro-wet-spinning

Wan, Ying; Cao, Xiaoying; Zhang, Shengmin; Wang, Sheng; Wu, Qingyin

doi:10.1016/j.actbio.2008.01.001

Cited by 49 publications

(28 citation statements)

References 50 publications

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“…The HTCSC/PVA nanofiber mats have a good antibacterial activity against Staphylococcus aureus and Escherichia coli. Poly(chitosan-g-DL-lactic acid)(P(CS-g-LA)) copolymers which were produced by grafted DL-lactic acid onto chitosan were spun into submicron and/or nanofibers to fabricate scaffolds using an electrowet-spinning technique [84]. The diameter of the fibers in different scaffolds could vary from about 100 nm to around 3 µm.…”

Section: Electrospinning Of Chitosan Derivativesmentioning

confidence: 99%

Preparations, properties and applications of chitosan based nanofibers fabricated by electrospinning

Sun¹,

Li²

2011

Express Polym. Lett.

218

101

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Chitosan is soluble in most acids. The protonation of the amino groups on the chitosan backbone inhibits the electrospinnability of pure chitosan. Recently, electrospinning of nanofibers based on chitosan has been widely researched and numerous nanofibers containing chitosan have been prepared by decreasing the number of the free amino groups of chitosan as the nanofibiers have enormous possibilities for better utilization in various areas. This article reviews the preparations and properties of the nanofibers which were electrospun from pure chitosan, blends of chitosan and synthetic polymers, blends of chitosan and protein, chitosan derivatives, as well as blends of chitosan and inorganic nanoparticles, respectively. The applications of the nanofibers containing chitosan such as enzyme immobilization, filtration, wound dressing, tissue engineering, drug delivery and catalysis are also summarized in detail

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Section: Electrospinning Of Chitosan Derivativesmentioning

confidence: 99%

Preparations, properties and applications of chitosan based nanofibers fabricated by electrospinning

Sun¹,

Li²

2011

Express Polym. Lett.

218

101

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“…As mentioned earlier, such hybrid scaffolds are expected to demonstrate improved mechanical properties over those made from the natural polymer only. According to previous studies, chitosan nanofibers undergo a sharp decrease in mechanical strength and Young's modulus when hydrated [41]. This property limits their biomedical application, given that specimens are kept in culture and/ or implanted in the body.…”

Section: Discussionmentioning

confidence: 99%

“…This increase could be a result of the longitudinal shrinkage of ~30% that was seen after PVA extraction; the increase provides an advantage for the PLGA/CH scaffold over chitosan nanofibrous scaffolds, which show only very little elongation at the break [41,42]. Taken together, our findings suggest that, given its improved mechanical properties when compared to chitosan nanofibers and strength similar to that of our PLGA scaffold, the hybrid PLGA/CH scaffold can be considered an appropriate candidate for biomedical and tissue engineering applications.…”

Section: Discussionmentioning

confidence: 99%

Investigation of Human Mesenchymal Stromal Cells Cultured on PLGA or PLGA/Chitosan Electrospun Nanofibers

Ajalloueian¹

2015

J Bioprocess Biotech

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“…The response of deposited protein films to calcium ions was monitored as the biological activity of the films 12) implant coatings. Nanofibers of DNA, hyaluronic acid, citrosan, poly(lactic acid) or other synthetic polymers were also prepared by the ESD technique [14][15][16][17] .…”

Section: The Electrospray Deposition (Esd) Methods Is a Technique Thatmentioning

confidence: 99%

Collagen Nanofiber on Titanium or Partially Stabilized Zirconia by Electrospray Deposition

Hayakawa

Yoshinari

Nitta

et al. 2010

J. Hard Tissue Biology.

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The present study demonstrated collagen nanofiber deposition onto titanium and partially stabilized zirconia, yttria-stabilized zirconia (Y-TZP), using an electrospray deposition (ESD) technique. Type I collagen was dissolved into 1,1,1,2,2,2-hexafluoro-2-propanol at different concentrations. The effects of the flow rate of the collagen solution and the applied voltage on collagen nanofiber deposition were investigated.For titanium substrates, a collagen concentration of 50 mg/ml, a flow rate of 5.0 µl/min, and an applied voltage of 16 kV were found to be suitable for the deposition of uniform collagen nanofibers. Collagen nanofibers could be sprayed onto Y-TZP, which is not an electrically conductive substrate, although nanofibers fused during ESD. To avoid the fusion of nanofibers, titanium sputter-coating was performed on Y-TZP. Less fusion of collagen fibers occurred. A collagen concentration of 50 mg/ml, a flow rate of 5.0 µl/min, and an applied voltage of 25 kV were found to be appropriate for the deposition of uniform collagen nanofibers onto titanium sputter-coated Y-TZP. The ESD technique was shown to be effective for the deposition of collagen nanofibers.

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Fibrous poly(chitosan-g-dl-lactic acid) scaffolds prepared via electro-wet-spinning

Cited by 49 publications

References 50 publications

Preparations, properties and applications of chitosan based nanofibers fabricated by electrospinning

Preparations, properties and applications of chitosan based nanofibers fabricated by electrospinning

Investigation of Human Mesenchymal Stromal Cells Cultured on PLGA or PLGA/Chitosan Electrospun Nanofibers

Collagen Nanofiber on Titanium or Partially Stabilized Zirconia by Electrospray Deposition

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