2012
DOI: 10.1364/josaa.29.001367
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Field-matter integral overlap to estimate the sensitivity of surface plasmon resonance biosensors

Abstract: We have analyzed the effectiveness of field-matter integral overlap between target index distribution and local near-fields to assess detection sensitivity of surface plasmon resonance (SPR) biosensors. The correlation of the overlap with sensitivity was clear. An overlap integral defined with lateral electric field intensity produced the highest correlation due to tangential continuity across a boundary. Among the three detection scenarios considered, the correlation for localized SPR sensing was slightly low… Show more

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Cited by 37 publications
(16 citation statements)
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References 45 publications
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“…overlap volume [31]. The reflectivity from proposed multilayer system is proportional to this overlap volume and accordingly the sensitivity of SPR sensor is proportional to overlap integral [31]. The sensitivity of the sensor increases whenever there is increase in numerical value of overlap integral.…”
Section: Resultsmentioning
confidence: 98%
“…overlap volume [31]. The reflectivity from proposed multilayer system is proportional to this overlap volume and accordingly the sensitivity of SPR sensor is proportional to overlap integral [31]. The sensitivity of the sensor increases whenever there is increase in numerical value of overlap integral.…”
Section: Resultsmentioning
confidence: 98%
“…Figure 4 displays the vertical intensity profiles at the point where maximum field of E X is found. We note that among three nonzero field components of E X , H Y , and E Z for TM-polarization, the highest correlation between the matter-field overlap and the sensor sensitivity was obtained with the intensity of E X [20]. Hence, we provide only E X field for direct comparison with the sensitivity.…”
Section: Resultsmentioning
confidence: 99%
“…Note that the absorbed power is similar to overlap integrals between electromagnetic fields and target molecules used to represent detection sensitivity [21]. Absorption cross-section is then calculated as dividing P abs by incident field intensity.…”
Section: Methodsmentioning
confidence: 99%