Field Trials of an Oral Calcium Propionate Paste as an Aid to Prevent Milk Fever in Periparturient Dairy Cows

Goff, Jesse P.; Horst, Ronald L.; Jardon, P.W.; Borelli, C.; Wedam, J.

doi:10.3168/jds.s0022-0302(96)76375-0

Cited by 84 publications

(69 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Sustained levels of calcium in serum for the initial 6 h may be explained by the slow gastrointestinal absorbance of the calcium propionate constituent of the DR formula (Goff and Horst 1994). Goff et al (1996) reported higher levels of calcium 12 h after treatment in cows supplemented with two doses of calcium pro pionate at calving and 12 h later. Our data showed that a single dose of calcium propionate 12 h after calving was sufficient to increase calcium concentrations for at least 12 h. Although, there was not a clear effect after treatment administration, lower values of phosphorous in cows supplemented with DR ( Figure 1C) may be a homeostatic response after increased concentrations of calcium.…”

Section: Resultsmentioning

confidence: 99%

“…The acute increase of NEFA values at calving are associated with fat mobilization consequence of decreased DMI and increased NEB before parturition (Grummer 1993, Gerloff andHerdt 1999). Previous studies have supplemented propylene glycol for more than10 days during pre-partum in order to increase glycemia and subsequently reduce NEFA levels during transition period (Studer et al 1993, Grummer et al 1994, Goff et al 1996, Stockes and Goff 2001. However, this data indicate that a single day supple mentation is insufficient to reduce fat mobilization and consequent NEFA levels in cows under NEB.…”

Section: Resultsmentioning

confidence: 99%

“…calving and 12 h after calving has been shown to reduce the number of cows suffering from subclinical hypocalcemia Lactating dairy cows undergo important changes in (Goff et al 1996). Propionate plays a major glucogenic energy and mineral metabolism during the transition effect as a volatile fatty acid in the rumen and can decrease period corresponding from the last three weeks of gesbeta-hydroxy butyrate (BHB) and non-esterified fatty tation until the first three weeks post-partum (Grummer acids (NEFA) during the first 2 days post-partum (Goff 1993).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Supplementing transition cows with calcium propionate-propylene glycol drenching or organic trace minerals: implications on reproductive and lactation performances

Peralta¹,

Monardes

Duchens

et al. 2011

Arch. med. vet.

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Supplementing transition cows with calcium propionate-propylene glycol drenching or organic trace minerals: implications on reproductive and lactation performances

Peralta¹,

Monardes

Duchens

et al. 2011

Arch. med. vet.

View full text Add to dashboard Cite

“…Waldo & Schultz (1960) concluded that the hyperglycemic effect of PG was a consequence, for the most part, of its intact absorption and, to a lesser extent, of the production of propionic acid, and therefore it was an excellent alternative for treating clinical cases of ketosis. Goff et al (1996), supplying calcium propionate at calving and after 12 hours, observed a smaller concentration of NEFA 24 hours after calving in Jersey cows, but not in Holstein cows. However, its application reduced the occurrence of milk fever and subclinical hypocalcemia in both breeds, in herds where those problems occurred.…”

Section: Resultsmentioning

confidence: 99%

Gluconeogenic supplements do not affect production, reproductive traits and blood metabolite of holstein cows during the transition period

Oliveira

Pires

Meyer

et al. 2004

Sci. agric. (Piracicaba, Braz.)

View full text Add to dashboard Cite

The use of gluconeogenic supplements for dairy cows during the transition period has produced contradictory responses in the literature, making it difficult to recommend them. The objective of this trial was to evaluate supplementation with propylene glycol (PG), calcium propionate (CP), and "Dairy Power Drench ® " (DR) on the transitional period of Holstein cows. Parameters studied were variation of body condition score (BCS), body weight (BW), milk production (MP), reproductive efficiency and nonesterified fatty acid concentration (NEFA). One hundred and sixty five animals from two commercial herds were used. Treatments consisted of: C-Control; DR-administration of "Dairy Power Drench ® " (3 applications) during postpartum; CP-daily administration of calcium propionate (500 g); PG-daily administration of propylene glycol (500 mL). Variation sources studied were the effect of treatments and blocks as function of farm and parity. No interaction between time (weeks) and treatments, or treatment effects, were found for BCS. However, there was a quadratic effect of time. Body weight and its variation were not affected by treatment nor by the time × treatment interaction. However, a quadratic effect of time was observed. An interaction time × treatment was observed on MP, but possible differences within each week were not detected. Treatments also did not affect reproductive efficiency parameters. On average, the number of days to first detected postpartum estrus was 69.5, with 2.23 services per conception and 172.6 days open. The mean concentration of nonesterified fatty acids was 376.6 mmol L -1 and no effect of the interaction time × treatment, or of treatment, was observed. However, a linear effect was observed with time, with a decrease of 48.2 mmol L -1 per week. Key words: propylene glycol, calcium propionate, dairy power drench, Holstein cow, reproductive efficiency PRODUTOS GLICONEOGÊNICOS NÃO AFETAM RESPOSTAS PRODUTIVAS, REPRODUTIVAS E SANGÜÍNEA DE VACAS HOLANDESAS EM TRANSIÇÃORESUMO: O uso de produtos gliconeogênicos para vacas leiteiras no período de transição tem gerado respostas contraditórias na literatura, dificultando a sua recomendação. O objetivo deste experimento foi avaliar a suplementação de propileno glicol (PG), propionato de cálcio (PC) e "Dairy Power Drench ® " (DR) no período de transição de vacas leiteiras sobre a variação do escore da condição corporal (ECC), peso vivo (PV), produção de leite (PL), eficiência reprodutiva e concentração plasmática dos ácidos graxos livres (AGL). Foram utilizadas 165 fêmeas de dois rebanhos comerciais. Os tratamentos foram: C-Controle; DR-3 aplicações de "Dairy Power Drench ® " no pós-parto; PC-500 g diários de PC e PG-500 mL diários de PG, até o 50º dia pós-parto, em média. As causas de variação estudadas foram efeito de tratamento e efeito dos blocos formados em função da fazenda e do número de partos. Não foi observado efeito de interação de tempo (semanas) × tratamento ou de tratamento sobre ECC. Entretanto, houve efeito quadrático de tempo. ...

show abstract

“…It is most frequently hypocalcaemia in the first days after parturition that leads to the downer cow syndrome. Sometimes hypocalcaemia may be accompanied by hypophosphoraemia (Goff et al 1996) or irregularly increased magnesaemia (DoleÏel et al 1991; Kudláã et al 1995). Different prepartal measures are recommended to reduce the undesirable incidence of postpartal hypocalcaemia: a decrease in the Ca intake to less than 0.5% of dry matter…”

Section: Introductionmentioning

confidence: 99%

Dynamics of Calcaemia, Phosphoraemia and Magnesaemia at Different Prepartal Intakes of Calcium in Dairy Cows

Zelený¹,

Zelený²,

Kroupová

et al. 2007

Acta Vet. Brno

View full text Add to dashboard Cite

Zelen˘ T., J. Zelen˘, V. Kroupová P. Slavík: Dynamics of Calcaemia, Phosphoraemia and Magnesaemia at Different Prepartal Intakes of Calcium in Dairy Cows. Acta Vet Brno 2007, 76: 187-193.The objective of this study was to compare the efficiency of high and low Ca intake in cows with analytically defined levels of calcaemia, phosphoraemia and magnesaemia in the prepartal period, on their postpartal changes important for the diagnosis of postpartal diseases.In dairy cows (Czech Pied cattle) receiving a winter feed ration, the prepartal intake of Ca was adjusted from day 241 of pregnancy to 80% in group A (n = 15) and to 160% of the standard in group B (n = 9). In both groups the concentrations of Ca, P and Mg in blood serum were measured at the beginning of experimental diets, on day 12 before the expected parturition, and on days 1, 2, 3 and 4 after parturition.At the beginning of the experiment (42 days before parturition) the value of calcaemia was 1.82 ± 0.10 mmol·l -1 , phosphoraemia 1.61 ± 0.37 mmol·l -1 and magnesaemia 0.74 ± 0.6 mmol·l -1 of blood serum. After the 30-day feeding of experimental diet (day 12 before the expected parturition) higher hypocalcaemia was recorded in group A persisting to day 3 post partum. Phosphoraemia and magnesaemia were at the lower limit of reference values only from day 12 before the expected parturition to day 4 post partum. In group A three cows became recumbent until day 3 post partum with a decrease in magnesaemia below 0.5 mmol·l -1 .Phosphoraemia and magnesaemia were at the lower limit of reference values only from day 12 before the expected parturition to day 4 post partum. In group A three cows became downed until day 3 post partum with a decrease in magnesaemia below 0.5 mmol·l -1 .In group B with 160% intake of Ca, 12 days before the expected parturition calcaemia amounted to 2.20 ± 0.27 mmol·l -1 and hypocalcaemia ranging from 1.60 ± 0.45 to 1.80 ± 0.26 mmol·l -1 of blood serum persisted from day 1 to day 4 post partum. The average level of phosphoraemia in group B was maintained above 1.80 mmol·l -1 and magnesaemia was within the range of 0.93 -1.21 mmol·l -1 of blood serum.The results of the nutrition experiment document that for the prepartal adjustment of Ca intake aimed at a reduction in the incidence of the postpartal downer cow syndrome, it is necessary to determine calcaemia, phosphoraemia and magnesaemia in late-pregnant cows. In hypocalcaemia, hypophosphoraemia and especially hypomagnesaemia the prepartal diet with 80% coverage of Ca need leads to a higher risk of the downer cow syndrome accompanied by higher hypomagnesaemia.Nutrition, blood serum, Ca, P, Mg, hypocalcaemia, downer cow syndrome Disorders of Ca, P and Mg metabolism are still a health risk in dairy cows in spite of various dietetic preventive measures taken mainly in the prepartal period. It is most frequently hypocalcaemia in the first days after parturition that leads to the downer cow syndrome. Sometimes hypocalcaemia may be accompanied by hypophosphoraemia (Goff et al. 1996...

show abstract

Field Trials of an Oral Calcium Propionate Paste as an Aid to Prevent Milk Fever in Periparturient Dairy Cows

Cited by 84 publications

References 15 publications

Supplementing transition cows with calcium propionate-propylene glycol drenching or organic trace minerals: implications on reproductive and lactation performances

Supplementing transition cows with calcium propionate-propylene glycol drenching or organic trace minerals: implications on reproductive and lactation performances

Gluconeogenic supplements do not affect production, reproductive traits and blood metabolite of holstein cows during the transition period

Dynamics of Calcaemia, Phosphoraemia and Magnesaemia at Different Prepartal Intakes of Calcium in Dairy Cows

Contact Info

Product

Resources

About