2021
DOI: 10.1007/s10570-021-04319-2
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Filter made of cuprammonium regenerated cellulose for virus removal: a mini-review

Abstract: In 1989, Asahi Kasei commercialized a porous hollow fiber membrane filter (Planova™) made of cuprammonium regenerated cellulose, making it possible for the first time in the world to “remove viruses from protein solutions by membrane filtration”. Planova has demonstrated its usefulness in separating proteins and viruses. Filters that remove viruses from protein solutions, i.e., virus removal filters (VFs), have become one of the critical modern technologies to assure viral safety of biological products. It has… Show more

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Cited by 11 publications
(4 citation statements)
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“…152 With respect to cellulose derivatives used for water filtration, cellulose acetate and other derivatives are important materials. Indeed, there have even been some commercial regenerated cellulose-based products for extraction of viruses, such as Planova by Asahi Kasei, 153 and a wide range of cellulose esters made by Eastman. 154 A full description of these technologies is however beyond the scope of this article because we mostly deal with nanocellulose.…”
Section: Cellulose Used In Water Filtrationmentioning
confidence: 99%
“…152 With respect to cellulose derivatives used for water filtration, cellulose acetate and other derivatives are important materials. Indeed, there have even been some commercial regenerated cellulose-based products for extraction of viruses, such as Planova by Asahi Kasei, 153 and a wide range of cellulose esters made by Eastman. 154 A full description of these technologies is however beyond the scope of this article because we mostly deal with nanocellulose.…”
Section: Cellulose Used In Water Filtrationmentioning
confidence: 99%
“…Furthermore, inactivation efficacy is also affected by the physiochemical properties of the virus, such as the presence or absence of a viral envelope. Virus removal can be achieved through filtration using a virus removal filter to effectively remove viruses via size exclusion 10–14 . Virus filtration (VF) is superior to inactivation as it can remove a wide range of viruses regardless of their physiochemical properties.…”
Section: Introductionmentioning
confidence: 99%
“…Virus removal can be achieved through filtration using a virus removal filter to effectively remove viruses via size exclusion. [10][11][12][13][14] Virus filtration (VF) is superior to inactivation as it can remove a wide range of viruses regardless of their physiochemical properties. Moreover, VF does not apply undue stress to proteins.…”
mentioning
confidence: 99%
“…It is well-known that the membrane separation technology has been focused in various fields, such as biomedical [1] , petrochemical industry [2] , and environmental protection [3] etc. Among the many kinds of membrane forms, polymer hollow fiber membranes are regarded as the most popular part in the membrane application process due to simple operation, easily assemble, and small foot space and so on [4][5][6] . However, the hollow fiber membranes by wet-spinning method usually occurred breaking, flattening and peeling in filtration process owing to hydraulic flushing and membrane shaking [7][8] .…”
Section: Introductionmentioning
confidence: 99%