Final anatomic and visual outcomes appear independent of duration of silicone oil intraocular tamponade in complex retinal detachment surgery

Rhatigan, Maedbh; McElnea, Elizabeth; Murtagh, Patrick; Stephenson, Kirk; Harris, Elaine C.; Connell, Paul; Keegan, David

doi:10.18240/ijo.2018.01.15

Cited by 13 publications

(6 citation statements)

References 29 publications

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“…According to our data, the duration of SO endotamponade did not impact the visual outcome. Previous studies have reported similar results [ 4 , 22 ]. However, our cohort had a relatively homogeneous time frame, in which the SO remained in the patients’ vitreous cavities, ranging from six to fifteen weeks, which limits the significance of these results.…”

Section: Discussionsupporting

confidence: 84%

Impact of Silicone Oil Removal on Macular Perfusion

et al. 2022

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(1) Background: Silicone oil (SO) can be used as an endotamponade during vitreoretinal surgery for retinal detachment. There is emerging evidence that SO filling of the vitreous cavity and its removal may impact macular perfusion. So far, studies have not focused on choroidal sublayer perfusion, yet. (2) Methods: Optical coherence tomography angiography was applied in 19 patients with SO endotamponade before and four weeks after removal of SO. (3) Results: Perfusion of choriocapillaris increased significantly after SO removal, while perfusion of Haller’s and Sattler’s layer decreased significantly. (4) Conclusions: Removal of SO impacts choroidal perfusion and leads to a perfusion shift within choroidal sublayers. This study underlines that it is worth to conduct larger prospective studies that evaluate the choroidal perfusion and its functional implications in more detail.

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Section: Discussionsupporting

confidence: 84%

Impact of Silicone Oil Removal on Macular Perfusion

et al. 2022

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“…One of the major reasons for the absence of definitive agreement is the lack of knowledge about in vivo emulsification process of SO intraocularly and its variations among patients (Ni et al 2019). In fact, some clinicians have shown that prolonged SO tamponade does not increase those risks significantly (Pavlovic et al 1995;Lam et al 2008;Rhatigan et al 2018).…”

Section: Introductionmentioning

confidence: 99%

Complications associated with the use of silicone oil in vitreoretinal surgery: A systemic review and meta‐analysis

Valentín-Bravo

García-Onrubia

Andrés-Iglesias

et al. 2021

Acta Ophthalmologica

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Silicone oil (SO) still represents the main choice for long‐term intraocular tamponade in complicated vitreoretinal surgery. This review compared the complications associated with the use of SO and other vitreous substitutes after pars plana vitrectomy in patients with different underlying diseases. Meta‐analysis was conducted in accordance with PRISMA guidelines. We retrieved randomized clinical trials (RCTs), retrospective case–control and cohort studies evaluating the risk of using SO, published between 1994 and 2020, conducting a computer‐based search of the following databases: PubMed, Web of Science, Scopus and Embase. Primary outcome was the rate of complications such as intraocular hypertension, retinal re‐detachment, unexpected vision loss or hypotony. Secondary outcome was to compare the rate of adverse events of different SO viscosities, especially emulsification. Forty‐three articles were included. There were significant differences in intraocular hypertension (p = 0.0002, OR = 1.66; 95% CI = 1.27–2.18) and the rate of retinal re‐detachment (p < 0.0009, OR = 0.65; 95% CI = 0.50–0.64) between SO and other agents, including placebo. However, there were no differences in other complication rates. Silicone oil (SO)‐emulsification rate was non‐significantly higher in low than high SO viscosity, and results from other complications were comparable in both groups. The high quality of most of the studies included in this study is noteworthy, which provides some certainty to the conclusions. Among them is the high variability of the SO residence time. The fact that ocular hypertension and not hypotension is related to SO use. A clear relationship is not found for the so‐called unexplained vision loss, which affects a significant percentage of eyes. Re‐detachment cases are less if SO is used and that surprisingly there does not seem to be a relationship in the percentage of emulsification between the low‐ and high‐viscosity silicones. All these data warrant more standardized prospective studies.

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“…Silicone oil (SO) is a safe and well-tolerated intraocular tamponade agent widely used for the treatment of complicated vitreoretinal diseases such as inferior rhegmatogenous retinal detachments (RRDs), proliferative vitreoretinopathy (PVR), giant retinal tears, traumatic retinal detachments, and some cases of tractional retinal detachments 1 . As SO is less dense than water, SO has positive buoyancy and floats, and the contact angle is smaller than that of gas to the retina 2 .…”

Section: Introductionmentioning

confidence: 99%

Application of moving particle semi-implicit (MPS) method on retro-oil fluid using three-dimensional vitreous cavity models from magnetic resonance imaging

Gozawa

Watanabe²,

Iwasaki

et al. 2022

Sci Rep

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Silicone oil (SO) is a safe and widely used intraocular tamponade agent for treating complicated vitreoretinal diseases, such as retinal detachments (RRDs) with inferior proliferative vitreoretinopathy (PVR). However, as the human vitreous cavity is irregularly shaped, it is difficult to predict the area of the inferior retina covered with SO and the retro-oil fluid currents in each patient. Here, we performed fluid simulation analysis using the moving particle semi-implicit method on the oil cover rates and absolute velocity gradient of retro-oil fluid to the retina using vitreous cavity models derived from magnetic resonance imaging of patients to determine the appropriate amount of SO and postoperative position to achieve a sufficient tamponade effect on the inferior retina. In all seven vitreous cavity models tested, the inferior quadrant of the retina was completely covered by SO in more positions and the absolute velocity gradient of the retro-oil fluid in contact with the retinal wall caused by eye and head movements was lower when the vitreous cavity was filled with 95% SO and 5% retro-oil fluid versus 80% SO and 20% retro-oil fluid. Taken together, these findings have clinical implications for the treatment of complicated RRDs with inferior PVR requiring SO tamponade.

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Final anatomic and visual outcomes appear independent of duration of silicone oil intraocular tamponade in complex retinal detachment surgery

Abstract: Anatomic and visual outcomes in this cohort are in keeping with those reported in the literature. Favorable outcomes were seen with oil removal but duration of oil tamponade does not affect final attachment rate with modern surgical techniques and should be managed on a case by case basis.

Cited by 13 publications

References 29 publications

Impact of Silicone Oil Removal on Macular Perfusion

Impact of Silicone Oil Removal on Macular Perfusion

Complications associated with the use of silicone oil in vitreoretinal surgery: A systemic review and meta‐analysis

Application of moving particle semi-implicit (MPS) method on retro-oil fluid using three-dimensional vitreous cavity models from magnetic resonance imaging

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