“…The overall proportion of patients who were abstinent at M12, 35.9% in the ITT analysis and 54% in the per protocol analysis, is similar to that reported previously in series of patients with cancer (Ostroff et al, 1995;Potash, Karnell, Christensen, Vander Weg, & Funk, 2010) but is higher than that usually observed in series of patients without cancer (Nalpas et al, 2003). This suggests that the occurrence of a severe alcohol-/tobacco-related disease has a positive motivational impact on the decision to stop and also that the existence of a life-threatening disease does not suppress the desire to change (Christensen et al, 1999).…”