Fine needle aspiration biopsy in the oral cavity and head and neck region

Abstract

Abstract:The objective of the current study was to evaluate the sensitivity, specificity and accuracy of fine needle aspiration biopsy (FNAB) of submucous nodules from the oral cavity and head and neck region as an auxiliary diagnostic tool. Fifty patients with nodule lesions in the oral cavity and the head and neck region were selected. All of them were submitted to FNAB and to either incisional or excisional biopsy. The diagnoses from the FNABs were compared with the biopsy diagnosis as the gold standard. All the cases of FNAB were analyzed by a single oral pathologist prior to the biopsy diagnosis. The results showed that the sensitivity of FNAB was 75%, its specificity was 96% and its accuracy was 58.8%. The false positive and false negative rates were 6.7% and 13.3%, respectively. The positive predictive value was 86% and the negative predictive value was 93%. The inconclusive rate was 16/50. FNAB displayed a high success rate for identifying both malignant and benign lesions, but a low accuracy for making a final diagnosis.

Evaluation of the cell block technique as an auxiliary method of diagnosing jawbone lesions

“…3,7 However, the use of this technique for jaw lesions is not unanimously accepted. 2,3,[7][8][9] In this study, the biopsies were performed with thickergauge needles, followed by the processing of the aspirated material by the cell block technique, with the goal of decreasing cell dispersion and providing a larger amount of material for analysis.…”

Diagnostic accuracy and pitfalls of fine needle aspiration cytology and scrape cytology in oral cavity lesions

“…FNAC helps in avoiding surgical procedure in condition like non-neoplastic or inflammatory lesions and in metastatic tumors [5]. The most commonly described advantages of the oral FNAC are follow-up of previously diagnosed cases and preoperative diagnoses of lesions, allowing the surgeon and the patient to discuss and plan better for further course of action [6]. Scrape cytology has a wide clinical application in assessment of oral and oropharyngeal mucosal abnormalities, which include leukoplakia, erythroplakia and ulcers.…”

Intraoral and Oropharyngeal Lesions: Role of Fine Needle Aspiration Cytology in the Diagnosis

“…The estimation of the sensitivity, specificity and accuracy of the FNAC method was conducted according to the definitions of Trott, where sensitivity is the ability of the test to identify malignant lesions and specificity is the ability to identify benign lesions. Accuracy was calculated as the number of FNAC results that were similar to those of the regular biopsy [10].…”

“…These lesions have been traditionally treated on clinical basis and evaluated by surgical biopsy. Studies of transmucosal needle aspiration of oral cavity lesions are limited [1][2][3][4][5][6][7][8][9][10]. The oral cavity and oropharynx are readily accessible to fine needle aspiration (FNA) and it may be a useful technique for preliminary assessment.…”