Fine-needle aspiration biopsy of mediastinal masses: evaluation of 136 experiences

Abstract

Experience with 1 36 fine-needle aspiration biopsies of mediastinal masses performed in 84 patients is reviewed. Biopsies were performed in all compartments of the mediastinum regardless of age. The biopsy technique included a 22-gauge needle with limitation of needle passes to an arbitrary number of three. The biopsy procedure was guided by either fluoroscopy or computed tomography (CT); guidance by CT is advantageous in the region of the thoracic inlet, hilum, and middle mediastinum, ADLER ET AL.

Accuracy and sensitivity of computed tomography‐guided percutaneous needle biopsy of pulmonary hilar lymph nodes

“…The 93% accuracy rate with percutaneous hilar biopsies seen in this study is comparable to the accuracy rates reported with a combination of endobronchial ultrasound-and EUS-guided FNAB 14 and is at the upper end of the range for the accuracy rates reported for image-guided mediastinal biopsies (78%-94%) [8][9][10][11][12][13] and lung biopsies (88%-95%). [3][4][5][6][7]24,25 The diagnostic yield of endobronchial ultrasound may be increased by electromagnetic navigation techniques that allow biopsy of endobronchially invisible pulmonary lesions.…”

“…1 Currently, the most important prognostic factor for localized lung cancer is metastatic involvement of the mediastinal and hilar lymph nodes. 2 Transthoracic percutaneous needle biopsy (PNB) is routinely used to diagnose parenchymal [3][4][5][6][7] and accessible mediastinal [8][9][10][11][12][13] neoplasms.…”

“…[16][17][18][19] Previous studies evaluating the use of image-guided transthoracic PNB in the diagnosis of mediastinal adenopathy or central lung masses have not adequately evaluated PNB as a distinct technique, and the results are commonly reported with those of percutaneous mediastinal biopsy. 8,11,20 In this era of endobronchial ultrasound-and EUS-guided FNAB, 21,22 which have sensitivity and accuracy >92% for hilar biopsy, it is critical to understand the sensitivity, accuracy, and complication rates of image-guided hilar PNB. Therefore, we sought to evaluate the sensitivity and accuracy rates and complications associated with CT-guided PNB in the diagnosis of pulmonary hilar lesions.…”

CT-guided cutting-needle biopsies of selected chest lesions

“…These biopsies were pre- [9,[13][14][15][16][17][18].In an attempt to improve these previous results, we reintroduced the large cutting needle for the biopsy of carefully selected chest lesions. This report reviews our experience with 56 chest biopsies performed with a lange-bore cutting needle during the last 6 years.…”

“…The experience with the smaller gauge needles has been favorable in the evaluation of nonlymphoprolifenative malignancies, with high diagnostic yields and low complication rates [7-1 2]. Material provided by aspiration biopsy has been less useful in the evaluation of lymphoma, thymoma, and benign disorders, all of which often require histology for a specific diagnosis [9,[13][14][15][16][17][18].…”