Fine-Needle Aspiration Cytological Diagnosis of Neck Masses

Ashraf, Mohammad Javad; Raad, Hanieh; Azarpira, Negar; Khademi, Bijan; Shishegar, Mahmood; Gandomi, Behrooz; Hagpanah, Sezaneh; Adibi, P

doi:10.1159/000371412

Cited by 9 publications

(8 citation statements)

References 16 publications

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“…It provides valuable information about the tumour regarding its origin (salivary/non‐salivary), nature of the lesion (benign/malignant) and grade of the tumour (low grade/high grade). The cumulative information obtained guides the surgeon in deciding the surgical plan and in prognosticating the patient regarding the probable outcome and need for adjuvant therapy …”

Section: Introductionmentioning

confidence: 99%

Incorporation of the Milan system in reporting salivary gland fine needle aspiration cytology—An insight into its value addition to the conventional system

Kaushik

Bhatia

Sarin

et al. 2019

Diagnostic Cytopathology

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Background: Milan System for Reporting Salivary Gland Cytology (MSRSGC) was introduced to standardise the terminology and reporting of salivary gland cytology.The purpose of our study was to compare the conventional system and the proposed Milan System to look for concordance rates in cytohistopathologic correlation and any value addition to the conventional system.Methods: This was a retrospective cross sectional observational study. The fine needle aspiration cytology (FNAC) were reported in the conventional manner and were correlated with the surgical specimen. The cyto-histopathological correlation was studied to look for concordance rates. FNAC were retrospectively reviewed and were categorised according to the Milan system. These reports were correlated with surgical specimen category wise and concordance rates, risk of neoplasm (RON), risk of malignancy (ROM) were calculated.Results: Salivary gland FNAC done during the study period was 323 in number and histopathological correlation was available for 153 cases. The concordance rate of type specific diagnosis was 80.3% as per conventional system. With the application of Milan system, the concordance rates rose to 88.07% with an improvement of 6.67%(excluding non-diagnostic). RON and ROM for non-diagnostic (I)-50%, 50%; non-neoplastic (II)-22%,0%; atypia of unknown significance (III)-66%, 11%; benign neoplasm (IVA)-98%, 3%; salivary gland neoplasm of uncertain malignant potential (IVB)-93%,14%; suspicious for malignancy (V)-100%, 60% and malignant (VI) was 100%, 94%.Conclusion: The broad categorisation provided by the Milan system represents the gross rate of malignancy and helps in deciding the management plan and eventual surgical plan. Thus, it adds value to conventional reporting of salivary gland cytology.K E Y W O R D S FNAC, Milan system, salivary gland cytology

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Section: Introductionmentioning

confidence: 99%

Incorporation of the Milan system in reporting salivary gland fine needle aspiration cytology—An insight into its value addition to the conventional system

Kaushik

Bhatia

Sarin

et al. 2019

Diagnostic Cytopathology

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“…FNAC is broadly adopted as a longstanding tool for the diagnosis and the planning of an effective treatment of head and neck masses . Nevertheless, its sensitivity and specificity reporting in the literature are widely variable and mainly depend on the site of the mass . Besides, some diagnoses remain cytologically challenging because of the rarity of some lesions as for salivary gland pathology.…”

Section: Introductionmentioning

confidence: 99%

Accuracy of fine‐needle aspiration cytology of head and neck masses

Rammeh

Romdhane

Sassi

et al. 2018

Diagnostic Cytopathology

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Background Head and neck masses are a common presentation in daily practice and can be challenging to both clinicians and cytopathologists. Fine needle aspiration cytology (FNAC) is a widely used method for the diagnosis of head and neck masses. The aim of the study was to assess our institutional experience of the accuracy of FNAC in the diagnosis of head and neck masses. Methods A total of 1262 FNACs were conducted from January 2013 to December 2016 and subdivided into benign and malignant categories. The thyroid and salivary glands FNACs were classified according to the Bethesda System for Reporting Thyroid cytopathology and to the Milan System for Reporting Salivary Gland Cytopathology respectively. The measures of diagnostic accuracy of FNAC were determined taking histology as a gold standard. Results A total of 7 false negative (FN) and 6 false positive (FP) FNACs were identified. Overall sensitivity and specificity of FNAC for a malignant diagnosis were 92% and 94.4%, respectively. Accuracy of FNACs of head and neck masses was 93.5% for all sites. The salivary gland group had the highest rate of FN (2.8%). All FP were reported in the thyroid group. These cases were cytologically classified suspicious for malignancy (n = 3) and papillary carcinoma (n = 3) and proved to be lymphocytic thyroiditis on final histology. Among the most common locations, cytology of lymph nodes provided the best sensitivity (98.2%). Salivary glands as well as lymph nodes had the best specificity (100%). Conclusion FNAC of head and neck masses has a high accuracy allowing a correct therapeutic management. However, this accuracy depends on the anatomic location of the mass.

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“…[3,12] There are studies evaluating the efficacy of FNAC in head and neck masses in the literature. Ashraf et al [13] investigated the efficacy of FNAC in thyroid and non-salivary gland head and neck masses.…”

Section: Discussionmentioning

confidence: 99%

Fine needle aspiration cytology in the diagnosis of lymph nodes: Correlation with histopathological diagnosis

Altınboğa¹

2019

South Clin Ist Euras

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Lymph node fine-needle aspiration cytology (FNAC) is usually the first step in the evaluation of an enlarged lymph node. It is a rapid, minimally invasive, and less expensive procedure than histopathological examination. The aim of this study was to analyze the diagnostic adequacy of lymph node FNAC compared with histopathological diagnosis. Methods: A total of 171 lymph node FNAC results performed between 2016 and 2017 were reviewed for inclusion in this study. In all, the FNAC results of 41 cases sampled with Tru-Cut (Merit Medical Systems, Inc., South Jordan, UT, USA) and/or excisional biopsy were compared with the histopathological findings. Results: The FNAC diagnosis of 13 benign cases (13/13), 3 reported as atypia of undetermined significance (3/4), 8 that were suspected malignancy (8/9), and 13 malignant cases (13/13) were well correlated with the final histopathological diagnoses. The overall diagnostic sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were found to be 95.4%, 94.1%, 95.4%, 94.1%, and 94.9% respectively. The false negative rate was 2.4% and the false positive rate was 2.4%. Conclusion: FNAC of lymph nodes is a highly sensitive and specific method to diagnose lymph node pathologies. It is a reliable diagnostic tool in the evaluation of an enlarged lymph node.

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Fine-Needle Aspiration Cytological Diagnosis of Neck Masses

Cited by 9 publications

References 16 publications

Incorporation of the Milan system in reporting salivary gland fine needle aspiration cytology—An insight into its value addition to the conventional system

Incorporation of the Milan system in reporting salivary gland fine needle aspiration cytology—An insight into its value addition to the conventional system

Accuracy of fine‐needle aspiration cytology of head and neck masses

Fine needle aspiration cytology in the diagnosis of lymph nodes: Correlation with histopathological diagnosis

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