Fine Needle Aspiration Cytology in Lesions of the Nose, Nasal Cavity and Paranasal Sinuses

Gupta, Nalini; Kaur, Jasleen; Srinivasan, Radhika; Das, Ashim; Mohindra, Satyawati; Rajwanshi, Arvind; Nijhawan, Raje

doi:10.1159/000320907

Cited by 21 publications

(22 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Physalliferous cells are characteristic of chordoma, but may be few. Chordomas are decorated by cytokeratin, EMA and S-100 (13). In the present case thorough search neither revealed cells with prominent nucleoli nor with spidery cytoplasm.…”

Section: Case Reportcontrasting

confidence: 50%

See 1 more Smart Citation

Nasal polyp – an incidental paraganglioma

Srivastava¹,

Wadhwa²,

Gupta³

et al. 2013

TJPATH

View full text Add to dashboard Cite

The nose is an uncommon site for head and neck paraganglioma. The diagnosis is seldom established pre-operatively; its rarity, infrequent functionality and often benign biologic outcome underlie this fact. We present one such case in a 60-year-old man who presented with right nasal obstruction and episodic epistaxis. Rhinoscopy revealed a fleshy polypoid mass arising from the anterior cartilaginous nasal septum. Imaging studies excluded extra-nasal extension. The tumor was highly vascular showing numerous variable sized, mostly thin walled branching blood vessels akin to stag-horn shape simulating a vascular neoplasm. There were large areas of hyalinization. The typical tumor morphology was discernible only in focal areas. Immuno-histochemistry confirmed the diagnosis. The tumor cells expressed neuron specific enolase; S-100 stain demonstrated a vague zell-ballen pattern. Paraganglioma is a rare histologic diagnosis in nasal polypectomy specimen. We discuss the approach to exclude its morphologic mimics including vascular tumors.

show abstract

Section: Case Reportcontrasting

confidence: 50%

“…Cellular areas of PGs may resemble malignant melanoma, metastatic carcinoma, chordoma, perivascular epithelioid cell tumor (PEComa), glomus tumor and EH, all tumors rare to the nose (11)(12)(13)(14)(15)(16)(17). They share cytologic feature of voluminous clear to eosinophilic cytoplasm of the tumor cells.…”

Section: Case Reportmentioning

confidence: 99%

Nasal polyp – an incidental paraganglioma

Srivastava¹,

Wadhwa²,

Gupta³

et al. 2013

TJPATH

View full text Add to dashboard Cite

show abstract

“…We consistently tried to perform FNAC to get an idea regarding the pathological nature of the lesion, and though FNAC has often been rendered only as a corroborative evidence prior to surgery secondary to imaging [6,13], even being considered non-diagnostic in few instances [14,15], in our caseseries, this was not always true. In fact, in some of the recent studies, the role of FNAC as an important tool in the diagnostic work-up in various epidermal lesions has been underlined and well-explored, like in nose and paranasal sinus masses that included epidermal inclusion cysts [16], in pediatric neck masses like dermoids, sebaceous cysts etc. [17], and in specific skin adnexal lesions like pilomatrixoma [17,18].…”

Section: Discussionmentioning

confidence: 99%

Epidermoid Cysts in Head and Neck: Our Experiences, with Review of Literature

Dutta

Saha

Biswas

et al. 2011

Indian J Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

Epidermoid cysts are benign lesions, characterized by cystic spaces lined by simple squamous epithelium (epidermoid cyst), containing skin adnexa (''true'' dermoid cyst) or tissues of all three germ layers (teratoid cyst). Head and neck constitute *7% of all cases of epidermoid and dermoid cysts. There is often a diagnostic dilemma with the more common cystic lesions of this region. A retrospective case-series study of histologically proved epidermoid cysts in the head-neck region, from February 2008 to January 2011, in the Department of Otorhinolaryngology and Head-Neck Surgery of a tertiary Government teaching hospital in eastern India. The diagnosis was reached by fine needle aspiration cytology FNAC and subsequent histopathology where feasible. Necessary imaging was done for evaluation and management. A total of 28 cases were analyzed. 5 were female, with a male: female ratio of 4.6. Age range was from 2 to 60 years (mean = 30). Excision was the preferred treatment in 20 cases (71.4%). Various sites like the submandibular region (5), pinna (5), sublingual region (1), periorbital (6), suprasternal (6), along the anterior border of sternocleidomastoid (1) and glabella (3) were involved, along with an iatrogenic implantation epidermoid cyst in a tracheostomy scar. Some of the interesting cases presenting with clinical dilemma have been emphasized. Epidermoid cysts are relatively less common in the head-neck region, hence are liable to be misdiagnosed. In this case-series, few cases presenting with enough elements of confusion and dilemma are discussed with overall analysis and review of the related literature.

show abstract

“…[5] Fine needle aspiration of paranasal sinus lesions is difficult due to closed architecture, and only one study has been documented in the literature. [6] Intraoperative cytology and frozen section examinations of lesions of nose and paranasal sinuses are useful, quick, and reliable diagnostic technique for rapid and early diagnosis in the operation theatre and can be used as an adjunct to histopathology for better management of patients. [7] The presenting features, symptomatology and advanced imaging technique help to reach a presumptive diagnosis but histopathological examination remains the mainstay of final definitive diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Clinicopathological study of Sinonasal Masses

Mane

Agale

2017

APALM

View full text Add to dashboard Cite

Background: Sinonasal mass is a common finding in the Otorhinolaryngology Department. These can be non-neoplastic or neoplastic. Nasal obstruction is the most common clinical presentation. Imaging studies are not always conclusive in these cases. So, the present study aimed at clinical presentation and histopathological classification of sinonasal masses.for histopathological examination and were stained by Hematoxylin and Eosin stain. Special stains were used wherever required. Immunohistochemistry was carried on cases with diagnostic difficulties. malignant tumours. Non-neoplastic lesions and benign tumours were commonly seen in middle age group while malignant tumours were seen in adult patients. Males were predominantly affected in non-neoplastic lesions and benign tumours. Malignant tumours showed female dominance. Nasal obstruction was the most common complaint. Overall, inflammatory nasal polyps were most common lesions. Inverted papillomas were most common benign tumours. Sinonasal undifferentiated carcinomas accounted for majority of malignant tumours. Conclusion:Sino-nasal masses or polyps can be non-neoplastic or neoplastic lesions and histopathological examination remains the mainstay in differentiating these lesions.

show abstract

Fine Needle Aspiration Cytology in Lesions of the Nose, Nasal Cavity and Paranasal Sinuses

Cited by 21 publications

References 37 publications

Nasal polyp – an incidental paraganglioma

Nasal polyp – an incidental paraganglioma

Epidermoid Cysts in Head and Neck: Our Experiences, with Review of Literature

Clinicopathological study of Sinonasal Masses

Contact Info

Product

Resources

About