Fine-needle aspiration cytology of metastatic squamous-cell carcinoma arising in a pilonidal sinus, with literature review

Pilonidal Disease- Review Article

“…Continuity with a cyst is usually easily demonstrated. [93] • The tumour grows locally before metastasizing to inguinal lymph nodes. [90] • Successful treatment with wide excision alone (philipshen et al, 1981) or in combination with Adjuvant chemotherapy (lerner and deitrick, 1979) has been reported.…”

Treatment of Malignancy Arising in Pilonidal Disease

“…6,13 The first case was reported by Wolff in 1900 14 and an additional 58 such cases have been reported in the world literature, including our own three cases. [2][3][4][5][6][7][8][9][10][11][12]15 Diagnosis may be made on clinical examination and biopsy of a chronic ulcer with friable and necrotic margins, or it may occur on an incidental finding on histological examination of excised pilonidal sinus. Lesions are usually large tumors and frequently more than 5 cm in diameter.…”

“…4 Rarely, the diagnosis is established after fine-needle aspiration of a metastatic inguinal lymph node. 8 Endoscopy may be necessary to rule out extension in the rectum. Computerized tomography or magnetic resonance imaging is indicated to demonstrate local extent and to detect intra-abdominal metastases, including the spread to iliac and para-aortic lymph nodes, and to complement physical examination of the inguinal lymph nodes.…”

“…After an extensive literature survey, an additional 12 cases could be added. [3][4][5][6][7][8][9][10][11][12] …”

“…Until now, only 56 such cases have been reported in the international literature. [2][3][4][5][6][7][8][9][10][11][12] Herein, we report three new cases treated in the Departments of Surgical Oncology and Radiotherapy at the University Hospital in Herakleion, Greece, and at The Netherlands Cancer Institute in Amsterdam during the last 5 years. In a collective review, the data of these 59 cases were analyzed, especially regarding treatment and outcome, to form treatment recommendations with the aim of reducing the recurrence rate and improving survival.…”