Fine Needle Aspiration Cytology versus Histopathological Examination in Head and Neck Lesions

Saraf, Anju; Gupta, Sachin; Manhas, Amit; Kalsotra, Parmod; Goswami, K. C.

doi:10.9790/0853-151003122128

Cited by 3 publications

(4 citation statements)

References 14 publications

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“… 15 FNAC has been reported to be more accurate in diagnosing some lesions like salivary gland and lymph node lesions while diagnosing some others with less accuracy. 9 15 16 …”

Section: Discussionmentioning

confidence: 99%

“…This is similar to the findings of Saraf et al ., where a low sensitivity of FNAC was reported for malignancy with no false positive although in this study a false positive rate of 4.6% was found. 16 Balakrishnan et al . in another study also concluded that FNAC failed to reliably distinguish benign from malignant salivary gland tumours.…”

Section: Discussionmentioning

confidence: 99%

“…This study shows that FNAC have a higher specificity than sensitivity in the diagnosis of malignant lesions of head and neck region and this agrees with findings in other studies. 16 20 The possible reasons sighted for inability of FNAC to correctly diagnose malignant lesions include sampling error, harvesting of inflammatory cells or necrotic tissue. 16 21 22 The procedure for obtaining these FNAC specimen, its preparation and interpretation may also affect the ultimate result.…”

Section: Discussionmentioning

confidence: 99%

“… 16 20 The possible reasons sighted for inability of FNAC to correctly diagnose malignant lesions include sampling error, harvesting of inflammatory cells or necrotic tissue. 16 21 22 The procedure for obtaining these FNAC specimen, its preparation and interpretation may also affect the ultimate result. Although, the anatomical pathologists in conjunction with anatomical pathology laboratory technicians are involved in all these steps in our tertiary health center, however, there are different cadres of anatomical pathologists and anatomical pathology laboratory technicians with different levels of experience and expertise that are involved in this diagnostic process; all these influence the ultimate cytopathologic results obtained.…”

Section: Discussionmentioning

confidence: 99%

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Diagnostic accuracy of fine-needle aspiration cytology in head and neck lesions from a tertiary health facility in Southwestern Nigeria

et al. 2020

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Background: Fine-needle aspiration cytology (FNAC) is widely employed as an initial investigative tool in the diagnosis of various lesions in the body, however, it is limited in the provision of precise architectural detail of lesions. This is said to be responsible for the wide variation in the documented usefulness and accuracy relative to histopathology. This study aimed to correlate cytopathological and histopathological examination (HPE) of head and neck lesions, and assess the usefulness and accuracy of FNAC in our center. Materials and Methods: This was a retrospective study that utilized historical data obtained from case notes and histopathology records of 91 patients that had both FNAC and HPE done for head and neck lesions in our center during the study. The FNAC results were correlated with that of the histopathological diagnosis to obtain the accuracy of the FNAC diagnosis. Diagnostic validity of FNAC in terms of sensitivity, specificity, and predictive value were also evaluated. Results: A total of 91 FNAC-HPE sample pairs were included. The Sensitivity and specificity for benign lesion was 95.4% and 42.3%, respectively, while for sensitivity and specificity for malignant lesion was 31.8% and 96.9%, respectively. The overall Sensitivity and specificity for cytology was 96.8% and 30.4%, respectively. Conclusion: FNAC appears to be a useful tool in the initial assessment of head and neck lesions in our center, however, the high rate of missed diagnosis especially as concerned malignancies has dire negative treatment implications. There is need to develop capacity for improved skill in making cytopathologic diagnoses among anatomical pathologists involved in the use of FNAC as diagnostic and screening tool.

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“… 15 FNAC has been reported to be more accurate in diagnosing some lesions like salivary gland and lymph node lesions while diagnosing some others with less accuracy. 9 15 16 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Diagnostic accuracy of fine-needle aspiration cytology in head and neck lesions from a tertiary health facility in Southwestern Nigeria

et al. 2020

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Diagnostic Efficacy of Fine Needle Aspiration Cytology in Neck Swelling - A Systematic Review

Niveditha¹,

Chandak²,

Lamture³

2021

jemds

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BACKGROUND Neck swellings are one of the most common presenting complaints of patients in all age groups. Aetiology of neck swelling has various causes congenital or acquired, cystic, inflammatory or neoplastic and vascular. Our aim was to study the diagnostic efficacy of fine needle aspiration cytology (FNAC) in neck swellings. METHODS A systematic search on the database of PubMed, Google Scholar and Academia for studies on diagnosing neck swellings by FNAC where histopathological diagnosis is considered gold standard was done and reviewed. The keywords used for searching were FNAC, neck swellings, diagnostic efficacy of FNAC. RESULTS Fine needle aspiration cytological study was considered as the first line investigation for patients presenting with neck swellings and its sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy has been reported. CONCLUSIONS FNAC is easy to perform with almost nil complications and excludes the need for a biopsy which is more complex with complications like infection and haemorrhage. FNAC in neck swellings should be considered as a complementary investigation for histopathological studies, but never a substitute. KEY WORDS FNAC, Thyroid, Tuberculosis (TB) Lymphadenitis, Lymphoma, Secondaries in Neck

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Diagnostic Accuracy of Fnac in Cervical Lymphadenopathy

Vishwanath

Reddy

Madhuri

et al. 2023

ijsr

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Introduction:- To study the role of FNAC in diagnosing cervical lymphadenopathy as compared to open biopsy for histopathological examination. Material And Methods:- The present study is carried out at SVS Medical College And Hospital, Mahabubnagar, over a period of two years from November 2020 to March 2022. The study consists of 50 consecutive cases, diagnosis is based on pathological ndings. Inclusion Criteria - Patients more than 12 years of age and Patients presenting with cervical lymph node enlargement. Exclusion Criteria - Patients less than 12 years of age, All other neck swellings other than cervical lymphadenopathy. Patients where FNAC and/or Biopsy of the node could not be carried out were excluded. Results :- According to Age Distribution - Out of 50 cases, maximum number of cases were in the age group of 21-30 years, Next common in the age group of 12- 20 years, Thus the second and third decade constituting 30 of the 50 cases (60%), Lowest age recorded was 12 years of age and highest 82 years of age. According to Sex Distribution - Out of the 50 cases studied, 28 cases were males and 22 cases females, The male to female ratio was 1.27 : 0.78. According to Sensitivity and Specicity - accuracy of 98.50% for tuberculous lymphadenopathy to histological correlation. Conclusion:- Cervical lymphadenopathy is an important disease, commonly come across, and always calls for meticulous attention, analysis and treatment. FNAC being inexpensive, quick in getting the results and easy to perform as an out patient procedure under local anesthesia, is one of the important and essential diagnostic procedure. FNAC can be deemed as a frontline investigation. If it is diagnostic it can avoid unnecessary excision biopsy for the cases which can be managed conservatively

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Fine Needle Aspiration Cytology versus Histopathological Examination in Head and Neck Lesions

Cited by 3 publications

References 14 publications

Diagnostic accuracy of fine-needle aspiration cytology in head and neck lesions from a tertiary health facility in Southwestern Nigeria

Diagnostic accuracy of fine-needle aspiration cytology in head and neck lesions from a tertiary health facility in Southwestern Nigeria

Diagnostic Efficacy of Fine Needle Aspiration Cytology in Neck Swelling - A Systematic Review

Diagnostic Accuracy of Fnac in Cervical Lymphadenopathy

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