Fine needle cytology-diagnostic tool for palpable orbital and eyelid lesions

Rastogi, Nupur; Gupta, Anvita

doi:10.18203/2320-6012.ijrms20172453

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…Four of the sixteen cases in our study were diagnosed with DLBCL constituting the second most prevalent NHL type. This concurs with the survey of Roositalab and Rastogi et al 12 , 14 The other possibility when there are sheets of mature plasma cells with clonality being expressed on ICC suggests a solitary plasmacytoma in the absence of marrow involvement 15 . In our study, there was one case of solitary plasmacytoma.…”

Section: Discussionsupporting

confidence: 93%

The utility of fine needle aspiration cytology in orbital haematolymphoid neoplasms

et al. 2020

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Background Orbital hematolymphoid lesions are rare and usually encountered in elderly patients. Orbital lesions are not easy to biopsy: hence fine needle aspiration cytology (FNAC) can be a very good diagnostic modality for these lesions. Materials and Methods Cases of orbital masses subjected to FNAC dating from 2013 to 2020 were retrieved from our archives. A total of 16 cases with biopsy confirmation were included. All clinical details, the type of procedure, details of the immunocytochemistry (ICC) performed on smear, follow‐up biopsy, and their haematological work‐up were analysed in detail. Results Sixteen biopsy‐confirmed cases had been diagnosed as orbital haematolymphoid lesions on cytomorphology and further categorised with ancillary studies including ICC. In twelve instances, the cytology impression was congruent with the histopathological diagnosis and eight of the sixteen cases (50%) proved to be primary orbital lymphoma. Four were secondary orbital lymphomas and the remaining four included one case each of plasmacytoma, myeloid sarcoma, Rosai‐Dorfman disease and angiolymphoid hyperplasia with eosinophilia. Conclusion FNAC is a minimally invasive procedure for diagnosing most of the haematolymphoid orbital lesions and it has a rapid turnaround time. The accuracy of cytomorphology combined with ICC on smears/cell blocks can be as good as a biopsy for exact categorisation. Additionally, aspirate smears are preferred samples for cytogenetics compared to formalin‐fixed tissue blocks, as molecular cytogenetics techniques are frequently employed for diagnostic, prognostic, and therapeutic purposes.

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Section: Discussionsupporting

confidence: 93%

The utility of fine needle aspiration cytology in orbital haematolymphoid neoplasms

et al. 2020

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“…Cytomorphological spectrum of orbital and peri-orbital lesionsAnnals of Pathology and Laboratory Medicine, Vol. 11, Issue 4, April 2024 to the age range of 0-20 years, followed by 20-40 years group which was similar to the study by Rastogi N et al[18] …”

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confidence: 89%

Cytomorphological Spectrum of Orbital and Peri-orbital Lesions – A Retrospective Study from A Tertiary Care Center, Manipur, India

Singh,

Pukhrambam,

Shimray

et al. 2024

Ann of Pathol and Lab Med

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Background Fine needle aspiration cytology (FNAC) is a reliable, safe and simple diagnostic technique which is being implemented in diagnosing palpable and/or visible lesions in the body. This study was conducted for evaluating the role of FNAC as a routine screening/diagnostic tool in a spectrum of orbital and periorbital lesions. The aim of this study was to evaluate the role of FNAC in orbital and periorbital lesions. Methods A hospital based cross-sectional study was conducted in the Cytology section, Department of Pathology, RIMS for a period of 10 years from April 2013 to May 2022. A total of 95 cases with orbital and periorbital lesions were inducted in the study through purposive sampling. FNAC procedure was done using 10cc/20cc syringe with 23G/22G needle with or without a Cameco handle. Slides were stained using MGG (May-Grunwald Giemsa) and Pap (Papanicolaou) stains followed by their microscopic examination. Demographic parameters such as age and gender as well as clinical parameters such as size, site and duration of the lesion were analyzed. Result The mean age of patients was found to be 33 years with a slight male predominance (54 patients; 56.84%). The adequacy of FNAC was 96.82%. Epidermal Inclusion Cyst (30 cases; 31.58%) was the commonest lesion. Five cases (5; 5.26%) were malignant on cytopathology. By applying Kappa statistics, a near perfect agreement (k=0.86) between FNAC and histopathology was observed, being statistically significant, p=0.01 (<0.05). Conclusion: In our study, a high concordance/agreement was observed for the neoplastic lesions, thereby establishing FNAC as a useful tool for screening as well as diagnosing orbital and periorbital lesions. It surrogates other invasive procedures, eliminating complications in nonresectable or inapproachable lesions.

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Fine needle cytology-diagnostic tool for palpable orbital and eyelid lesions

Cited by 2 publications

References 9 publications

The utility of fine needle aspiration cytology in orbital haematolymphoid neoplasms

The utility of fine needle aspiration cytology in orbital haematolymphoid neoplasms

Cytomorphological Spectrum of Orbital and Peri-orbital Lesions – A Retrospective Study from A Tertiary Care Center, Manipur, India

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