Fine structure of a glomus tumor of the tongue and expression of C type virus in its tumor cells

Clinical Features of Multiple Glomus Tumors

“…Pleomorphic features and increased mitoses are usually absent. 29 However, rare cases with cellular atypia and mitosis have been reported [30][31][32] as have rare cases of metastases with malignant variants 33 Brathwaite and Poppiti 34 and Khoury and colleagues 35 found no evidence of necrosis, increased mitoses, or cytologic atypia in any of the lesions in our patient series.…”

Glomus Tumor of the Upper Lip.

“…Glomus tumor is a relatively rare neoplasm derived from the glomus body and typically occurs in the skin of the finger, especially beneath the fingernails and fingertips [1][2][3]. The tumor also occurs uncommonly in oral region, and a small number of cases in the hard palate [4,5], gingiva [6][7][8], cheek [9,10], tongue [11,12] and lip [13,14] have been reported (Table 1). Although glomus tumors usually occur as a single lesion, a few cases of multiple lesions have been described [2,15,16].…”

“…It has been reported that glomus tumor cells have the characteristics of smooth muscle cells, based on immunohistochemical [10,14,[17][18][19][20][21] and ultrastructural [10][11][12][13]17,18,20,[22][23][24][25] studies. Miettinen et al [17] and Googe et al [21] reported that glomus tumor cells were negative for desmin, as the same result in the glomus body.…”

“…Cutaneous and subcutaneous glomus tumors in various locations have been reported [2,3]. A small number of glomus tumors have also been described in oral locations such as the hard palate [4,5], gingiva [6][7][8], cheek [9,10], tongue [11,12] and lip [13,14].We report a case of glomus tumor occurring in the upper lip, in which the nature of the tumor cells was examined by immunohistochemistry.…”

Glomus Tumor of the Oral Cavity: Report of a Rare Case and Literature Review

“…However, GT is extremely rare in the mouth. To the best of our knowledge, there are only 23 well-documented cases of GT involving the mouth reported in the Englishlanguage literature (2,3,(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27). The aim of this report is to describe the histopathological and immunohistochemical features of a rare case of GT involving the upper lip, and to review the pertinent literature.…”