We describe the response of an insoluble surfactant monolayer spreading on the surface of a thin liquid film to small disturbances in the film thickness and surfactant concentration. The surface shear stress, which derives from variations in surfactant concentration at the air-liquid interface, rapidly drives liquid and surfactant from the source toward the distal region of higher surface tension. A previous linear stability analysis of a quasi-steady state solution describing the spreading of a finite strip of surfactant on a thin Newtonian film has predicted only stable modes. ͓Dynamics in Small Confining Systems III, Materials Research Society Symposium Proceedings, edited by J. M. Drake, J. Klafter, and E. R. Kopelman ͑Materials Research Society, Boston, 1996͒, Vol. 464, p. 237; Phys. Fluids A 9, 3645 ͑1997͒; O. K. Matar Ph.D. thesis, Princeton University, Princeton, NJ, 1998͔. A perturbation analysis of the transient behavior, however, has revealed the possibility of significant amplification of disturbances in the film thickness within an order one shear time after the onset of flow ͓Phys. Fluids A 10, 1234 ͑1998͒; ''Transient response of a surfactant monolayer spreading on a thin liquid film: Mechanism for amplification of disturbances,'' submitted to Phys. Fluids͔. In this paper we describe the linearized transient behavior and interpret which physical parameters most strongly affect the disturbance amplification ratio. We show how the disturbances localize behind the moving front and how the inclusion of van der Waals forces further enhances their growth and lifetime. We also present numerical solutions to the fully nonlinear 2D governing equations. As time evolves, the nonlinear system sustains disturbances of longer and longer wavelength, consistent with the quasi-steady state and transient linearized descriptions. In addition, for the parameter set investigated, disturbances consisting of several harmonics of a fundamental wavenumber do not couple significantly. The system eventually singles out the smallest wavenumber disturbance in the chosen set. The summary of results to date seems to suggest that the fingering process may be a transient response which nonetheless has a dramatic influence on the spreading process since the digitated structures redirect the flux of liquid and surfactant to produce nonuniform surface coverage. © 1999 American Institute of Physics. ͓S1054-1500͑99͒02001-7͔ Surfactant molecules play a vital role in many biological and industrial processes because of their native ability to lower surface tension in proportion to their concentration. Their presence greatly improves the wetting and spreading capability of commonplace substances like inks, paints, and herbicides. Lung surfactants produced in the alveoli are critical in maintaining lung compliance. A deficiency in lung surfactant production, for example, is known to cause pulmonary edema and other respiratory difficulties. When surfactant molecules contact a liquid surface of higher surface tension, a shear stress develops...