First case of Acanthamoeba keratitis in Malaysia

Kamel, A. G. M.; Ahmad, Norazah

doi:10.1016/0035-9203(95)90429-8

Cited by 23 publications

(11 citation statements)

References 2 publications

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“…It has been recognized in almost all parts of the world [8][9][10][11][12]. Evidence from most studies has suggested that soft contact lens wearers are at the greatest risk for AK; in a recent study, contact lens wear was reported in 80-86% of cases [13][14][15].…”

Section: Discussionmentioning

confidence: 96%

Perioperative treatment and prognostic factors for penetrating keratoplasty in Acanthamoeba keratitis unresponsive to medical treatment

Shi

Liu

Gao

et al. 2009

Graefes Arch Clin Exp Ophthalmol

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Section: Discussionmentioning

confidence: 96%

Perioperative treatment and prognostic factors for penetrating keratoplasty in Acanthamoeba keratitis unresponsive to medical treatment

Shi

Liu

Gao

et al. 2009

Graefes Arch Clin Exp Ophthalmol

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“…Kes ini melibatkan seorang wanita yang memakai kanta sentuh. Bilangan kes AK terus meningkat di Malaysia dan kebanyakannya melibatkan pengguna kanta sentuh (Kamel et al , 2003.…”

Section: Pendahuluanunclassified

Kerentanan Acanthamoeba spp. terhadap Larutan Disinfektan Pelbagai Guna Kanta Sentuh

Ghani¹,

Omar²,

Nordin³

et al. 2015

JSM

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“…Although keratitis due to Acanthamoeba sp. has been detected in many countries, few cases have reportedly been recognized in South-east Asia (Mohammed Kamel & Norazah 1995;Kosrirukvongs et al 1999). The purposes of this report are to describe the first two diagnosed cases of Acanthamoeba infection of the cornea in Thai patients after minor corneal trauma, and to characterize Acanthamoeba subpopulations in isolates from these patients by the mitochondrial DNA restriction fragment length polymorphism (mtDNA-RFLP) analysis compared with cyst morphology.…”

Section: Introductionmentioning

confidence: 99%

“…Although keratitis due to Acanthamoeba sp. has been detected in many countries, few cases have reportedly been recognized in South‐east Asia ( Mohammed Kamel & Norazah 1995; Kosrirukvongs et al . 1999 ).…”

Section: Introductionmentioning

confidence: 99%

Heterogeneity in cyst morphology within isolates of Acanthamoeba from keratitis patients in Thailand

Jongwutiwes

Pariyakanok

Charoenkorn

et al. 2000

Tropical Med Int Health

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SummaryWe isolated Acanthamoebae from the first two keratitis patients identified in Thailand in 1988 and 1990. The patients developed decreased vision, severe photophobia, severe eye pain and foreign body sensation after minor corneal trauma. The lesions included generalized superficial punctate keratitis, stromal corneal ulcer with keratic precipitate and uveitis in one case, and corneal ulcer with abscess in the other. Both cases were diagnosed by isolation of characteristic trophozoites and cysts of Acanthamoeba from corneal tissue by nonnutrient agar culture method. Based on cyst morphology, A. castellanii and A. polyphaga were detected in one case, and A. castellanii and A. triangularis in the other. Restriction fragment length polymorphism analysis of mitochondrial DNA (mtDNA-RFLP) revealed that each patient harboured a single parasite population. One shared mtDNA-RFLP with an authentic strain of A. castellanii, and the other gave a new unique pattern. Thus species identification of Acanthamoeba based on cyst morphology per se can be arbitrary, and mtDNA-RFLP may be more appropriate for accurate species/strain differentiation amongst morphologically heterogeneous populations of Acanthamoebae.

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First case of Acanthamoeba keratitis in Malaysia

Cited by 23 publications

References 2 publications

Perioperative treatment and prognostic factors for penetrating keratoplasty in Acanthamoeba keratitis unresponsive to medical treatment

Perioperative treatment and prognostic factors for penetrating keratoplasty in Acanthamoeba keratitis unresponsive to medical treatment

Kerentanan Acanthamoeba spp. terhadap Larutan Disinfektan Pelbagai Guna Kanta Sentuh

Heterogeneity in cyst morphology within isolates of Acanthamoeba from keratitis patients in Thailand

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