The due consideration of the proton OMP anomalies at sub-Coulomb energies for medium weight nuclei, particularly for nuclei off the stability line, is proved critical for analysis of 59 Cu(p, α) 56 Ni reaction. The cross-section uncertainty bands related to routine HF calculations, and particular proton OMP parameters off the stability line, respectively, are quite distinct and well separated. Validation of an α-particle OMP for proton-induced α-emission off the stability line, provided the above assumption is fulfilled, did a completion of similar data account for Cu stable isotopes at once with all α-induced reactions on Ni stable isotopes.