First Korean Case of <i>Cedecea lapagei</i> Pneumonia in a Patient With Chronic Obstructive Pulmonary Disease

Hong, Sung Kuk; Lee, Jee-Soo; Kim, Eui-Chong

doi:10.3343/alm.2015.35.2.266

Cited by 12 publications

(13 citation statements)

References 8 publications

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“…The majority of case reports related to ours have narrated good outcomes and favorable responses to antibiotics [ 1 , 6 – 9 , 13 , 14 ]. Antibiograms were performed in such cases, revealing an invariable resistance pattern.…”

Section: Discussionmentioning

confidence: 97%

“…Resistance to imipenem was not seen in most studies, but was in fact seen in our antibiogram. Not leaving it out may have contributed to our patient’s outcome [ 1 , 6 – 9 , 13 ] (Table 2 ).…”

Section: Discussionmentioning

confidence: 99%

“…Wound cultures were performed with positive results and fortunately ended with clinical success due to sensitive antibiotics [ 5 ]. Cedecea lapagei infections other than soft tissue infections have been documented [ 1 , 3 , 6 – 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…Because the discovery of Cedecea lapagei is relatively recent, and rarely diagnosed, there are few reported cases [ 1 , 3 – 9 ]. As well as soft tissue infection, scarce known cases of pneumonia, urinary tract infections, peritonitis, osteomyelitis, bacteremia, and sepsis have been documented [ 1 , 3 , 6 – 9 ]. To the best of our knowledge, there do not appear to be any reported cases of a catastrophic hemorrhagic bullae soft tissue infection in which the primary underlying etiology was Cedecea lapagei bacteria that swiftly evolved into septic shock and abrupt death [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

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Death related to Cedecea lapagei in a soft tissue bullae infection: a case report

et al. 2018

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BackgroundCedecea lapagei bacterium was discovered in 1977 but was not known to be pathogenic to humans until 2006. In the medical literature there are very few clinical case reports of Cedecea lapagei; none have reported a catastrophic death secondary to a soft tissue hemorrhagic bullae infection. As well as soft tissue infection, rare cases of pneumonia, urinary tract infections, peritonitis, osteomyelitis, bacteremia, and sepsis have been documented with the majority having good outcomes. Here, we present the first case of a fatal outcome in a Cedecea lapagei soft tissue infection with multiple hemorrhagic bullae.Case presentationA 52-year-old Mexican man with antecedents of liver cirrhosis and treated hypertension was brought to our institution with clinical signs of sepsis and 16 to 18 hours of history of pain and edema in his right lower limb. During the course of the first day hospitalized in our institution, he developed several large serohematogenous bullae with ascending progression on his entire right lower limb. He subsequently developed multiple organ failure and septic shock with rapid deterioration, dying on the second day. Bullae fluid samples taken the first day undoubtedly isolated Cedecea lapagei within the second day using MicroScan WalkAway® 96 plus System as well Gram-negative bacteria in MacConkey and blood agar.ConclusionsThe isolation of Cedecea lapagei was an unexpected etiological finding that will enable physicians in the future to consider this bacterium as a probable cause of serohematogenous bullae infections. We do not exclude contamination although it has never been isolated in bullae fluid in the medical literature. Future encounters with this bacterium should not be taken lightly as it may have the potential to have fatal outcomes.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Death related to Cedecea lapagei in a soft tissue bullae infection: a case report

et al. 2018

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“…izole edilen hastaların çoğu bağışıklığı baskılanmış hastalardır [3] . Cedecea infeksiyonlarının anlaşılması için tür düzeyinde tanımlanması son derece önemlidir [14] .…”

Section: Discussionunclassified

An Uncommon Cause of Bacteremia: Cedacia lapagei

Hassu¹,

Çelik²

2018

FLORA

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Enterobacteriaceae ailesi üyesi olan Cedecea cinsi bakteriler nadiren infeksiyon etkeni olarak karşımıza çıkmaktadır. Diyabet ve kronik hepatit C'ye bağlı hepatoselüler karsinoma öyküsü olan 85 yaşında kadın hasta; ikter, halsizlik ve ishal yakınmalarıyla Tıbbi Onkoloji Servisine yatırıldı. Hastanın yaşı ve kitlenin portal vene yakınlığı nedeniyle cerrahi rezeksiyon yapılamayan hastanın total bilirubin düzeyi 9.6 mg/dL'ye çıktığı için yatışının ikinci gününde transarteryel kemo-embolizasyon (TACE) ve bu girişimden üç gün sonra da perkütan transhepatik kolanjiyografi (PTK) girişimleri uygulandı. Son işlemden dört gün sonra hastanın 39°C'ye varan ateşleri olmaya başladı. İdrar ve periferik kateter kültürlerinde üreme olmayan hastanın alınan iki set kan kültürünün her ikisinde de üreme saptandı. BD Phoenix (Becton Dickinson, ABD) otomatize tanımlama ve duyarlılık sistemiyle bakteri Cedecea lapagei olarak tanımlandı. Antibiyotik duyarlılık testi "European Commitee on Antimicrobial Susceptibility Testing (EUCAST)" kriterlerine göre çalışıldı. Yalnızca tigesikline orta derecede duyarlılığı saptanan suş, diğer tüm antibiyotiklere dirençli olarak bildirildi. Tigesiklin ve meropenem tedavisi alan hasta yatışının 25. günü kaybedildi. Daha önce ülkemizden pnömoni ve üriner infeksiyon etkeni olarak bildirilmesine rağmen bildirilen ilk bakteremi olgusu olması nedeniyle olgu sunuldu.

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Coinfection of Cedecea lapagei and Aspergillus sydowii detected in bronchoalveolar lavage fluid of a patient with pulmonary infection using metagenomic next−generation sequencing: A case report

Yang,

Zhao,

et al. 2024

Heliyon

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First Korean Case of Cedecea lapagei Pneumonia in a Patient With Chronic Obstructive Pulmonary Disease

Cited by 12 publications

References 8 publications

Death related to Cedecea lapagei in a soft tissue bullae infection: a case report

Death related to Cedecea lapagei in a soft tissue bullae infection: a case report

An Uncommon Cause of Bacteremia: Cedacia lapagei

Coinfection of Cedecea lapagei and Aspergillus sydowii detected in bronchoalveolar lavage fluid of a patient with pulmonary infection using metagenomic next−generation sequencing: A case report

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