First Nationwide Study of the Prevalence of the Metabolic Syndrome and Optimal Cutoff Points of Waist Circumference in the Middle East

Objective: Some recent studies have shown stablity or declining trends in obesity while others still report increasing trends. The present study aimed to investigate the trends of obesity and abdominal obesity in Tehranian adults during a median follow-up of 10 years. Design: Prospective cohort study. Setting: Community-based data collection from the Tehran Lipid and Glucose Study (TLGS). Subjects: Participants from four phases of the TLGS from 1999 to 2011 (n 10 368), aged ≥20 years. Results: The crude prevalence of obesity and abdominal obesity increased from 23·1 % and 47·9 % at baseline to 34·1 % and 71·1 % at the end of follow-up, respectively. Generalized estimating equation (GEE) models were used to analyse the correlated data and calculate the relative risks (RR). Risks of obesity and abdominal obesity increased over the whole study period for men (RR = 1·62; 95 % CI 1·49, 1·76 and RR = 1·46; 95 % CI 1·41, 1·52, respectively) and women (RR = 1·24; 95 % CI 1·19, 1·29 and RR = 1·22; 95 % CI 1·18, 1·27, respectively). These rising trends were observed in all subgroups regardless of age, marital status and educational level. Conclusions: Trends of obesity and abdominal obesity are increasing in Tehranian adults during a decade of follow-up in both genders and in all study subgroups. These results underscore the still growing obesity epidemic in the capital of Iran, calling for urgent action to educate people in lifestyle modifications and the need for effective preventive and educational strategies on obesity.

show abstract

“…Values are expressed as mean and standard deviation or as percentages. *Obesity, BMI ≥ 30·0 kg/m 2 ; abdominal obesity, WC ≥ 89 cm (27) .…”

Section: Resultsmentioning

confidence: 99%

“…*Obesity, BMI ≥ 30·0 kg/m 2 ; class I, 30·0 ≤ BMI < 34·9 kg/m 2 ; class II, 35·0 ≤ BMI < 39·9 kg/m 2 ; class III, BMI ≥ 40·0 kg/m 2 . †Abdominal obesity: WC ≥ 89 cm in men and ≥91 cm in women (27) .…”

Section: Discussionmentioning

confidence: 99%

Rising trends of obesity and abdominal obesity in 10 years of follow-up among Tehranian adults: Tehran Lipid and Glucose Study (TLGS)

Barzin

Keihani

Hosseinpanah

et al. 2015

Public Health Nutr.

View full text Add to dashboard Cite

show abstract

“…Hence, in studies carried out on adult populations of India and Iran, the prevalence rates of MS varied from 33?7 % to 41 % (21)(22)(23) .…”

Section: Prevalence Of Metabolic Syndrome In the Worldmentioning

confidence: 99%

The prevalence of metabolic syndrome in Latin America: a systematic review

Márquez‐Sandoval

Macedo-Ojeda

Hörner

et al. 2011

Public Health Nutr.

169

View full text Add to dashboard Cite

Objective: To assess the available data on the prevalence of metabolic syndrome (MS) in Latin-American countries. Design: Systematic review. Searches were carried out in PubMed, ISIWeb, SCielo and Redalyc, using 'metabolic syndrome x' and 'prevalence' as keywords for titles and/or abstracts. Articles selected were cross-sectional studies in Latin-American countries, whose main objective was to study MS and whose study population is described below. MS must be determined using Adult Treatment Panel III criteria. Twelve studies with these criteria were selected, one of which was multi-centric. Setting: Latin America. Subjects: Apparently healthy subjects aged 18-65 years (including young adult, mature adult and elderly populations) of both genders. Results: The general prevalence (weighted mean) of MS in Latin-American countries was 24?9 (range: 18?8-43?3) %. MS was slightly more frequent in women (25?3 %) than in men (23?2 %), and the age group with the highest prevalence of MS consisted of those over 50 years of age. The most frequent components of MS were low HDL cholesterol levels (62?9 %) and abdominal obesity (45?8 %). Similar outcomes were obtained from the multi-centre study on Latin-American populations analysed. Conclusions: The present review brings us closer to an understanding of the prevalence of MS in Latin-American countries. However, it is not possible to know the full scope of the problem, partly because data from some countries are not available, and because the methodological differences among the studies published up to the present limit a joint analysis of their results.

show abstract

“…25 Our results are in line with two other studies on Iranian population; the first was a cross-sectional study on men and women aged 35-54 years, which analyzed the cutoff points of anthropometric variables for defining at least two major CVD risk factors by ROC analyses, 13 and the second was a national survey that showed that the cutoff point of WC for predicting at least two other components of the metabolic syndrome was 89 cm for men and 91 cm for women. 39 Lemieux et al 40 also defined the threshold value of B95 cm for WC in both genders and the values of 0.94 in men and 0.88 in women for WHR as corresponding to an accumulation of visceral adipose tissue. Welborn and Dhaliwal 29 reported approximately the same cutoff points in predicting all cause and CVD mortality in an Australian male population and the Asia-Oceania study recently pooled Iranian data with Australians' when comparing probable cutoff points with Asian populations.…”

Section: Obesity Variables To Predict Cardiovascular Events F Hadaeghmentioning

confidence: 99%

Appropriate cutoff values of anthropometric variables to predict cardiovascular outcomes: 7.6 years follow-up in an Iranian population

et al. 2009

View full text Add to dashboard Cite

Objective: To determine cutoff points of anthropometric variables for predicting incident cardiovascular disease (CVD) in Iranian adults. Design: It is a population-based longitudinal study. Subjects: A total of 1614 men and 2006 women, aged X40 years, free of CVD at baseline were included in the study. Measurements: Body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR) and cardiovascular risks were assessed. Incident CVD was ascertained over a median of 7.6 years follow-up. The adjusted hazard ratios (HRs) for CVD were calculated for 1 s.d. change in all obesity variables using Cox proportional hazards regression analysis. Receiver operator characteristic (ROC) curve analysis was used as the method of defining the points of the maximum sum of sensitivity and specificity (MAXss) of each variable as a predictor of CVD. Results: We found 333 CVD events during follow-up. The risk-factor-adjusted HRs were significant for all anthropometric variables in males and WHR in females and were 1.19, 1.24, 1.21 and 1.24 for BMI, WC, WHR and WHtR in males and 1.27 for WHR in females, respectively (all Po0.05). ROC analysis showed the highest area under curve (AUC) for WHR, WHtR and WC, followed by BMI in males and both genders agedp60 years. In females, WHR and WHtR had the highest AUC, followed by WC and BMI. Among those 460 years old, all the anthropometric variables showed same CVD predicting power. The cutoff values (MAXss) for CVD prediction in males and females were BMIs 26.95 and 29.19 kg m À2 ,WCs 94.5 and 94.5 cm, WHRs 0.95 and 0.90, and WHtR 0.55 and 0.62, respectively. Conclusion: There was no difference between central obesity variables in predicting CVD in males, whereas in females WHR and WHtR were more appropriate. The cutoff values of anthropometric variables were higher in the Iranian than in other Asian populations.

show abstract

First Nationwide Study of the Prevalence of the Metabolic Syndrome and Optimal Cutoff Points of Waist Circumference in the Middle East

Cited by 316 publications

References 18 publications

Rising trends of obesity and abdominal obesity in 10 years of follow-up among Tehranian adults: Tehran Lipid and Glucose Study (TLGS)

Rising trends of obesity and abdominal obesity in 10 years of follow-up among Tehranian adults: Tehran Lipid and Glucose Study (TLGS)

The prevalence of metabolic syndrome in Latin America: a systematic review

Appropriate cutoff values of anthropometric variables to predict cardiovascular outcomes: 7.6 years follow-up in an Iranian population

Contact Info

Product

Resources

About