First pediatric case of osteomyelitis caused by Robinsoniella peoriensis

İnal, Neşe; Karagöz, Alper; Turhan, Egemen; Hazırolan, Gülşen­

doi:10.1556/030.2020.01122

Cited by 4 publications

(3 citation statements)

References 14 publications

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“…Up until recently, there had been no reported cases of R. peoriensis infection in children. A recent case report in Turkey from İnal et al (10) wherein a child with an open fracture developed a wound infection and osteomyelitis bears some similarities to the present case. However, the mechanism and degree of gross contamination of the injury were not described and so it is unknown as to what risk factors, if any, this patient had for acquisition of R. peoriensis and subsequent infection.…”

Section: Diagnosissupporting

confidence: 78%

Robinsoniella peoriensis: An emerging pathogen and rare cause of wound infection in children

Krueger

Azad

Ramotar

et al. 2022

Official Journal of the Association of Medical Microbiology and

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BACKGROUND: Robinsoniella peoriensis is an anaerobic gram-positive bacilli first isolated from swine manure in 2003 but has since been associated with human infections. METHODS: We describe a pediatric case of R. peoriensis infection following a below-knee amputation for a limb injury and its treatment. Methods of identifying R. peoriensis and reported in vitro antimicrobial minimum inhibitory concentrations from the literature are reviewed. RESULTS: R. peoriensis is readily identifiable via 16S rRNA gene sequencing and Matrix-Assisted Laser Desorption Ionization-Time of Flight. There variability in the antibiotic susceptibility profiles reported in the literature, but antibiotics with low in vitro minimum inhibitor concentrations against R. peoriensis include beta-lactam/beta-lactamase inhibitors, carbapenems, vancomycin, and metronidazole. CONCLUSION: This is the first reported case of R. peoriensis infection following a traumatic injury in Canada to our knowledge and highlights the importance of recognizing this organism and other anaerobes in settings where wounds are grossly contaminated with soil.

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Section: Diagnosissupporting

confidence: 78%

Robinsoniella peoriensis: An emerging pathogen and rare cause of wound infection in children

Krueger

Azad

Ramotar

et al. 2022

Official Journal of the Association of Medical Microbiology and

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“…The literature search of the PubMed and Scopus databases yielded 52 non-duplicate studies. After screening all potentially eligible studies and the snowball procedure, only 14 studies met the inclusion criteria and were considered for data extraction [ 11 , 12 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. Figure 1 shows the flow diagram of study inclusion.…”

Section: Resultsmentioning

confidence: 99%

“…The first one is trauma with fractures, which necessitates orthopedic surgery. Indeed, six such patients were identified in the present review [ 12 , 21 , 22 , 24 , 25 ]. In most of these cases, trauma led to open fractures that could allow the inoculation of environmental pathogens in the patients’ bones or joints.…”

Section: Discussionmentioning

confidence: 99%

Robinsoniella peoriensis Infections in Humans—A Narrative Review

Ioannou,

Baliou,

Kofteridis

2024

Antibiotics

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Robinsoniella peoriensis is a Gram-positive, strictly anaerobic, spore-forming, rod-shaped bacterium belonging to the phylum Firmicutes and the family Lachnospiraceae. Until now, R. peoriensis is the only species of its genus. It was first isolated in 2003 during a study into the flora of lagoons and manure pits. Given the rarity of this microorganism and the sparse information in the literature about its way of transmission, the way to diagnose its infections and identify it in the microbiology laboratory, and its public health relevance, the present study aimed to identify all the published cases of Robinsoniella, describe the epidemiological, clinical, and microbiological characteristics, and provide information about its antimicrobial resistance, treatment, and outcomes. A narrative review was performed based on a Pubmed/Medline and Scopus databases search. In total, 14 studies provided data on 17 patients with infections by Robinsoniella. The median age of patients was 63 years and 47% were male. The most common types of infection were bone and joint infections, bacteremia, infective endocarditis, and peritonitis. The only isolated species was R. peoriensis, and antimicrobial resistance to clindamycin was 50%, but was 0% to the combination of piperacillin with tazobactam, aminopenicillin with a beta-lactamase inhibitor, and metronidazole which were the most commonly used antimicrobials for the treatment of these infections. The overall mortality depends on the type of infection and is notable only for bacteremia, while all other infections had an optimal outcome. Future studies should better assess these infections’ clinical and epidemiological characteristics and the mechanisms of the antimicrobial resistance of this microorganism from a mechanistic and genetic perspective.

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Robinsoniella peoriensis: an emerging pathogen with few virulence factors

McLaughlin

2022

Int Microbiol

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First pediatric case of osteomyelitis caused by Robinsoniella peoriensis

Cited by 4 publications

References 14 publications

Robinsoniella peoriensis: An emerging pathogen and rare cause of wound infection in children

Robinsoniella peoriensis: An emerging pathogen and rare cause of wound infection in children

Robinsoniella peoriensis Infections in Humans—A Narrative Review

Robinsoniella peoriensis: an emerging pathogen with few virulence factors

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