First report of immunogenic vasculitis with Wunderlich's syndrome following influenza B infection in a previously immunocompetent woman

Wunderlich’s syndrome in a young man of testicular mixed germ cell tumor with choriocarcinoma syndrome

“…Choriocarcinoma is most often seen as a component of mixed germ cell tumors in around 8-10% of cases. Choriocarcinomas most often metastasize early to other sites at the lung, liver and brain, and tend to hemorrhagic shock due to bleeding from metastatic sites of choriocarcinoma named choriocarcinoma syndrome [1][2][3][4]. A bleeding primary or metastatic choriocarcinoma of the kidney is rarely reported in the literature, which may present with fe-ver, gross hematuria and acute flank pain secondary to multiple micro aneurysms, hematoma and/or perinephric hemorrhage [6][7][8][9].…”

“…Wunderlich's syndrome is a rare but potentially life-threatening entity of spontaneous renal hemorrhage into the formation of perirenal and/or sub capsular hematoma, mostly due to vasculitis and renal tumors, such as renal angiomyolipoma, which is a benign mesenchymal tumor and is the most frequent cause [1][2][3][4]. The greatest risks of angiomyolipoma for bleeding are tumor size and grade of the vascular component of the tumor, especially where a diameter more than 4 cm [5].…”