First report of Trypanosoma cruziinfection in naturally infected dogs from southern Bahia, Brazil

Júnior, Nilo Fernandes Leça; Almeida, Valter dos Anjos; Carvalho, Fábio Santos; Albuquerque, George Rêgo; Silva, Fabiana Lessa

doi:10.1590/s1984-29612013005000003

Cited by 11 publications

(5 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Serological tests have been used due to the high costs of the PCR technique, which is used only for experimental purposes or to confirm discrepant serological results (OPAS, 2009). However, PCR results showed a low prevalence (0.5%) of natural T. cruzi infection in dogs, corroborating the results obtained by Leça-Júnior et al (2013), who also investigated the natural infection in domiciled dogs with the same technique and found a 0.7% infection rate.…”

Section: The Municipality Of Ituberá Is Endemic Forsupporting

confidence: 86%

“…Previous studies have already shown that dogs are naturally infected by this protozoan (GÜRTLER et al, 2007;LEÇA-JÚNIOR et al, 2013). The main clinical signs observed in these animals are anorexia, fever, lymphadenopathy, and cardiac alterations such as myocarditis, tachycardia, severe cardiac arrhythmia (CAMACHO, 2003;NELSON;COUTO, 2006), congestive heart failure, and diastolic dysfunction (PASCON et al, 2010;SANTANA et al, 2012).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Natural infection by Trypanosoma cruzi in dogs located in Ituberá, Southern Bahia, Brazil

Souza

Guedes

Oliveira

et al. 2018

SCA

Self Cite

View full text Add to dashboard Cite

ResumoA Doença de Chagas, causada pelo protozoário flagelado Trypanosoma cruzi, é uma antropozoonose de grande importância para a saúde pública. Diversas espécies de mamíferos são reservatórios do parasita, incluindo o cão. O objetivo deste trabalho foi verificar a infecção natural por T. cruzi na população de cães do município de Ituberá, Bahia. Foram avaliados 392 cães domiciliados, em todos os bairros do município, dos quais foram coletados 5mL de sangue para realização do diagnóstico molecular. A amplificação do DNA de T. cruzi foi através da Reação em Cadeia da Polimerase (PCR), com os primers P35 e P36, que amplificam um fragmento de 330 pb. Os produtos das PCRs foram submetidos à eletroforese em gel de agarose a 2% contendo Sybr (Invitrogen®). Dos 392 cães avaliados, apenas 2 (0,51%) animais, um macho e uma fêmea, foram positivos no diagnóstico molecular de T. cruzi. Conclui-se com esse estudo que há cães naturalmente infectados pelo T. cruzi no município de Ituberá-Bahia e que este achado constitui um alerta aos veterinários, profissionais da saúde e autoridades sanitárias locais, cujos cães podem atuar como reservatórios da doença. Palavras-chave: Canis familiaris. Diagnóstico molecular. Doença de Chagas. Tripanossomíase. AbstractChagas disease, caused by the flagellate protozoan Trypanosoma cruzi, is an anthropozoonosis of great importance for public health. Several species of mammals are reservoirs for this parasite, including dogs. The objective of this work was to verify the natural infection by T. cruzi in the population of dogs of the municipality of Ituberá, Bahia. A total of 392 domiciled dogs from all districts of the city were evaluated; five milliliters of blood was collected from the dogs for molecular diagnosis. T. cruzi DNA was amplified through the polymerase chain reaction (PCR); the primers P35 and P36, which amplify a fragment of 330 bp, were used. The PCR products were subjected to 2% agarose gel electrophoresis containing Sybr (Invitrogen). Of the 392 dogs evaluated, only 2 (0.51%) animals, one male and one female, tested positive for T. cruzi. This study concluded that there are dogs naturally infected by T. cruzi in the municipality of Ituberá-Bahia and that this finding is an alert to veterinarians, health professionals, and local health authorities that their own dogs can act as reservoirs of the disease.

show abstract

Section: The Municipality Of Ituberá Is Endemic Forsupporting

confidence: 86%

mentioning

confidence: 99%

Natural infection by Trypanosoma cruzi in dogs located in Ituberá, Southern Bahia, Brazil

Souza

Guedes

Oliveira

et al. 2018

SCA

Self Cite

View full text Add to dashboard Cite

show abstract

“…Dogs have been found infected by vector-borne protozoa, including Babesia gibsoni , Babesia vogeli , Rangelia vitalii , Hepatozoon canis , Leishmania amazonensis , Leishmania braziliensis , Leishmania infantum , Trypanosoma cruzi , and Trypanosoma evansi [ 73 , 78 - 82 , 85 , 87 - 90 , 96 , 102 - 104 , 109 - 113 , 117 - 121 ],[ 124 , 128 - 130 ]. Other protozoa of unknown pathogenicity (e.g., Trypanosoma caninum ) have also been described in Brazilian dogs [ 108 ].…”

Section: Reviewmentioning

confidence: 99%

Dogs, cats, parasites, and humans in Brazil: opening the black box

2014

View full text Add to dashboard Cite

Dogs and cats in Brazil serve as primary hosts for a considerable number of parasites, which may affect their health and wellbeing. These may include endoparasites (e.g., protozoa, cestodes, trematodes, and nematodes) and ectoparasites (i.e., fleas, lice, mites, and ticks). While some dog and cat parasites are highly host-specific (e.g., Aelurostrongylus abstrusus and Felicola subrostratus for cats, and Angiostrongylus vasorum and Trichodectes canis for dogs), others may easily switch to other hosts, including humans. In fact, several dog and cat parasites (e.g., Toxoplasma gondii, Dipylidium caninum, Ancylostoma caninum, Strongyloides stercoralis, and Toxocara canis) are important not only from a veterinary perspective but also from a medical standpoint. In addition, some of them (e.g., Lynxacarus radovskyi on cats and Rangelia vitalii in dogs) are little known to most veterinary practitioners working in Brazil. This article is a compendium on dog and cat parasites in Brazil and a call for a One Health approach towards a better management of some of these parasites, which may potentially affect humans. Practical aspects related to the diagnosis, treatment, and control of parasitic diseases of dogs and cats in Brazil are discussed.

show abstract

“…Dogs testing positive for T. cruzi (Leça-Júnior et al, 2012) were found in a rural area in this region.…”

Section: Discussionmentioning

confidence: 84%

Leishmania (Viannia) braziliensis in dogs in Brazil: epidemiology, co-infection, and clinical aspects

et al. 2015

View full text Add to dashboard Cite

ABSTRACT. Leishmaniasis is an endemic disease present in 98 countries. In Brazil, the northeast region accounts for approximately half of the cases in humans, and has experienced an increased number of positive cases in dogs. In this study, we investigated the epidemiology of canine leishmaniasis in the city of Ilhéus, Bahia, using serological and molecular techniques and evaluated the possible environmental risk factors and associated clinical signs. Blood samples were collected from 560 dogs in urban and peri-urban areas in Ilhéus, northeastern Brazil. Genomic DNA was extracted from the selected animals and 12063 Leishmania (Viannia) braziliensis in dogs ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 14 (4): 12062-12073 (2015) subjected to molecular analysis using Leishmania species-specific primers and diagnosis of Trypanosoma cruzi. A total of 54.72% of dogs were positive for Leishmania braziliensis, and animals positive for both Leishmania infantum and T. cruzi were not identified. Hematologic variables were not statistically associated with cases of L. braziliensis. However, the positive animal group showed lower red blood cell and platelet counts and higher levels of urea and serum creatinine. Few dogs presented clinical signs compatible with the presence of Leishmania. Age of more than 2 years and specific hair colors were associated with positive results for L. braziliensis. The geoclimatic characteristics of the region may improve parasite survival, reproduction, and vectors. This may explain the higher rate of dogs identified as positive in this study.

show abstract

First report of Trypanosoma cruziinfection in naturally infected dogs from southern Bahia, Brazil

Cited by 11 publications

References 27 publications

Natural infection by Trypanosoma cruzi in dogs located in Ituberá, Southern Bahia, Brazil

Natural infection by Trypanosoma cruzi in dogs located in Ituberá, Southern Bahia, Brazil

Dogs, cats, parasites, and humans in Brazil: opening the black box

Leishmania (Viannia) braziliensis in dogs in Brazil: epidemiology, co-infection, and clinical aspects

Contact Info

Product

Resources

About