2021
DOI: 10.1111/1471-0528.16979
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First‐trimester maternal haemodynamic adaptation to pregnancy and placental, embryonic and fetal development: the prospective observational Rotterdam Periconception cohort

Abstract: Objective To investigate whether first‐trimester maternal haemodynamic adaptation impacts placental, embryonic and fetal development as well as birth outcomes in pregnancies with and without placenta‐related complications. Design Prospective observational cohort. Setting A Dutch tertiary hospital. Population Two hundred and fourteen ongoing pregnancies. Methods At 7, 9 and 11 weeks of gestation, we assessed maternal haemodynamic adaptation (mean arterial blood pressure [MAP], uterine artery [UtA] blood flow) a… Show more

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Cited by 7 publications
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