Given the fact that Ukraine declares a European path of development and considers itself a potential member of the European Union, the study mainly examines the relationship between trust and economic growth in Ukraine and other countries of the world, including post-Soviet countries. The hypothesis that general trust has a positive effect on economic growth in general is tested, and a comparative assessment of the level and factors of trust across the regions of Ukraine has been carried out. The results show an historical tradition of mistrust of the state and its institutions particular to Ukraine as the country where the state has been perceived as foreign by most of the population for over 70 years; exceptional weakness and corruption of state administration, even by the standard of third-world countries; availability of influential and consistent stereotypes, partially universal and partly specific to post-communist countries. It causes polarization in society and within certain social groups and governmental institutions. Ukrainian society is characterized by the waste of symbolic capital of confidence in authorities. Meanwhile, there is some symmetry between mistrust of the system and trust in entities created by people to meet their spiritual, social, psychological, and other needs.