Fish oils, eicosanoid biosynthesis and cardiovascular disease: An overview

Turley, E.; Strain, J. J.

doi:10.3109/09637489309017433

Cited by 11 publications

(10 citation statements)

References 66 publications

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“…This was also observed in our study. Surprisingly, we did not observe any significant decrease in plasma TGs in the rats fed n-3 PUFAs, contrary to data reported in human clinical studies (4,44,47). In humans, this effect is usually attributed to EPA (13,49), and, in this study, plasma TGs were lower in the EPA group, although this difference was not significant.…”

Section: Discussioncontrasting

confidence: 99%

Dietary n-3 PUFAs affect the blood pressure rise and cardiac impairments in a hyperinsulinemia rat model in vivo

Rousseau¹,

Héliès-Toussaint²,

Moreau³

et al. 2003

American Journal of Physiology-Heart and Circulatory Physiology

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The cardiovascular consequences of eicosapentaenoic acid (EPA)- and docosahexaenoic acid (DHA)-specific intake were evaluated in vivo in a hyperinsulinemia (HI) model induced by dietary fructose intake. Wistar rats were fed a diet containing (or not for control) either EPA or DHA. The rise in blood pressure (BP), heart rate, and ECG were continuously monitored using an intra-abdominal telemetry system. The myocardial phospholipid fatty acid profile was significantly affected by DHA intake but less by EPA intake. The data indicated a reduced rise in BP in both DHA and EPA HI groups compared with controls. This result was confirmed by tail-cuff measurement after 5 wk [133.3 +/- 1.67 and 142.5 +/- 1.12 mmHg in n-3 polyunsaturated fatty acid (PUFA) and control groups, respectively], whereas n-3 PUFA did not affect BP in non-HI rats (116.3 +/- 3.33 mmHg). The heart rate was lower in the HI DHA group than in the other two dietary HI groups. Moreover, DHA induced a significantly shorter QT interval. It is concluded that the cardioactive component of fish oils is DHA through a mechanism that may involve the cardiac adrenergic system.

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Section: Discussioncontrasting

confidence: 99%

Dietary n-3 PUFAs affect the blood pressure rise and cardiac impairments in a hyperinsulinemia rat model in vivo

Rousseau¹,

Héliès-Toussaint²,

Moreau³

et al. 2003

American Journal of Physiology-Heart and Circulatory Physiology

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“…Fish oil is a good source of n-3 fatty acids and is known to be an immune-enhancing component. It has been reported that fish oil helps maintain the intestinal permeability (Turley and Strain, 1993;Wild et al, 1997;Bancroft et al, 2003;Kreymann et al, 2006), which normally undergoes disruption following burn injury. Hence, the lipids of DEF-BP were enriched with fish oil.…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, the composition of lipid, namely the proportion of polyunsaturated fatty acids (PUFA) with special reference to the ratio between n-6 and n-3 fatty acids (Narshimha Rao, 1993;Turley and Strain, 1993;Grester, 1995;Roy et al, 2004;Farreras et al, 2005), structured glycerides (Sandstorm et al, 1995;Roy et al, 2004), and medium-chain triglycerides (Ledeboer et al, 1995) is required to be incorporated in appropriate proportion. The beneficial effects of dietary fiber in normal nutrition are being extended to enteral nutrition (Cummings et al, 1980;Rushdi et al, 2004).…”

Section: Formulation Of Enteral Foods Introductionmentioning

confidence: 99%

Medical Foods from Natural Sources

Kaur¹

2009

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“…The content of SFAs in a human diet determines the cholesterol level in the blood serum. One of the indicators of the health quality of a food product is the intake of polyunsaturated fatty acids (PUFAs) and the n-6/n-3 fatty acids ratio, which, according to dieticians (Turley & Strain, 1993), should be in the range of 4 -6 : 1. According to the latest nutritional recommendations, saturated fatty acids should cover not more than 10% of daily energy demand.…”

Section: Discussionmentioning

confidence: 99%

Effects of adiCox®AP and monensin on production parameters and quality of meat of slow-growing Hubbard JA 957 broiler chickens

Łukasiewicz¹,

Michalczuk²,

Pietrzak³

et al. 2014

SA J. An. Sci.

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This experiment was conducted with 480 Hubbard JA 957 one-day-old broiler chicks to determine the effects of adiCox®AP, a plant coccidiostat, and monensin on production parameters and meat quality. The birds were randomly allocated to three experimental diets: (A) with the plant coccidiostat adiCox®AP; (M) with monensin, an ionophore coccidiostat; and (C) the control group without coccidiostats. The birds were reared on litter until 63 days of age. The bodyweight of chicks was recorded at the ages of 1, 12, 24, 42 and 63 days. The feed conversion ratio (FCR) and mortality ratio were calculated. There were no significant differences in bodyweight and FCR of birds tested across the experimental groups. In particular feeding groups, the mortality rate ranged from 2.60% to 4.33%, with the lowest number of deaths being noted in the groups receiving the plant coccidiostat (2.6%), whereas the highest mortality rate was recorded in the control group. The type of coccidiostat had no significant effect on the chemical composition of breast muscles. However, the leg muscles of the control chickens were characterized by a significantly higher content of protein (19.4%), compared with the groups receiving coccidiostats in the feed mixtures (19.1% in A and 18.6% in M). The plant coccidiostat effected a higher water-holding capacity (52.2%) and a lower cooking loss (6.9%) in the leg muscles of the birds. The administration of the plant feed supplement adiCox®AP significantly decreased the mortality rate of broiler chickens without compromising other production traits. The results also show that the applied plant preparation is an excellent alternative to antibiotic growth stimulants.

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Fish oils, eicosanoid biosynthesis and cardiovascular disease: An overview

Cited by 11 publications

References 66 publications

Dietary n-3 PUFAs affect the blood pressure rise and cardiac impairments in a hyperinsulinemia rat model in vivo

Dietary n-3 PUFAs affect the blood pressure rise and cardiac impairments in a hyperinsulinemia rat model in vivo

Medical Foods from Natural Sources

Effects of adiCox®AP and monensin on production parameters and quality of meat of slow-growing Hubbard JA 957 broiler chickens

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