Fissure sealants: a 4-year clinical trial comparing an experimental glass polyalkenoate cement with a bis glycidyl methacrylate resin used as fissure sealants

Williams, Brian; Laxton, L; Holt, R D; Winter, George

doi:10.1038/sj.bdj.4808989

Cited by 64 publications

(63 citation statements)

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“…Eight trials (31)(32)(33)(34)(35)(36)(37)(38) and three literature review articles (2,11,12), were accepted and thus formed the basis for the evaluation of evidence regarding the caries-preventive effect of GIC versus that of resin-based fissure sealants.…”

Section: Resultsmentioning

confidence: 99%

“…Two trials (31,36) reported a fluoride concentration ranging from 0.1 to 0.7 ppm in the water supply. Five trials (32)(33)(34)(35)38) provided no information about the water fluoride concentration.…”

Section: Description Of Accepted Trialsmentioning

confidence: 99%

“…Five trials (32)(33)(34)(35)38) provided no information about the water fluoride concentration. Only three trials (31,36,38) gave information about inter/intra-examiner reliability by means of kappa scores and none of the included trials examined the effect of potential confounders on their reported results. Only 2-year data was accepted of one trial, which also reported on 4-year results.…”

Section: Description Of Accepted Trialsmentioning

confidence: 99%

“…Of the 8 clinical trials (31)(32)(33)(34)(35)(36)(37)(38) included in this systematic review (Table 2), 7 followed a split-mouth study design (32-38) and 1 was a parallel-group study (31). In the splitmouth trials, the unit of randomization was the tooth.…”

Section: Description Of Accepted Trialsmentioning

confidence: 99%

“…Details about lossto-follow-ups were reported in all included studies. Treatment allocation was rated A (Adequate) (36,37) in two trials, B (Unclear) in five (32)(33)(34) and C (Inadequate) in the remaining two (35,38).…”

Section: Description Of Accepted Trialsmentioning

confidence: 99%

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Caries-preventive effect of glass ionomer and resin-based fissure sealants on permanent teeth: a meta analysis

et al. 2009

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Abstract:The purpose of this quantitative systematic review was to appraise the evidence on the caries-preventive effect of glass ionomer cement (GIC) in relation to resin-based fissure sealants. Nine English and two Portuguese databases were searched (15 January 2008). Randomized clinical trials and systematic reviews were considered for inclusion. Trial exclusion criteria were: drop-out rates > 33%; no randomization; baseline differences in groups not statistically adjusted; and no clinically important outcomes were presented. Two authors reviewed the articles independently. The outcome measure for the caries preventive effect was caries absence on sealed teeth. Of the 112 identified articles, 25 were selected for review. Of these, 14 were excluded and 11 accepted (8 trials; 3 systematic reviews). The accepted reviews provided no evidence of superiority of either sealant material. Six trials were included for meta-analysis. The pooled odds ratio was 0.96, 95% CI 0.62-1.49, indicating no difference in the caries-preventive effect of GIC and resin-based fissure sealant material. This systematic review with meta-analysis found no evidence that either material was superior to the other in the prevention of dental caries. Thus, both materials appear equally suitable for clinical application as a fissure sealant material. (J Oral Sci 51, 373-382, 2009)

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