In this study, new master theorems and general formulas of integrals are presented and implemented to solve some complicated applications in different fields of science. The proposed theorems are considered to be generators of new problems, including difficult integrals with their exact solutions. The results of these problems can be obtained directly without the need for difficult calculations. New criteria for treating improper integrals are presented and illustrated in four interesting examples and some tables to simplify the procedure of using the proposed theorems. The outcomes of this study are compared with those presented by Gradshteyn and Ryzhik in the classical table of integrations. The results in this study are simple and applicable in solving integrals, and some of the well-known theorems in calculating improper integrals are considered simple cases of our research.