Fitz-Hugh–Curtis syndrome

Theofanakis, Charalampos; Kyriakidis, A

doi:10.1007/s10397-010-0642-8

Cited by 24 publications

(14 citation statements)

References 23 publications

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“…Fitz-Hugh–Curtis syndrome is defined as peri-hepatic inflammation due to disseminated PID; with Chlamydia trachomatis and Neisseria gonorrhoea being the main aetiologic agents [7, 8]. The main mechanism of this pathology is attributed to hemato-lymphatic and peritoneal spread of pelvic infections to the liver and hyper-immune response to Chlamydia trachomatis infection [16]; with both processes leading to peri-hepatic and liver capsular inflammation.…”

Section: Resultsmentioning

confidence: 99%

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Chlamydia trachomatis-induced Fitz-Hugh–Curtis syndrome: a case report

et al. 2017

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BackgroundFitz-Hugh–Curtis syndrome is defined as perihepatitis associated with pelvic inflammatory disease. Chlamydia trachomatis is one of its most common aetiologies. This syndrome usually presents with right upper quadrant abdominal pain mimicking other hepatobiliary and gastrointestinal pathologies, hence, posing a diagnostic dilemma in settings with limited diagnostic tools.Case reportA 32 year old African female presented with acute right upper quadrant abdominal pain and vaginal discharge, for which she had previously received treatment in another health center with no improvement. Clinical and laboratory findings were suggestive of Fitz-Hugh–Curtis syndrome. Five days after treatment with oral doxycycline, the patient showed marked clinical improvement.ConclusionFitz-Hugh–Curtis syndrome is a common cause of right upper quadrant pain which is often under diagnosed in poor communities. Hence, it should be included as a differential diagnosis in patients presenting with right upper quadrant pain, especially in females of reproductive age.

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Section: Resultsmentioning

confidence: 99%

“…Chlamydia trachomatis and Neisseria gonorrhoea have been identified as the main aetiologies of PID and FHCS worldwide [7, 8]. FHCS is common among women of child bearing age, with a prevalence of 12–14% in women with PID [5].…”

Section: Introductionmentioning

confidence: 99%

Chlamydia trachomatis-induced Fitz-Hugh–Curtis syndrome: a case report

et al. 2017

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“…"Fitz-Hugh-Curtis" (FHC) syndrome, also known as acute perihepatitis, typically presents with "violin-string" adhesions between the liver and the anterior abdominal wall or the diaphragm [1], most commonly as a result of chlamydial or gonococcal infections [2]. Patients can be asymptomatic or present with clinical symptoms, such as pain and/or fever [3].…”

Section: Introductionmentioning

confidence: 99%

Fitz-Hugh-Curtis Syndrome: An Incidental Diagnostic Finding During Laparoscopic Sterilization

Grigoriadis¹,

Green²,

Amin³

et al. 2020

Cureus

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Fitz-Hugh-Curtis syndrome is associated with the presence of perihepatic adhesions, with or without associated symptoms. It is, most commonly, a result of chlamydial or gonococcal infections. We present a case of Fitz-Hugh-Curtis syndrome in an asymptomatic female patient who underwent a routine laparoscopic sterilization. The patient had, otherwise, normal intraoperative findings and negative laboratory investigations. The patient had a past history of tuberculosis infection, for which she had received treatment 10 years ago. We also present the literature relevant to our case report.

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“…Furthermore, frequency of FHCS diagnosis depends on the diagnostic criteria. 4 Theofanakis and Kyriakidis 4 remark about FHCS diagnoses where patients have no symptoms, only to find extended perihepatic adhesions during laparoscopy, while others with pelvic inflammatory disease and right upper quadrant pain might have no laparoscopic findings. Ultimately, they argue that the only secure way to diagnose FHCS is a laparoscopic exploration of the abdomen revealing the characteristic "violin-string" adhesions, which were first observed by Curtis in 1930.…”

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Lam

Jamidar

Aslanian

et al. 2020

The American Journal of Medicine

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We thank Yale et al for their comments. Yale et al responded that our case study with a 19-year-old woman diagnosed with Fitz-Hugh-Curtis Syndrome 1 (FHCS) may represent a pyogenic pelvic inflammatory disease with secondary diffuse peritonitis. They suggest that diffuse abdominal pain is not typical of a focal perihepatitis or FHCS, which presents with right upper quadrant abdominal pain. We propose that while right upper quadrant abdominal pain is the classic presentation of FHCS, it is not an absolute requirement for FHCS diagnosis. You et al 2 investigated the clinical features of FHCS in a retrospective study of 82 female patients diagnosed with FHCS after presenting to the Emergency Department in an urban teaching hospital with an annual load of 40,000 patients. Results revealed that upon physical examination, only 37/82 cases (45.1%) endorsed right upper quadrant abdominal pain, compared with 45/82 (54.9%) patients who had abdominal pain localized to a combination of right upper quadrant and other parts of the abdomen, whole abdomen, or other area except right upper quadrant. 2 Furthermore, one of the most complete early descriptions of FHCS was written by Malcolm Stanley in 1946. He described the pain of FHCS:

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Fitz-Hugh–Curtis syndrome

Cited by 24 publications

References 23 publications

Chlamydia trachomatis-induced Fitz-Hugh–Curtis syndrome: a case report

Chlamydia trachomatis-induced Fitz-Hugh–Curtis syndrome: a case report

Fitz-Hugh-Curtis Syndrome: An Incidental Diagnostic Finding During Laparoscopic Sterilization

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