Fixation of Atmospheric Carbonyl Compounds by Sodium Bisulfite

“…A third sample collected at room temperature failed to show the presence of methyl ethyl ketone. It is generally known that higher aldehydes and ketones react to only a limited extent to form bisulfite addition compounds (10), and Wilson (28) has shown that the rate of trapping methyl ethyl ketone as a bisulfite compound is considerably less at room temperature than in ice water.…”

Section: And Resultsmentioning

confidence: 99%

Paper Chromatographic Identification of Carbonyl Compounds as Their 2,4-Dinitrophenylhydrazones in Automobile Exhaust.

Barber¹,

Lodge²

1963

Anal. Chem.

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“…textile, dyes, adhesives), as well as in agriculture oper ations (e.g. seed disinfectants, insecticides), and is an in door and outdoor pollutant [7][8][9]. In vivo and in vitro stud ies have demonstrated formaldehyde-induced mutagene sis and carcinogenesis [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Mast Cell Response to Formaldehyde

Fujimaki

Kawagoe

Bissonnette

et al. 1992

Int Arch Allergy Immunol

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To examine the effects of the atmospheric pollutant formaldehyde on functionally distinct mast cells, peritoneal mast cells (PMC), intestinal mucosal mast cells (IMMC) and mouse bone-marrow-derived mast cells (BMMC) were incubated with various concentrations of formaldehyde. Pretreatment for 30 min with up to 100 μg/ml formaldehyde was not cytotoxic to mast cells. Formaldehyde (1–10 μg/ml) alone induced low levels of histamine release ( < 10%) from IMMC and BMMC. Antigen-induced histamine release was significantly increased in both PMC pretreated with low concentrations of formaldehyde (5-20 μg/ml) and BMMC pretreated with 10 μg/ml formaldehyde but decreased in PMC pretreated with a higher concentration (100 μg/ml) of formaldehyde. By contrast, antigen-induced histamine release was decreased in IMMC pretreated with formaldehyde in a dose-dependent manner. Histamine release stimulated with A23187 was also increased in PMC pretreated with a low concentration (10 μg/ml) of formaldehyde but decreased in those pretreated with a higher concentration (100 μg/ml) of formaldehyde. Pretreatment with 10 μg/ml formaldehyde significantly enhanced β-hexosaminidase release from PMC stimulated with antigen or A23187. Compared to sham-treated PMC, PMC pretreated with formaldehyde expressed a markedly depressed natural cytotoxicity for the tumor target WEHI-164 (an assay of tumor necrosis factor α activity). These results suggest that formaldehyde modifies various mast cell functions through alterations in cellular metabolism. Such effects may be important in respiratory and other diseases associated with formaldehyde exposure.

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Fixation of Atmospheric Carbonyl Compounds by Sodium Bisulfite

Cited by 29 publications

References 7 publications

Increasing Sensitivity of 3-Methyl-2-Benzothiazolone Hydrozone Test for Analysis of Aliphatic Aldehydes in Air.

Increasing Sensitivity of 3-Methyl-2-Benzothiazolone Hydrozone Test for Analysis of Aliphatic Aldehydes in Air.

Paper Chromatographic Identification of Carbonyl Compounds as Their 2,4-Dinitrophenylhydrazones in Automobile Exhaust.

Mast Cell Response to Formaldehyde

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