Roof-cutting and pressure-releasing technology are used to cut out the pressure transmission line of the critical blocks in the roof, causing the roof to totally collapse in the gob, while the NPR large deformation anchor cable support keeps the highway in its self-formed state. The gangue compactness has increased greatly when fully collapsed and filled to the gob's edge. At the end of the working face, the void ratio between rock blocks and the loose area is decreased, resulting in an observable shortening of the airflow disturbance distance at the working face and a change in the disaster gas accumulation law in the deep gob. It is critical to obtain the permeability characteristics of gob to avoid hazardous gas migration. The evolutionary model of the permeability of the mined-out region is created based on the analysis of the movement law of the overburden strata and the collapsed law of the gangue in the gob, and the "Z" ventilation model is built to research the airflow law in the gob. The following are the key conclusions reached: The 0-10 m airflow exchange zone is severe, the 10-45 m airflow return face is weak, the 45-190 m section airflow exchange is weak, and the 190-280 m section airflow confluence gob enhances the top corner's weak air area. The 0-50 m part of the self-formed Roadway has a wide air leakage channel, and good sealing methods have a significant impact on air leakage in the working face. The two-dimensional model constructed by comprehensive quantification of the main controlling factors, such as broken-expand, pressure, and filling degree, can represent the law of gas migration in the panel to a significant extent, and the reliability of the permeability evolution law is confirmed through data comparison and analysis.