Flapless closure of oro-antral communication with PRF membrane and composite of PRF and collagen – a technical note

Pandikanda, R.; Singh, Rakesh Kumar; Patil, Vinay; Sharma, Mandeep; Shankar, Kiruba

doi:10.1016/j.jormas.2018.12.012

Cited by 15 publications

(13 citation statements)

References 8 publications

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“…Contrary, there is little literature dealing with relevant information about the combination and biofunctionalization of CM and PRF-membranes. Some case reports stated PRF activated collagen matrices as a promising solution for sinus floor augmentation [57] or closure of oro-antral fistulas [58]. Ansarizadeh et al recently described the mechanistic properties of collagen-chitosan membrane activated with lyophilized PRF.…”

Section: Discussionmentioning

confidence: 99%

Biofunctionalization of porcine-derived collagen matrices with platelet rich fibrin: influence on angiogenesis in vitro and in vivo

et al. 2020

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Objectives Porcine-derived collagen matrices (CM) can be used for oral tissue regeneration, but sufficient revascularization is crucial. The aim of this study was to analyze the influence of platelet-rich fibrin (PRF) on angiogenesis of different CM in vitro and in vivo. Materials and methods Three different CM (mucoderm®, jason®, collprotect®) were combined with PRF in a plotting process. Growth factor release (VEGF, TGF-β) was measured in vitro via ELISA quantification after 1,4 and 7 days in comparison to PRF alone. In ovo yolk sac (YSM) and chorion allantois membrane (CAM) model, angiogenic potential were analyzed in vivo with light-and intravital fluorescence microscopy after 24 h, then verified with immunohistochemical staining for CD105 and αSMA. Results Highest growth factor release was seen after 24 h for all three activated membranes in comparison to the native CM (VEGF 24 h: each p < 0.05; TGF-β: each p < 0.001) and the PRF (no significant difference). All activated membranes revealed a significantly increased angiogenic potential in vivo after 24 h (vessels per mm 2 : each p < 0.05; branching points per mm 2 : each p < 0.01; vessel density: each p < 0.05) and with immunohistochemical staining for CD105 (each p < 0.01) and αSMA (each p < 0.05). Conclusions PRF improved the angiogenesis of CM in vitro and in vivo. Clinical relevance Bio-functionalization of CM with PRF could easily implemented in the clinical pathway and may lead to advanced soft tissue healing.

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Section: Discussionmentioning

confidence: 99%

Biofunctionalization of porcine-derived collagen matrices with platelet rich fibrin: influence on angiogenesis in vitro and in vivo

et al. 2020

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“…Likewise, Rachana et al used a 3-0 silk simple interrupted suture to do so. 1,25 According to the literature, this technique without manipulation of any additional flaps and auto-grafts has several advantages. Bilginaylar et al (2018) and Ramadan (2020) reported significantly lower pain and edema during the follow-up period in patients who were treated using PRF, compared to those treated by flap techniques.…”

Section: Patient Systemic Condition Preoperative Procedures Postopera...mentioning

confidence: 99%

“…The maxillary sinus takes place in the upper section of the body of maxilla, and as a normal variation, it includes the distal part of the alveolar process. As a result of this anatomical condition, there is a close relationship between maxillary teeth apices and the antrum 1,2 . Oroantral communication (OAC) is an opening between the maxillary sinus and the oral cavity, which can provide a pathway for oral microorganisms to cause an infection of the maxillary sinus 3 …”

Section: Introductionmentioning

confidence: 99%

“…Due to the mentioned disadvantages of surgical procedures, various alternative techniques for OAC closure have developed recently. These contain use of alloplastic materials (bio‐absorbable root analogues, hydroxyapatite), auto‐transplantation (bone transplant, third molar transplant), allo‐transplantation (fascia lata, dura mater, Human amniotic membrane), xenografts (bone materials, Collagen), prosthetic management and guided tissue regeneration techniques including autologous platelet or leukocytes (platelet‐rich fibrin and platelet‐ and leukocyte‐rich fibrin) 1,10,16,11,19,20 . Figure 1 shows the currently used techniques for OAC closure.…”

Section: Introductionmentioning

confidence: 99%

“…As a result of this anatomical condition, there is a close relationship between maxillary teeth apices and the antrum. 1,2 Oroantral communication (OAC) is an opening between the maxillary sinus and the oral cavity, which can provide a pathway for oral microorganisms to cause an infection of the maxillary sinus. 3 Various possible etiologic factors may cause this complication, due to the close relation between the root of maxillary posterior teeth, and its main cause is extraction of molars and premolars.…”

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confidence: 99%

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Non‐surgical management of oro‐antral communication using platelet‐rich fibrin: A review of the literature

et al. 2021

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Oro‐antral communication (OAC) is an opening between the maxillary sinus and the oral cavity, which can provide a pathway to cause an infection of the maxillary sinus. Although surgical techniques propose many advantages, several drawbacks have been reported in the previous studies. Bioactive modifiers such as platelet‐rich fibrin (PRF) are widely being used in oral surgery. Various studies have been conducted for closure of OACs using PRF. Due to the heterogeneity of the techniques found, we opted for a literature review to highlight the variety of techniques discussed in the literature. A comprehensive search of the PubMed, Google Scholar and Cochrane databases was performed for published articles between 2014 and 2021. Keywords for OAC management and repair and inclusion criteria were used to screen articles for final review. Out of 195 articles found, 12 articles were included to the study. Eight studies performed simple direct application of PRF clots, 2 studies used PRF in combination with collagen membrane and in 2 studies the treatment plan was to use buccal advancement flap reinforced by PRF. There were several variations among approaches to the closure of OAC using PRF in terms of treatment planning, pre‐ and post‐operative medication and preparation of PRF. Despite the mentioned variations, review of recent studies showed that all of the cases experienced full epithelialisation of OAC. This technique, without manipulation of any additional flaps and auto‐grafts, has several advantages. However, further research, both experimental and clinical, is necessary to unravel the success rate of using PRF in the management of OACs.

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OroAntral Communications and OroAntral Fistula

Manuel

2021

Oral and Maxillofacial Surgery for the Clinician

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Routine exodontia is a common procedure performed by the general dental practitioner and the oral surgeon alike. Most of the maxillary premolar/molar extractions heal uneventfully, but some may cause inadvertent opening into the maxillary sinus, manifesting as immediate oroantral communications (OACs) or delayed oroantral fistulae. The common reasons being difficulty encountered in the extractions intra-operatively due to myriads of reasons or the OAC may be due to a pre-existing pathology in the periapical region or within the sinus lining. Whatever the reason be, it is paramount that the surgeon identifies the problem and approaches it in a sequential manner to avoid long-term consequences and to attain a perfect closure. The timing of the closure is crucial, which is dependent upon the sinus health and the socket condition. This may be complicated by a missing root tip, which is lying in the sinus. This chapter aims to walk the reader through these events in a logical fashion so that they can take appropriate decisions and use the correct surgical technique, which will ensure successful closure of the defect.

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Flapless closure of oro-antral communication with PRF membrane and composite of PRF and collagen – a technical note

Cited by 15 publications

References 8 publications

Biofunctionalization of porcine-derived collagen matrices with platelet rich fibrin: influence on angiogenesis in vitro and in vivo

Biofunctionalization of porcine-derived collagen matrices with platelet rich fibrin: influence on angiogenesis in vitro and in vivo

Non‐surgical management of oro‐antral communication using platelet‐rich fibrin: A review of the literature

OroAntral Communications and OroAntral Fistula

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