Flavimonas oryzihabitans Bacteremia: Clinical Features and Microbiological Characteristics of Isolates

Abstract

Flavimonas oryzihabitans is rarely reported as a pathogen in humans. Twelve cases of F. oryzihabitans bacteremia were diagnosed at National Taiwan University Hospital over a 3-year period. The clinical features of these patients were analyzed, and antimicrobial susceptibilities and random amplified polymorphic DNA (RAPD) patterns of the 12 isolates were studied. Among these 12 patients, eight (67%) had underlying neoplastic diseases and all acquired F. oryzihabitans bacteremia while hospitalized. The clinical syndromes included primary bacteremia in 5 patients (42%), biliary tract infection in 3 (25%), and peritonitis, subdural empyema, infusion-related bacteremia, and pneumonia in 1 each. Polymicrobial bacteremia or concomitant fungemia was seen in three patients (25%). All the patients survived after antibiotic treatment. All isolates were susceptible to piperacillin, third-generation cephalosporins, aminoglycosides, and quinolones but resistant to cephalothin, cefuroxime, and trimethoprim. Susceptibility to aztreonam was variable (25%). The RAPD patterns differed among the isolates, indicating the epidemiological unrelatedness of these infections. F. oryzihabitans should be included as an etiology of severe nosocomial infection in patients with underlying debilitating diseases.

Temporal Variations in Cigarette Tobacco Bacterial Community Composition and Tobacco-Specific Nitrosamine Content Are Influenced by Brand and Storage Conditions

“…Both genera also contain species that are associated with disease in humans (Hatchette et al, 2000; Musher, 2001; Dutkiewicz et al, 2016). These include P. putida and P. oryzihabitans , which are generally considered opportunist pathogens (Yang et al, 1996), particularly P. oryzihabitans which has been linked to bacteremia, peritonitis, and pneumonia (Lin et al, 1997). …”

Antimicrobial susceptibility of uncommonly isolated non-enteric Gram-negative bacilli

“…This organism has also been reported to cause peritonitis in patients undergoing chronic ambulatory peritoneal dialysis [49]. Cellulites, abscesses, wound infections and meningitis following neurosurgical procedures have also been reported [50].…”

“…Only 30 clinical isolates of P. oryzihabitans were collected during the 7-year period of this study and the most active compound was imipenem (MIC 50 …”

A Rare Cause of Peritonitis Caused by Flavimonas Oryzihabitans in Continuous Ambulatory Peritoneal Dialysis (CAPD)

“…It was rarely implicated in septic conditions, such as bacteraemias [7][8][9], pneumonias [10], meningitides [11], soft tissue infections [12] and peritonitis [1][2][3][4], especially among immunocompromised hosts with implanted foreign materials, such as Hickman-catheters, Tenckhoff-catheters and joint prosthesis [13][14][15]. Both nosocomial and community-acquired type of infections have been reported, the latter showing an increasing tedency in recent years [10,12,[14][15][16]. In our case report the most likely route of infection was the exogenous-transluminal one, as both the exit site and the subcutaneous tunnel were lacking any signs of inflammation, and there was no evidence of any abdominal pathology to suggest leak of pathogens from the bladder or the intestine.…”