Flavonoids Extraction Kinetics, Antimicrobial Activity and Radical Scavenging Potential of Bulgarian Woundwort (Solidago virgaurea L.)

Yaneva, Zvezdelina; Simeonov, Evgeni; Rusenova, Nikolina; Ivanova, Donika; Nikolova, Galina; Karamalakova, Yanka; Chilev, Chavdar; Beev, Georgi

doi:10.3390/separations9020027

Cited by 6 publications

(3 citation statements)

References 43 publications

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“…In the antioxidant experiments, the antioxidant results of our group were similar to those of Chetan [ 30 ], Zvezdelina [ 31 ], and Dinh [ 32 ]. The results of the DPPH scavenging test for free radicals, superoxide anion free radical scavenging test, and high-concentration partial reducing ability test showed that LNT flavonoid powder has a higher free radical scavenging ability, which may be due to the low temperature protecting the structure of flavonoids from antioxidant activity.…”

Section: Discussionsupporting

confidence: 80%

Effects of Extraction Technique on the Content and Antioxidant Activity of Flavonoids from Gossypium Hirsutum linn. Flowers

Dong

Zhou

et al. 2022

Molecules

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Cotton is one of the Uyghur medical materials in China and is rich in flavonoids. Flavonoids have important pharmacological effects. The yield of flavonoids in traditional extraction methods is low, which affects the development of flavonoids. Therefore, it is urgent to optimize the extraction techniques. The yield of flavonoids in cotton flowers was effectively improved by response surface methodology, and the highest yield of flavonoids reached 5.66%, and the optimal extraction process conditions were obtained. The DPPH free radical scavenging rate, hydroxyl free radical scavenging rate, superoxide anion free radical scavenging rate, and reducing ability were tested to reflect the antioxidant capacity of flavonoids. The flavonoids had an excellent antioxidant effect. Cell experiments suggested that the flavonoids had the effect of protecting glutamate-induced damage to HT-22 cells. The results of this study provide a theoretical basis for the extraction of cotton flowers flavonoids and the comprehensive evaluation of antioxidant products, as well as the extraction of other plant flavonoids.

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Section: Discussionsupporting

confidence: 80%

Effects of Extraction Technique on the Content and Antioxidant Activity of Flavonoids from Gossypium Hirsutum linn. Flowers

Dong

Zhou

et al. 2022

Molecules

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“…High similarity was demonstrated in the chemical composition of both extracts, which suggests that the potential of both extracts is also similar in terms of biological effects. Many studies with medicinal plants in the modern literature indicate the use of ethanolic extracts, either because it allows use of important compounds such as flavonoids, or because it allows the development of future industrially convenient products [58,59].…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial activity: potential of Spondias purpurea (Anacardiaceae) against bacterial and fungal species

Oliveira

Greatti

Sorrechia

et al. 2022

Journal of Medical Microbiology

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Introduction. Plants have been used as medicines for centuries to treat human diseases. Studies with plants are extremely important for the development of future drugs that can benefit the human population. Hypothesis/Gap Statement. With the emergence of pathogens resistant to antimicrobial agents, there is an urgent need to direct research towards the discovery of new antimicrobials. Aim. In this study, Spondias purpurea L. (Anacardiaceae) was evaluated for its antimicrobial activity, antioxidant activity and cytotoxicity. Methodology. Antimicrobial activity was evaluated by the MIC using the 96-well plate microdilution technique of ethanolic, hexanic and dicloromethanic extracts of dried S. purpurea leaves against bacteria, yeast and filamentous fungi. The antioxidant activity of extracts was evaluated by the 2,2-diphenyl-1-picrylhydrazine (DPPH) method. To evaluate the safety of extracts, a cytotoxicity study against HaCat, J774 and HepG2 cells was performed. Results. The extracts had no activity against the bacteria at the maximum concentration of 5.0 mg ml−1, but showed fungistatic action against Candida species and dermatophytes. The ethanolic extract showed 88 % antioxidant activity and showed no significant cytotoxicity against the previously mentioned cells. Conclusion. This study showed that the 100 % ethanolic (EtOH) extract was favourable for antifungal and antioxidant activities and did not present significant cytotoxicity against the three studied cell lines, indicating that S. purpurea leaves are promising for the development of new antimicrobials.

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“…The goldenrod herb contains polyphenols, saponins and essential oils; this mainly applies to its leaves [32][33][34][35]. Thanks to these ingredients, goldenrod herb show diuretic, analgesic, anti-inflammatory, antifungal, as well as hypotensive and sedative effects [36][37][38][39]. Thus far, only the chemical composition and antioxidant properties of the whole goldenrod herb have been analyzed [33,40].…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and Antioxidant Activity of Asteraceae Family Plants

et al. 2022

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Plants of the Asteraceae family have been used in traditional medicine for thousands of years. Now, forgotten for some time, they are gaining popularity again. The aim of this study was to determine and compare the proximate composition and antioxidant activity of inflorescences and leaves of Taraxacum officinale F.H. Wigg. (common dandelion), Tanacetum vulgare L. (tansy) and Solidago virgaurea L. (European goldenrod). The content of dry matter, crude protein, crude ash and crude fat was determined according to the Association of Official Analytical Chemists (AOAC). The content of total polyphenols was determined using methanol extracts. Antioxidant activity was determined by three methods. The protein content was the highest in Taraxacum officinale. The fat and ash content increased in the sequence of Solidago virgaurea < Tanacetum vulgare < Taraxacum officinale. The total content of polyphenols in the material and its antioxidant activity (AA) were different between species. Changes were also observed in the morphological parts of the plants. The results of the research encourage the use of not only those parts of plants known but also inflorescences or leaves, which can be excellent ingredients for drugs and other preparations used in medicine or cosmetology and also in the food industry.

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Flavonoids Extraction Kinetics, Antimicrobial Activity and Radical Scavenging Potential of Bulgarian Woundwort (Solidago virgaurea L.)

Cited by 6 publications

References 43 publications

Effects of Extraction Technique on the Content and Antioxidant Activity of Flavonoids from Gossypium Hirsutum linn. Flowers

Effects of Extraction Technique on the Content and Antioxidant Activity of Flavonoids from Gossypium Hirsutum linn. Flowers

Antimicrobial activity: potential of Spondias purpurea (Anacardiaceae) against bacterial and fungal species

Chemical Composition and Antioxidant Activity of Asteraceae Family Plants

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