Flavonoids from Achyrocline satureioides with relaxant effects on the smooth muscle of Guinea pig corpus cavernosum

Comparative profiles of Achyrocline alata (Kunth) DC. and A. satureioides (Lam.) DC., Asteraceae, applying HPLC-DAD-MS

“…In others surveys, made in some cities of the state, in special those towards the Brazilian border with the Latin American country, in this case Paraguay and Bolivia, A. alata continued being cited as the most used species in popular medicine (Siqueira & Palhano, 1994). However, no pharmacological report of A. alata was found in the literature, whereas previously pharmacological evaluations were reported about A. satureioides, which showed antispasmodic and relaxing effects; anti-inflammatory (Simões et al, 1988, Hnatyszyn et al, 2004, Fachinetto et al, 2007, analgesic and sedative activities, effects on intestinal transit and antioxidant action (Desmarchelier et al, 1998, Leal et al, 2006, Grassi-Zampieron et al, 2009.…”

Plants popularly used for loosing weight purposes in Porto Alegre, South Brazil

“…DC. marcela reported by 1 herb sellers FL a , AP a , LE c , BR c Flavonoids (Ferraro et al, 1981;Gugliucci and Menini, 2002;Kadarian et al, 2002;de Souza et al, 2002); terpenoids, carotenoids, coumarins, esterols (Lorenzo et al, 2000;Gugliucci and Menini, 2002); sesquiterpenes and monoterpenes (Lorenzo et al, 2000;Gugliucci and Menini, 2002); dibenzofuran (achyrofuran) (Carney et al, 2002); phenylpyrone derived compounds (Simões et al, 1998); thiophene derived compounds (Macedo et al, 1997); caffeic, chlorogenic and isochlorogenic acids (Desmarchelier et al, 1998;Kadarian et al, 2002) Anti-hyperglicemic in mice (Carney et al, 2002); antioxidative in vitro (Desmarchelier et al, 1998); citotoxic against human hepatocellular carcinoma, in vitro (Ruffa et al, 2002); mutagenic and genotoxic, in vitro (Salmonella) (Vargas et al, 1990); hepatoprotective in mice (Kadarian et al, 2002); antispasmodic, anti-inflamatory and analgesic in mice (Langeloh and Schenkel, 1985;Simões et al, 1988); antibacterial (Simões et al, 1998); guinea pigs smooth muscle relaxation activity (Hnatyszyn et al, 2004) Amarum, aromatic, excitant, gastritis (D'ávila, 1910), digestive (D'ávila, 1910;Hoehne, 1939), antidiarrheic (Hoehne, 1939) Baccharis articulata (Lam.) Pers.…”

Immunomodulatory properties of Achyrocline satureioides (Lam.) D.C. infusion: A study on human leukocytes

“…D.C. (Compositae) is a medium-sized aromatic annual herb indigenous to South America, where it is known by the popular name of "Marcela". Its infusion is widely utilized for gastrointestinal inflammation and ants (Simoes et al, 1988;Hnatyszyn et al, 2004), antiglycation (Gugliucci and Menini, 2002) and blood glucose lowering agents (Carney et al, 2002), analgesic (Simoes et al, 1988), antiviral (Zanon et al, 1999;Bettega et al, 2004), antimicrobial (Anesini and Perez, 1993), insecticidal and trypanocydal (Rojas de Arias et al, 1995), cytotoxic against human hepatocellular carcinoma cells (Ruffa et al, 2002), sedative (Simoes et al, 1988), and even photoprotective after topical application (Morquio et al, 2005).…”