Flavonoids from<i>Litsea glaucescens</i>

López, José A.; Barillas, Wagner; Gómez-Laurito, Jorge; Lin, Fu-Tyan; Al‐Rehaily, Adnan J.; Sharaf, Maged H. M.; Schiff, Paul L.

doi:10.1055/s-2006-958054

Cited by 28 publications

(11 citation statements)

References 3 publications

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“…Chemically and pharmacologically, the American Litsea species are poorly known. A survey of flavonoids has been reported for L. glaucescens (López et al 1995), as well as an analysis of the essential oil of the leaves of L. glaucescens (Tucker et al 1992) and L. guatemalensis Mez (Vallverdú et al 2005). The aqueous and ethanolic extracts of Litsea guatemalensis leaves showed mild inhibition in vitro against Epidermophyton floccosum (Harz) Langeron et Miloch., Microsporum canis E. Bodin ex.…”

Section: Phytochemistry and Pharmacologymentioning

confidence: 99%

Essential Oils in Mexican Bays (Litsea spp., Lauraceae): Taxonomic Assortment and Ethnobotanical Implications1

et al. 2011

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Essential Oils in Mexican Bays (Litsea spp., Lauraceae): Taxonomic Assortment and Ethnobotanical Implications. The seven species of Litsea found in Mexico, all of them popularly known as "laurel," were surveyed by gas chromatography-mass spectrometry for their foliar essential oils composition and related ethnobotanical applications. Litsea glaucescens is in high demand as a condiment, and is sold in rural and urban markets all over Mexico. However, four other species are also locally used for food seasoning. Litsea guatemalensis is the species most used in traditional medicine, especially to treat fever, chills, infectious diseases of the digestive system, and arthritis. No reports of culinary, medicinal, or other applications were located for L. muelleri, and L. pringlei. This is the first report on the essential oils for L. neesiana, L. muelleri, L. parvifolia, L. pringlei, and L. schaffneri. The terpenoids commonly found in all the Litsea species studied were 1,8-cineole, linalool, α-pinene, β-pinene, mcymene, terpinen-4-ol, α-terpineol, caryophyllene, and caryophyllene oxide. Nevertheless, each species can be distinguished by its characteristic assortment of terpenoids. According to hierarchical cluster analysis, three groups of species were recognized: (1) 1,8-cineole group (C-10 terpenes), consisting of L. glaucescens, L. schaffnerii, L. pringlei, and L. muelleri; (2) limonene-rich group (C-10 oxygenated terpenes), including L. guatemalensis, and L. neesiana, and (3) oxygenated sesquiterpenes-rich group (C-15 oxygenated terpenes), comprising L. parvifolia. The chemical profiles of L. glaucescens and L. guatemalensis suggest a correlation with the culinary and medicinal uses of these species due to the known properties of their main constituents.Aceites esenciales de laureles mexicanos (Litsea spp., Lauraceae): Distribución taxonómica e implicaciones etnobotánicas. La composición de los aceites esenciales foliares de las siete especies de Litsea encontradas en México, todas ellas conocidas popularmente como "laurel," fue analizada por cromatografía de gases acoplada a espectrometría de masas y relacionada con sus usos tradicionales. Litsea glaucescens es altamente demandada como condimento y se vende en los mercados rurales y urbanos a lo largo de todo el país. Sin embargo, otras cuatro especies, también se utilizan localmente como especias. Litsea guatemalensis es la especie más usada en la medicina tradicional para tratar fiebre, resfriados, infecciones del aparato digestivo y artritis. No se registró ningún uso para L. muelleri y L. pringlei. Se reporta por primera vez la composición de los aceites esenciales de L. neesiana, L. muelleri, L. parvifolia, L. pringlei y L. schaffneri. Los terpenoides comunes en todas las especies estudiadas de Litsea fueron: 1,8-cineol, linalool, α-pineno, β-pineno, m-cimeno, terpinen-4-ol, α-terpineol, cariofileno y óxido de cariofileno, sin embargo, cada una de las siete especies puede distinguirse por un perfil característico de terpenoides. Con base en sus compuestos may...

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Section: Phytochemistry and Pharmacologymentioning

confidence: 99%

Essential Oils in Mexican Bays (Litsea spp., Lauraceae): Taxonomic Assortment and Ethnobotanical Implications1

et al. 2011

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“…Its leaves have been traditionally used as food seasoning, as well as remedy in folk medicine against central nervous system illness, depression, colic, pain, vomit, and diarrhea [ 21 ]. These activities are mainly related to the presence of different compounds such as terpenes and phenolic compounds [ 22 , 23 ]. The goal of the present study was to evaluate the seasonal effect on the antioxidant, antimicrobial, and the antiproliferative activities of L. glaucescens Kunth leaves extracts, as well as on their content and profile of phenolic compounds, since to the best of our knowledge, this is the first effort to describe at this level the biological properties and chemical composition of “laurel,” commonly used as a remedy by the communities from the mountainous region of Veracruz, México.…”

Section: Introductionmentioning

confidence: 99%

Seasonal Effect on the Biological Activities of Litsea glaucescens Kunth Extracts

López-Romero

González‐Ríos

Peña-Ramos

et al. 2018

Evidence-Based Complementary and Alternative Medicine

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This study shows the seasonal effect on the antioxidant, antiproliferative, and antimicrobial activities of L. glaucescens Kunth (LG) leaves extracts. Their antioxidant activity was evaluated through the DPPH, FRAP, and ORAC assays. Their phenolic content (PC) was determined by means of the Folin-Ciocalteu method, and the main phenolic compounds were identified through a HPLC-DAD analysis. Antiproliferative activity was determined by MTT assay against HeLa, LS 180, M12.C3.F6, and ARPE cell lines. Antimicrobial potential was evaluated against Staphylococcus aureus and Escherichia coli using a microdilution method. All the LG extracts presented high antioxidant activity and PC, with quercitrin and epicatechin being the most abundant. Antioxidant activity and PC were affected by the season; particularly autumn (ALGE) and summer (SULGE) extracts exhibited the highest values (p < 0.05). All extracts presented moderate antiproliferative activity against the cell lines evaluated, HeLa being the most susceptible of them. However, ALGE and SULGE were the most active too. About antimicrobial activity, SULGE (MIC90 < 800 μg/mL; MIC50 < 400 μg/mL), and SLGE (MIC50 < 1000 μg/mL) showed a moderate inhibitory effect against S. aureus. These findings provide new information about the seasonal effect on the PC and biological properties of LG extracts. Clearly, antioxidant activity was the most important with respect to the other two.

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“…The species L. rubescene and L. peduncalt have long been used in traditional Chinese medicine for the treatment of gastroenterologia, oedema and rheumatic arthritis [3]. Most Litsea plants contain alkaloids, flavonoids [4], terpenes [5], lactone [6] and volatile oils constitution [7]. Several biologically active compounds were isolated and their structures have been elucidated by many researchers [3, 8].…”

Section: Introductionmentioning

confidence: 99%

Insights from the docking analysis of biologically active compounds from plant Litsea Genus as potential COX-2 inhibitors

Gogoi¹,

Bezbaruah²,

Bordoloi³

et al. 2012

Bioinformation

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Litsea spp of Laural family are traditionally used as herbal medicine for treating inflammation including gastroenterologia, oedema and rheumatic arthritis. Therefore, it is of interest to investigate and understand the molecular principles for such actions. Here, we have illustrated the binding of thirteen Litsea derived biologically active compounds against the inflammation associated target COX (cyclo-oxygenase) -2 enzymes. We compared the binding information of these compounds with a selected number of already known COX-2 inhibitors. The comparison reflected that some of these compounds such as linderol, catechin, 6'-hydroxy-2',3',4' - trimethoxy-chalcone and litseaone have better or equivalent binding features compared to already known inhibitory compounds namely celecoxib, acetylsalicylic acid, rofecoxib. Therefore, all these small compounds reported from plant Litsea spp were found to possess potential medicinal values with anti-inflammatory properties.

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Flavonoids fromLitsea glaucescens

Abstract: MeOH (4:1) (BST inactive) and EtOAc (BST l3Opg/ml). Column chromatography of the EtOAc fraction over silica gel, and elution with CHC13, followed by CHC13-MeOH

Cited by 28 publications

References 3 publications

Essential Oils in Mexican Bays (Litsea spp., Lauraceae): Taxonomic Assortment and Ethnobotanical Implications1

Essential Oils in Mexican Bays (Litsea spp., Lauraceae): Taxonomic Assortment and Ethnobotanical Implications1

Seasonal Effect on the Biological Activities of Litsea glaucescens Kunth Extracts

Insights from the docking analysis of biologically active compounds from plant Litsea Genus as potential COX-2 inhibitors

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