Flaxseed Cysteine Protease Exhibits Strong Anticoagulant, Antiplatelet, and Clot-Dissolving Properties

Nandish, Sharath Kumar M.; Kengaiah, Jayanna; Ramachandraiah, Ch; Chandramma,; Shivaiah, Ashwini; Santhosh, Sebestian; Thirunavukkarasu,; Sannaningaiah, Devaraja

doi:10.1134/s0006297920090102

Cited by 10 publications

(5 citation statements)

References 43 publications

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“…As reported by several authors, the protein content in quiescent seeds represents a fundamental nitrogen source which is essential for plant growth and development [ 15 , 16 , 21 ]. Although the Bradford assay cannot be used to identify enzymatic proteins in aqueous extracts, the presence of proteolytic enzymes in oil seeds has already been proven by various authors [ 14 , 22 , 23 ].…”

Section: Resultsmentioning

confidence: 99%

“…As reported by several authors, the protein content in quiescent seeds represents a fundamental nitrogen source which is essential for plant growth and development [15,16,21].…”

Section: Protein Content In Aqueous Oilseed Extractsmentioning

confidence: 91%

“…[13]. Aspartic endopeptidases with strong proteolytic activity were extracted from sesame seeds [14] and a cysteine protease was isolated from the flaxseed extract for pharmaceutical applications [15]. As reported by Tan-Wilson and Wilson [16], it is evident that oilseeds generally contain various types of proteolytic enzymes that play essential roles in germination and maturation.…”

Section: Introductionmentioning

confidence: 98%

“…The earliest written reference to the safflower seed was made by Lucius Junius Columella in his treatise De Re Rustica (c. 50 bc): ‘… though it can also be coagulated with the flower of the wild thistle or the seeds of the safflower….’ [ 13 ]. Aspartic endopeptidases with strong proteolytic activity were extracted from sesame seeds [ 14 ] and a cysteine protease was isolated from the flaxseed extract for pharmaceutical applications [ 15 ]. As reported by Tan-Wilson and Wilson [ 16 ], it is evident that oilseeds generally contain various types of proteolytic enzymes that play essential roles in germination and maturation.…”

Section: Introductionmentioning

confidence: 99%

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Oilseed Extracts from Local Markets as Promising Coagulant Agents for Milk from Various Mammalian Species

Liburdi

Cucci

Esti

2022

Foods

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The aim of this study was to identify novel milk coagulants to be used in cheesemaking. For this purpose, aqueous extracts from safflower (Carthamus tinctorius), sunflower (Helianthus annuus), flax (Linum usitatissimum) and sesame (Sesamum indicum) seeds were tested for their caseinolytic (CA) and milk coagulating properties (MCA) in skim milk at temperatures of 25, 37, 50, 65 and 80 °C. The seed oil samples with the highest temperature ranges in regard to coagulation efficiency were then tested in cow, buffalo, goat and sheep milks and the MCA and curd yield (CY) parameters were measured at different temperatures. Due to their high milk coagulation efficiency (CE) in all types of milk and at different temperatures, the sesame and sunflower seed extracts proved to be particularly interesting and their CY parameters were similar to those obtained with animal rennet. Moreover, our results confirm that oilseed coagulants are capable of coagulating milk and can also be considered as potential animal rennet substitutes. This study provides valuable insights into the development of potential vegetable coagulants that could be used for various production processes aimed at specific target consumers.

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Section: Resultsmentioning

confidence: 99%

“…As reported by several authors, the protein content in quiescent seeds represents a fundamental nitrogen source which is essential for plant growth and development [15,16,21].…”

Section: Protein Content In Aqueous Oilseed Extractsmentioning

confidence: 91%

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

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Oilseed Extracts from Local Markets as Promising Coagulant Agents for Milk from Various Mammalian Species

Liburdi

Cucci

Esti

2022

Foods

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“…Os resultados deste estudo sugeriram que a linhaça possui ação anti-inflamatória, antibacteriana e antiespasmódica através de múltiplas vias e, portanto, oferece potencial promissor a ser desenvolvido para controle da doença inflamatória intestinal MORSHEDZADEH et al, 2019). e menor agregação plaquetária(NANDISH et al, 2020); após o consumo de óleo de linhaça e de linhaça em grão. Como citado anteriormente, o EPA produzido a partir de ALA pode inibir a produção ou a conversão dos metabólitos do AA, que são pró-inflamatórios.…”

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Linhaça: Composição, Compostos Bioativos E Efeitos Fisiológicos Na Saúde Humana

Sales¹,

Pimenta²,

Costa³

2021

Linhaça: Perspectiva De Produção E Usos Na Alimentação Humana E Animal

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Direitos para esta edição cedidos à Atena Editora pelos autores. Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0).O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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Synthesis, structural characterization, CT-DNA interaction study and antithrombotic activity of new ortho-vanillin-based chiral (Se,N,O) donor ligands and their Pd complexes

Kumar

et al. 2021

Inorganica Chimica Acta

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Flaxseed Cysteine Protease Exhibits Strong Anticoagulant, Antiplatelet, and Clot-Dissolving Properties

Cited by 10 publications

References 43 publications

Oilseed Extracts from Local Markets as Promising Coagulant Agents for Milk from Various Mammalian Species

Oilseed Extracts from Local Markets as Promising Coagulant Agents for Milk from Various Mammalian Species

Linhaça: Composição, Compostos Bioativos E Efeitos Fisiológicos Na Saúde Humana

Synthesis, structural characterization, CT-DNA interaction study and antithrombotic activity of new ortho-vanillin-based chiral (Se,N,O) donor ligands and their Pd complexes

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